Index / What Works / Dr. Sam Ellis on mature skin

Dr. Sam Ellis on What Really Works for Mature Skin

She reviewed 37 mature-skin products, approving 30 and reaching a Guru Score of 81%, with four named as category favorites.

81%Guru Score
30 Approved4 Mixed3 Skip

Dr. Sam Ellis has covered 37 products for mature skin. Her record comes in at a Guru Score of 81%. She approves more than she skips, but her bar on evidence is firm. If a pricier product is going to get her backing, she expects clinical data.

What does Dr. Sam Ellis recommend for mature skin?

Vitamin C, retinoids, and peptides show up again and again in her approved takes. She named CeraVe Skin Renewing Vitamin C Serum a winner because it uses L-ascorbic acid. That's the most proven form of vitamin C. She says the slightly lower concentration suits sensitive skin especially well. For pricier products, she looks for clinical data before she backs them. She approved SkinMedica TNS Advanced+ Serum because it has studies behind it. Those studies show real improvements in fine lines, wrinkles, and even sagging around the neck. Very few products can say that.

In their words

"Let's start off with a drugstore option, the CeraVe Skin Renewing Vitamin C Serum. This is going to run you about $24 to $30 depending on which retailer you are purchasing it from. It is 10% L-ascorbic acid, so a slightly lower concentration than your average vitamin C product. And what I really like about it is the consistency. It's sort of like a thicker gel. And a lot of vitamin C serums are very watery, which makes them great for layering, but it can also make them kind of messy. Aside from that ascorbic acid, it also has those skin barrier supporting ceramides that CeraVe is super well known for. And I would have to say this is one of my absolute favorite budget friendly vitamin C serums. It's very fairly priced. It's good for travel. It still has the most proven form of vitamin C, ascorbic acid, at a slightly lower concentration. So if someone does have slightly sensitive skin, but still wants to be using the most proven form of vitamin C, excellent option."
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"One of my favorites for this is the Timeless Coenzyme Q10 Serum. This not only has the coenzyme Q10, but also has Matrixyl 3000, which is probably the best anti-aging peptide. So you get a peptide, you get coenzyme Q10 in this really luxurious, non-irritating serum that you can use morning or night. It's also super affordable."
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"Adapalene, also known as Differin Adapalene 0.1% gel, used to be a prescription retinoid you could only get from your doctor but it's now available over the counter and that is so wonderful. If you're looking for a retinoid that's available over the counter to help you with your acne, this is absolutely my number one choice. Do not bother with retinols or retinoic acid. Adapalene is known as a third generation retinoid so it's going to work on those retinoic acid receptors within your skin but it's considered to be a lot more gentle and people tend to have less irritation when using something like adapalene compared to tretinoin. There are studies showing that 0.1% adapalene is just as effective as 0.025% tretinoin. Within the US, this is the most potent retinoid that you can get over the counter without a prescription."
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"I do recommend light therapy masks if you can be consistent with them. They're not a total waste of money. [...] There are tons of LED mask brands out there. The two I typically recommend are by Omnilux and by Current Body. Those masks both have the right specs to get you the right results. They have the right power to get you the right results. And they're both really high quality masks. I have used both and loved both."
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"If you have really sensitive skin but you still really want to incorporate a retinoid into your skincare routine, I would try the Olay Regenerist Retinol. This is a little bit more gentle, it's in a more creamy base, and you still get those skin strengthening retinoid benefits."
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"This is a peptide and growth factor serum. You just need one pump for your entire face and neck. It's definitely a more expensive skincare product, and I always say if you're going to invest a hundred or more dollars in a skincare product, it should generally have some type of clinical trials showing its efficacy. This has good clinical data showing it helps with fine lines, wrinkles, and even skin sagging. There's not a lot in skincare that helps with sagging. It's not going to lift your jowls up, but for people who apply it to their neck or around their eyes, they do notice noticeable improvements. This is just a product I really enjoy using. As someone with rosacea and more reactive skin, I also find it quite calming and not irritating. I'm a big fan. They recommend using it morning and night, generally on clean skin."
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How many products has Dr. Sam Ellis reviewed for mature skin?

Dr. Sam Ellis has reviewed 37 products for mature skin, for a Guru Score of 81%. 30 approved, 4 mixed, and 3 skipped.

What has Dr. Sam Ellis skipped for mature skin?

All three products she skipped are at-home devices, and her concern each time comes down to evidence. She skipped NuFACE Trinity Microcurrent Device and ZIIP Halo 2.0 because microcurrent targets muscle tone. But she says aging faces lose lift because other tissues loosen, not because muscles weaken. So the results tend to be subtle at best. She skipped NIRA Precision Laser for a similar reason. Its wavelength resembles a clinic-grade laser, but the power is far too low to stimulate collagen in any meaningful way.

What should you take from Dr. Sam Ellis's picks?

Dr. Sam Ellis's mature-skin record rewards evidence and ingredient quality over price. She named four outright winners. They range from the affordable CeraVe Skin Renewing Vitamin C Serum to the premium SkinCeuticals C E Ferulic, making clear that budget does not decide her verdict. Anyone looking for a dermatologist's take in plain language will find her 37 reviews a solid place to start.

Watch Dr. Sam Ellis say it

Every verdict here comes from a video. These are the moments themselves, each one jumping straight to the bit about that product.

About this expert

See everything Dr. Sam Ellis has reviewed

Related guides

This guide reflects what Dr. Sam Ellis said across their videos about 37 products for mature skin, aggregated by The Guru Index. Sponsored takes are excluded. The Guru Score is our read on how warmly they talk about them. It is general information, not medical advice.