What is NIOD Copper Amino Isolate Serum 3?

A copper amino isolate serum designed to support skin health and anti-aging concerns.

Is NIOD Copper Amino Isolate Serum 3 worth it?

Mostly yes. 7 of the 8 gurus who reviewed it give it their stamp of approval, for a Guru Score of 90%.

What is NIOD Copper Amino Isolate Serum 3's Guru Score?

NIOD Copper Amino Isolate Serum 3 holds a Guru Score of 90%. That is our read on how warmly the experts talk about it, based on the verdicts of 8 independent expert reviewers we have collected. It is also Guru Certified, our mark for products that hold broad approval across many expert reviewers.

Who is NIOD Copper Amino Isolate Serum 3 best for?

NIOD Copper Amino Isolate Serum 3 is generally suited to mature skin.

NIOD Copper Amino Isolate Serum 3

Every take, in full

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

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No BS Beauty

89k subs · 3k devotees

✓Approved

"This is the Niod Copper Amino Isolate Serum, which is 93 bucks. The main difference between this and the Ordinary copper peptide serum is the texture. This one's got a very water-like texture, so it's pretty easy to fit into most routines, whereas the Ordinary has kind of a gel serumy texture. It's got 1% copper peptides, tripeptide 29, which they say helps with collagen production, vitamin E, and retinol peptide 189, which is claimed to function similar to retinol."

Top Pick: luxury copper peptide serum

All 3 takes from No BS Beauty

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"Last but not least is the NIOD Copper Amino Isolate Serum 3, which is 47 bucks. This is a copper peptide serum, great for nighttime use to help with anti-aging. We've got 1% copper peptides, we've got vitamin E, we've got that retinol peptide 189, and then we've got proline peptide. It's just a water-based peptide serum, and this one's really nice. In addition to those ingredients, we have an ingredient called tholin 4, which is a peptide that's claimed to work with the youth hormone called thotin. It works by compensating for the loss of thymic factors that come with age, and it's thought to stimulate the skin's immune defenses and help the skin regenerate and produce more collagen, which is what we all want. So buy this for the copper peptides and the other peptides in here, and keep using it for the other beneficial goodies in here. It's really a nice serum."

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"Next up would be my luxe pick or more pricey pick. So if you like a little bit more expensive ones, this is a good one. It's the NIOD Copper Amino Isolate Serum. This size retails for 93 bucks, so it is on the more expensive side. It's got 1% copper peptides, and in addition to that, it's got tripeptide-29, which the manufacturers say helps with collagen production, vitamin E, it's got the retinopeptide 189, which is a peptide that claims to have results similar to retinol, increasing skin cell turnover and promoting the synthesis of collagen, and then we've also got the thymulin-4 peptide thought to help stimulate the skin's immune defenses and help the skin regenerate. Really nice watery based serum, easy to fit in with any routine, but definitely on the more expensive price point."

Dr. Sam Ellis

861k subs · 127k devotees

✓Approved

"One of the most respected products in this space is the NIOD Copper Amino Isolate Serum 3. It's around $65 and is formulated with a 1% copper peptide complex that can help improve skin elasticity and structural anti-aging. It's a great product. A quick practical note, don't layer copper peptides with ascorbic acid, vitamin C. So if you use a vitamin C in the morning, go with your peptides at night."

Mad About Skin

722k subs · 10k devotees

✓Approved

"First and foremost, we have the NIOD Copper Amino Isolate Serum. This has been a staple in my routine for years. I think this was one of the first peptide serums I ever used and I've absolutely loved it. It's not the cheapest product out there, but it's definitely an advanced formula that makes sure those peptides get to where they need to be in the skin in order to deliver maximum benefit. Such a great product, such a great formula, and definitely for people that have used peptides for some time and want to kind of kick it up a notch, this is a product that will definitely help you to achieve that. NIOD actually have a 23% off sale which ends at the end of April, so I've just stocked up on this one cause I love it, and that really does bring that price point down. This is an advanced product that definitely takes your peptide game to the next level."

All 8 takes from Mad About Skin

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"If you want to go for the most advanced copper peptide option, then you could reach for the NIOD Copper Amino Isolate Serum 3. This is a fantastic, fantastic product that has multiple layers of technology to make sure those copper peptides are getting to where they need to be to give you quick and effective results. It's also got a great blend of peptides in here which are really going to double down on that collagen production. This is amazing. And because it's part of that ordinary family, they currently have a 23% off sale on this product, which will bring that price point down a little bit. Full price, it is actually a little bit out of the reach of a lot of people, but with that sale on, it will make it slightly more accessible. I think the main reason that people don't opt for copper peptides like the one by NIOD is they find them too complicated. There are lots of things you can't layer and pair alongside them because they can damage the copper peptides, meaning ultimately you're wasting your money."

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"If you want a product that does it all super quick time gives you like the maximum results then I would recommend going for the neod copper Amino isolate serum"

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"The standout performer of today is the Copper Amino Isolate Serum by NIOD, the copper peptide I'm using today. There are others on the market, but hands down it's the best copper peptide on skincare planet Earth. It's normally about eighty pounds here in the UK. The technology far outstrips anything else on the market. I do love this, but I will only buy it when it's on sale, I'm too cheap to buy it full price."

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"If you prefer something that isn't in a lipid base but is more traditional serum, then the Copper Amino Isolate Serum is a great option, very similar in terms of outcomes, but this is a little bit more lightweight and has a slightly lower price point. It'll depend what you're looking for, but if you're on a slightly lower budget, don't feel you have to compromise, this is a really great anti-aging option."

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"You only need to use a tiny amount and it spreads beautifully on the skin, so that makes the application super easy. The NIOD Copper Amino Isolate Serum 3 has the same great copper peptide blend as the lipid version, but it's in a more watery serum base. I think this is really going to come down to preference in terms of what you like in terms of texture. If you want something that sinks in super quick, then the serum might be more for you. I tend to mix and match between the two depending on what my skin needs. In summer I will go for the serum, which is more lightweight, in winter I'll go for the more heavy duty lipid, really just matching it with what your skin needs on the day. I think why these are so special is not only do you have that high dose of copper peptides, but you also have the delivery mechanism built in to make sure every single one of those peptides gets to exactly where it needs to be, which is why you get such quick results with both of these products."

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"I just love a lot of copper peptides. Actually, in my routine, I think the best of the best in copper peptides is this NIOD Copper Amino Isolate Serum 3. It's got technology in here that makes sure those copper peptides get to where they need to be in order to deliver maximum results. It's also beautifully hydrating. However, it comes with a higher price point, so whilst this is absolutely worth every penny, for those of you that are on a budget and maybe don't want to stretch to this price point, I hear you."

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"It also actually uses some now trademarked technology. They actually spent so much money on this technology, they went through the trademark process, which is kind of a sign that it's good, to get those peptides to where they need to be in the skin to give you maximum results. So I feel with the Neostrata product you're getting a good dose of peptides, but that technology really helps them work extra hard for you. I find it's a nice middle ground, it's not the cheapest product out there but it's also not super expensive, so it's a good mid price point, and one that I definitely love. The copper peptides in here are the ones that stand out, and whilst it doesn't have quite the same advanced blend of different firming peptides as the first two, it uses that technology to really get maximum results for the skin. So it's a really nice option, worthy a place in this video for sure."

Sincerely Miss Ash

195k subs · 3k devotees

✓Approved

"This is called Copper Amino Isolate Serum 3 and I've been using this one just as long as The Ordinary. They are basically the same thing, but this is more advanced because of the ingredients. NIOD is more advanced, which is why this brand is more money than The Ordinary. The ingredients that you see in some of the NIOD products you won't see in The Ordinary brand. I do feel like this provides quicker results, at least from my experience with this product. If I were to compare the two together, this one does give better results. I use it all the time, and I actually use this one more than NIOD just because it's quite pricey, so whenever there is a sale I do like to stock up on it, especially because of the price. It is phenomenal and it has a different texture, very thin like water, and it's also dark blue. Once you open it up you have about six months to finish it. It has a really nice texture that spreads across the skin. It's hydrating, it's not sticky or tacky either, and I've never experienced peeling. You can also use this every day, twice a day. So if you want to take your skin to the next level and you love your peptides, try copper peptides."

All 8 takes from Sincerely Miss Ash

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"This is truly a holy grail, and copper peptides is one of my favorite ingredients to incorporate on an everyday basis or several times through the week. I love copper peptides because peptides are great, I love peptides, but copper peptides truly take your skin to the next level. It firms the skin a little bit quicker, it also helps to stimulate collagen, it has wound healing properties to it, so it helps to speed up that healing process of the skin, just keeping your skin really healthy and radiant looking. I just love the glow that copper peptides gives my skin as well, especially this product. The texture is very thin, like water, it spreads so nicely, a little bit goes a long way, and it never peels, it's never sticky or tacky, it always sits great with other skincare products. This can be used every day, twice a day as well, but I will use this with other types of peptides, I will use this with vitamin C derivatives, not ascorbic acid but derivatives, and I'll also pair this up with hydrating repairing ingredients also."

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"This is the NIOD Copper Amino Isolate Serum 3, the 30 mil size. I love these two, so if I'm done with the Ordinary, I move on to the NIOD, and when I finish this I move back to the Ordinary. I like to alternate between these two the most, but I really do like this option, especially if I'm looking for something that is a little bit more moisturizing, that has that balmy effect. I really like the way that this applies to the skin also."

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"You would not believe the results that I have seen with this serum alone and I have been very consistent with this for over 2 years now pretty much and I am just absolutely in love and obsessed with this"

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"This one is a little bit more advanced in terms of the ingredients and also the texture of this is more like water this one spreads even better Across the Skin and your skin also absorbs this really nicely as well"

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"They are offering 50% off the copper Amino I slate serum and this is a serum that I talk about a lot here on my channel I use this one almost every day as well I do feel like this one is a little bit more effective"

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"I do find that this works a lot quicker but it's very comparable and similar to the ordinary you honestly can't go wrong with either one"

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"I'm really curious to see how this is going to work because it's been a while since I've used this and I can't remember how I liked it I can't remember if it pilled how it layered out with my skin care"

Darnell Cox | 50+ Healthy Aging Expert

54k subs · 263 devotees

✓Approved

"If you want the high-end version, the NIOD Copper Amino Isolate Serum 3. That'll cost you about 90 bucks, but it is great overall for skin health."

Dr Dray

2.67M subs · 26k devotees

~Mixed

"I find that the Nion serum is fine it works well as I said in my review on it but I don't know i don't enjoy using it as much i find it a bit more unwieldy texturally speaking"

Doctor Anne

55k subs · 778 devotees

✓Approved

"The last in the serum category is again repeated from the years before: NIOD Copper Amino Isolate Serum 3, hands down the copper peptide serum with the best texture I have tried."

Top Pick: copper peptide serum

All 3 takes from Doctor Anne

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"The last in the serum category is again repeated from the years before: NIOD Copper Amino Isolate Serum 3, hands down the copper peptide serum with the best texture I have tried."

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"The NIOD Copper Amino Isolate Serum 3 is one I have repurchased numerous times. Yes, it is very expensive, but I want copper peptides in my routine and the texture in this one is the most beautiful I have found, which is why I keep reaching for it."

So many skincare empties - Everything I used up in 2023 | Doctor Anne

"The NIOD Copper Amino Isolate Serum 3, even more expensive than the Estée Lauder one, is by far the best Copper Peptides Serum she has tried in terms of texture. The first one was PR, the two others she has purchased herself, that is how much she loves it."

Kelly Driscoll

90k subs · 4k devotees

✓Approved

"This is one of the very few expensive products where I would say if it fits your budget go for it I don't think that you will regret it it will show you results"

All 2 takes from Kelly Driscoll

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"This is one of the very few expensive products where I would say if it fits your budget go for it I don't think that you will regret it it will show you results"

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"This firms the skin it makes the skin feel you know when your skin just feels thicker but like in a good way right it feels thicker and firmer and more lifted"