Index / ZO Skin Health / Growth Factor Serum
ZO Skin Health

Growth Factor Serum.

ZO Skin Health Growth Factor Serum
Serums

About this product

A growth factor serum designed to plump fine lines, improve firmness, and support skin barrier function, formulated with plant-based stem cell extracts and botanical ingredients.

Best for

Mature skin
Serums

The Guru Index verdict

87%

Approved

✓Approved · 87%
2Reviewers
2Approved
0Mixed
0Skip

What the gurus are saying

Gurus who tested it praise how well it plumps fine lines and firms skin, with one expert calling it comparable to Botox in a bottle. The formula leans plant-based, with bluebell stem cells and ginseng extract higher on the ingredient list, though one guru noted the presence of silicone is a minor drawback. The consistent caveat: this is a luxury-tier investment, and experts suggest it makes the most sense for those already committed to a full medical-grade skincare routine that includes sunscreen and prescription treatments.
Synthesized from 2 expert reviews

Key actives & flags

Vitamin EPeptidesAlcohol-free

Full ingredients

Aqua/​Water/​Eau, Cyclopentasiloxane, Dipropylene Glycol, Propylene Glycol, Dimethicone, Glycerin, Dimethicone Crosspolymer, Dimethicone/​PEG-10/​15 Crosspolymer, PEG-12 Dimethicone Crosspolymer, Butylene Glycol, Dimethicone/​Vinyl Dimethicone Crosspolymer, Sodium Phosphate, Panthenyl Triacetate, Phospholipids, Magnesium Sulfate, Hydrolyzed Sericin, Ethyl Linoleate, Buddleja Davidii Meristem Cell Culture, Angelica Polymorpha Sinensis Root Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Lactobacillus/​Panax Ginseng Root Extract Ferment Filtrate, Disodium Acetyl Glucosamine Phosphate, Acetyl Tyrosine, Dimethiconol, Oleyl Alcohol, Proline, Fragrance (Parfum), Tocopherol, Beta-Glucan, Adenosine Triphosphate, Hydrolyzed Vegetable Protein, Sodium Chloride, Xanthan Gum, Phenoxyethanol

Where to buy

Every take, in full

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

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Darnell Cox | 50+ Healthy Aging Expert
Darnell Cox | 50+ Healthy Aging Expert
54k subs · 559 devotees
✓Approved
"This is Zo Skin Health, it's a growth factor serum. If you have money to burn, and I don't mean money to burn, if you prioritize your skin in such a way that it's like I don't care what it costs, I want the best of the best, Zo Skin Health everything that they produce is top of the line."
Top Pick: eye cream
All 4 takes from Darnell Cox | 50+ Healthy Aging Expert
What's in my Travel Bag?
"This is Zo Skin Health, it's a growth factor serum. If you have money to burn, and I don't mean money to burn, if you prioritize your skin in such a way that it's like I don't care what it costs, I want the best of the best, Zo Skin Health everything that they produce is top of the line."
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"I use that product daily I love it, you guys. That's like Botox in a bottle, just saying. I love it. It's the ZO Skin Health Growth Factor Serum, and how I use that is I use it actually as a moisturizer over the top of my retinoid at night, so I'll put on a retinoid and then I'll put that over the top of it. Amazing. Expensive, you have to, but you guys have to make sure if you're investing in these kinds of treatments, which, you know, it's an investment, I would 100% make you guys go out and buy your sunscreen, buy your medical-grade creams, buy your stem cell serums, all that stuff you need to be helping on the outside."
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"I really like the Zo Skin Health growth factor serum. It's super expensive, so I don't necessarily recommend everybody needs to use that post micro needling."
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"The best overall eye cream in my opinion is the ZO Skin Health Growth Factor Eye and it basically addresses everything so if you've got multiple concerns that's a good one but it's super expensive as well."
Dr. Somji Skin
Dr. Somji Skin
356k subs
✓Approved
"I love this product because I know that I'm going to send someone away and they're going to get the results. It really helps to plump out fine lines wrinkles, firming, it's very anti-aging. It's fantastic for hydration and helps to restore the barrier function as well. You've got these bluebell stem cell so it helps prevent future aging, you've got polymorphia sinensis root extract which helps calm and soothe the skin as well as has ginseng extract which helps with elasticity and firmness. If you actually look at the ingredients, yes we've got some silicone in there which is a little bit disappointing, but those root extracts come up a lot more higher on the list so it's a very natural, plant-based growth factor stimulating serum."
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