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Timeless

Matrixyl Synthe 6 Serum.

Timeless Matrixyl Synthe 6 Serum
Serums

About this product

A lightweight peptide serum containing Matrixyl Synthe 6, designed to address multiple signs of aging including fine lines, wrinkles, and loss of firmness while promoting collagen synthesis.

Best for

Mature skin
Serums

The Guru Index verdict

81%

Approved

Approved · 81%
2Reviewers
2Approved
0Mixed
0Skip

What the gurus are saying

Gurus consistently praise this serum for being hydrating, lightweight, and effective at firming skin and reducing fine lines with regular use. They highlight its versatility as a safe peptide option that pairs well with retinol and tretinoin without pilling or irritation. The consensus is that it's a strong choice for those targeting early to accelerated signs of aging, with some positioning it as an alternative for those who cannot tolerate vitamin C or retinoids.
Synthesized from 2 expert reviews

Key actives & flags

Hyaluronic acidPeptidesFragrance-freeAlcohol-free

Full ingredients

Water, Glycerin, Aloe Barbadensis, Sodium Hyaluronate, Benzyl Alcohol, Dehydroacetic Acid, Hydroxypropyl Cyclodextrin, Palmitoyl Tripeptide-38

Every take, in full

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Approved only Skip only Mixed only Hide sponsored
Approved
"I love their Matrixyl Synthe 6 serum."
All 4 takes from HotandFlashy
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"I love their Matrixyl Synthe 6 serum."
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"I apply my Timeless Matrixyl Synth 6 Serum, this is a peptide serum. The matrixyls help with varying signs of aging so they'll help with wrinkles, they'll help with discoloration, so help with all kinds of things. They're very hydrating."
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"The Timeless Matrixyl Synthe 6 Serum is a nice clear runny liquid. I just put on about a half a dropper of this, rub it along, and rub it all over my face and all over my neck. Matrixyl Synthe 6 is another peptide that hits six different signs of aging and it helps your skin to produce more collagen and helps to reduce your wrinkles."
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"The second thing that I put on after that at night is my Timeless Matrixyl Synthe 6 Serum. This is another Matrixyl but this one helps with six different signs of aging. This one is supposed to help with synthesis of collagens types 1, 3, 4, fibronectin, laminin, and hyaluronic acid. So this is another great peptide that has been shown to work in the skin. Very lightweight, fluid serum that's easy to apply."
Approved
"This is a peptide serum that addresses fine lines and wrinkles and to help firm the skin. This is also very hydrating as well, and it could be paired with retinol, with tretinoin, you can pair this up with a lot of things. I really like this one more so over the Timeless Matrixyl 3000. If you're starting to experience more accelerated signs of aging, loss of firmness, fine lines, then I would say go with Matrixyl Synthe 6. I think it works a lot better from my experience with it. I do have a backup so I will be continuing with this for sure."
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All 4 takes from Sincerely Miss Ash
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"Matrixyl Synthe 6 is more for accelerated signs of aging. You are starting to develop fine lines and wrinkles, then I would say go with Synth 6. This one from Timeless is exceptional, super hydrating, it never pills with other skin care products. You can use this paired up with your retinol at night time or tret, you can also use this in the morning if you wish, up to twice a day. Once a day is honestly sufficient enough, but if you want to use this twice a day go for it, it's safe enough to do so. It's a peptide, it's not going to be irritating on the skin at least for most people, and it's a great product to use to firm the skin. It can also help to stimulate new collagen as well. If you're starting to see signs of aging, that sagging of the skin, go with the Matrixyl Synth 6 because I truly believe that you will see better results with this one."
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"I really like the Timeless Matrixyl Synthe 6 Serum. This is a great peptide serum to incorporate before your tretinoin or of course before your retinal because peptides really help to firm the skin and they can really give more of that youthful look to the skin with consistent use. I love pairing up peptides with tretinoin and I just think that is one of the best pairings you can do for signs of aging and to firm up the skin."
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"This is a peptide serum that addresses fine lines and wrinkles and to help firm the skin. This is also very hydrating as well, and it could be paired with retinol, with tretinoin, you can pair this up with a lot of things. I really like this one more so over the Timeless Matrixyl 3000. If you're starting to experience more accelerated signs of aging, loss of firmness, fine lines, then I would say go with Matrixyl Synthe 6. I think it works a lot better from my experience with it. I do have a backup so I will be continuing with this for sure."
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"I love the Matrixyl Synthe 6. I feel like this is definitely underrated and I think you should try this at least once. This is a great alternative option if you're someone that can't use vitamin C or retinol, this would be like the next best thing to use to target signs of aging. You can use this on its own and use this every day twice a day if you wish to, or you can use this prior to tretinoin or retinol."
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