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Timeless

Matrixyl Synthe'6 Serum.

Timeless Matrixyl Synthe'6 Serum
Serums

About this product

A lightweight peptide serum containing Matrixyl Synthe'6, designed to address multiple signs of aging including fine lines, wrinkles, and loss of firmness while providing hydration.

Best for

Mature skin
Serums

The Guru Index verdict

82%

Approved

Approved · 82%
3Reviewers
3Approved
0Mixed
0Skip

What the gurus are saying

Gurus found this peptide serum helps firm skin and reduce wrinkles, with one expert noting it supports collagen production and addresses multiple aging concerns. The formula is lightweight and hydrating, and those using tretinoin or retinol may want to apply it first since peptides pair well with these actives. Most reviewers suggest using it once daily, though it can be applied twice daily if preferred, and it's gentle enough for those who can't tolerate vitamin C or retinoids.
Synthesized from 3 expert reviews

Key actives & flags

Hyaluronic acidPeptidesFragrance-freeAlcohol-free

Full ingredients

Water, Glycerin, Aloe Barbadensis, Sodium Hyaluronate, Benzyl Alcohol, Dehydroacetic Acid, Hydroxypropyl Cyclodextrin, Palmitoyl Tripeptide-38

Every take, in full

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Approved only Skip only Mixed only Hide sponsored
Approved
"This Matrixel Sin 6 serum contains 2% Matrixel Sin 6. And this one is also kind of a double duty product because you do get the CoQ10 in there."
All 5 takes from HotandFlashy
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"I love their Matrixyl Synthe'6 serum."
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"I apply my Timeless Matrixyl Synthe'6 Serum, this is a peptide serum. The matrixyls help with varying signs of aging so they'll help with wrinkles, they'll help with discoloration, so help with all kinds of things. They're very hydrating."
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"The Timeless Matrixyl Synthe'6 Serum is a nice clear runny liquid. I just put on about a half a dropper of this, rub it along, rub it all over my face and all over my neck. Matrixyl Synthe'6 is another peptide that hits six different signs of aging and it helps your skin to produce more collagen and helps to reduce your wrinkles."
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"The second thing that I put on after that at night is my Timeless Matrixyl Synthe'6 Serum. This is another matrixyl but this one helps with six different signs of aging. This one is supposed to help with synthesis of collagens types 1, 3, 4, fibronectin, lamins, and hyaluronic acid. So this is another great peptide that has been shown to work in the skin. Very lightweight, fluid serum that's easy to apply."
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"This Matrixel Sin 6 serum contains 2% Matrixel Sin 6. And this one is also kind of a double duty product because you do get the CoQ10 in there."
Approved
"Timeless makes a stronger one than this, and it's called Timeless Skincare Matrixyl Synthe'6 Serum."
Approved
"This is a peptide serum that addresses fine lines and wrinkles and to help firm the skin. This is also very hydrating as well and it could be paired with retinol with tretinoin you can pair this up with a lot of things. I really like this one more so over the Timeless Matrixyl 3000. Matrixyl 3000 is very similar to this, it's peptides, but Matrixyl 3000 is more for those that are starting to see early signs of aging or maybe you haven't seen it yet but you want to prevent it. The Matrixyl 3000 would be the serum that I would go with if you're starting to experience more accelerated signs of aging, loss of firmness, fine lines, then I would say go with Matrixyl Synthe'6. I think it works a lot better from my experience with it. I do have a backup so I will be continuing with this for sure."
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All 5 takes from Sincerely Miss Ash
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"I love Matrixyl Synthe'6 because it really does firm the skin."
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"Matrixyl Synthe'6 is more for accelerated signs of aging. If you're starting to develop fine lines and wrinkles, I would say go with Synthe'6, and this one from Timeless is exceptional. It's super hydrating, it never pills with other skincare products. You can use this paired up with your retinol at night time or tretinoin, or you can also use this in the morning if you wish, up to twice a day. Once a day is honestly sufficient enough, but if you want to use this twice a day, go for it. It's a peptide, it's not going to be irritating on the skin, at least for most people. It's a great product to use to firm the skin. It can also help to stimulate new collagen as well. If you're starting to see signs of aging, that sagging of the skin, go with the Matrixyl Synthe'6 because I truly believe that you will see better results with this one."
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"I really like the Timeless Matrixyl Synthe'6 Serum. This is a great peptide serum to incorporate before your tretinoin or of course before your retinal because peptides really help to firm the skin and they can really give more of that youthful look to the skin with consistent use. I love pairing up peptides with tretinoin and I just think that is one of the best pairings you can do for signs of aging and to firm up the skin."
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"This is a peptide serum that addresses fine lines and wrinkles and to help firm the skin. This is also very hydrating as well and it could be paired with retinol with tretinoin you can pair this up with a lot of things. I really like this one more so over the Timeless Matrixyl 3000. Matrixyl 3000 is very similar to this, it's peptides, but Matrixyl 3000 is more for those that are starting to see early signs of aging or maybe you haven't seen it yet but you want to prevent it. The Matrixyl 3000 would be the serum that I would go with if you're starting to experience more accelerated signs of aging, loss of firmness, fine lines, then I would say go with Matrixyl Synthe'6. I think it works a lot better from my experience with it. I do have a backup so I will be continuing with this for sure."
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"I love the Matrixyl Synthe'6 since it's definitely underrated and I think you should try this at least once. You can use this prior to tretinoin or retinol, or you can just use this on its own and use this every day twice a day if you wish to. This is also another great alternative option if you're someone that can't use vitamin C or retinol, this would be like the next best thing to use to target signs of aging."
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