A lightweight serum containing 10% argireline (acetyl hexapeptide-8), a peptide designed to reduce the appearance of expression lines by limiting muscle contraction.
Argireline delivers visible softening of fine lines and expression wrinkles, but not the deep muscle paralysis that injectable Botox achieves. Most gurus praise it as an affordable, lightweight option with instant plumping results, though a minority found no visible difference even after sustained use, and a few experienced irritation or dryness. Consistency matters: you need to apply it regularly to see and maintain results, and it works best as a spot treatment on thin-skinned areas like the eyes and forehead.
Synthesized from 15 expert reviews · most recent take September 2026
"The Ordinary Azureine, which people refer to as Botox in a bottle for its ability to plump out and reduce the depth of wrinkles, can be used beforehand to further enhance the results when paired with the PDRN eye cream. They do pair really, really well together."
All 27 takes from Mad About Skin
PERFECT ANTI AGING - How To Use Argireline (Botox In A Bottle)
"I personally love this super affordable serum. It really just hones in on Argireline as the standout star performing ingredient, but doesn't offer a whole lot more. [...] Whether you opt to continue with The Ordinary Argireline Solution for its simplicity and affordability or go for a more advanced peptide option, [...] it really doesn't matter. Do what works for you."
"This is The Ordinary Argireline Solution. Argireline is a very specific peptide known as Botox in a bottle for its ability to immediately remove fine lines and wrinkles. It's amazing. And this is a standalone peptide serum that I would genuinely invest in. I have done for years."
Its Official: BOTOX IN A BOTTLE JUST LEVELLED UP - Argireline Serums (6 Year Update)
"This is great if you just want to experiment with this ingredient. If you just want something super simplistic, super affordable that you can just slot into your skincare routine and get those great results, you honestly cannot beat this. There's not much else in here. You got your Argireline and some hydrating base ingredients and that's pretty much it. But that's okay. Dab a little of this on those areas where you have that dynamic fine lines and wrinkles. I'm talking about the crow's feet, the laughter lines, the elevenses. Dab it onto these areas and then apply the rest of your skin care afterwards. You'll get the benefits without really noticing that you're using a whole lot more product. It won't break the bank and it's just really, really accessible. The Ordinary led the way when it came to Argireline and like I say, really disrupted the anti-aging industry in a way that I think we're all benefiting from as we come into 2026. I'll be forever grateful to them for this product and the way they approached anti-aging and yeah sometimes the OG and the affordable it's just the best and this really really is a wonderful product."
BEST ANTI AGING SERUM 2024 - Which Botox In A Bottle Serum Wins
"The Ordinary is budget friendly and has a known concentration of that key ingredient, 10%. This is fairly simplistic, it is just argireline, doesn't really have anything else going on alongside it other than some humectants which help to hydrate and plump out the skin. This is fabulous and I think a great place to start if you're on a budget, you want to start with argireline, or you want something super simplistic to just slot into your skincare routine. The Ordinary is a really great option."
WORLDS BEST ANTI AGING - Growth Factors + Argirline + Matrixyl = Botox In A Bottle
"Argireline is amazing. I've been using it for years and I would never be without it because it actually gives you instant results. A lot of peptides you have to invest now for those long-term payoffs, which I think is great, but who doesn't want a quick win, a quick boost to their skin confidence the second you apply the product. That's really what Argireline offers. [...] The Ordinary Argireline Solution 10% is a basic but really effective formulation that I've used on and off for years. [...] Apply it to the areas where you want to target, so for me this is the crow's feet and the laughter lines. Put a little on these areas and then let it sink in for 30 seconds, let it get into the skin and start to do its work."
ANTI AGING BREAKTHROUGH - The Best Peptide Serums For Anti Aging
"You can also, of course, go for the original Argireline, which was from The Ordinary. The Ordinary as a brand do everything super inexpensive and they really popularize the use of Argireline with their Argireline 10% serum. Great concentration, super easy to apply and doesn't break the bank. Really, really great."
Ultimate BOTOX IN A BOTTLE SKINCARE ROUTINE - My Morning Anti Aging Routine
"The reason I filming this today is it's exactly 2 years to the day that I first shared my thoughts on this anti-aging Duo the ordinary aurine solution known as Botox in a bottle"
THE ORDINARY SALE - Top 10 The Ordinary Products
"If you're going to just buy one thing from The Ordinary, let it be The Ordinary Argireline Solution. I've gone on about this endlessly for the past four years. [...] The Ordinary Argireline Solution is amazing. It's known as Botox in a bottle online, but it truly is a transformative instant anti-aging wonder. You just dabble a little of it where you have dynamic fine lines and wrinkles caused by movement, you know, the laugh lines, the elevens, the crows feet, the jawline. Apply it and within just a couple of minutes you'll notice that those wrinkles are really diminished in their depth and the skin looks smoother. It has some long-term benefits too. [...] It is just a wonder, wonder, confidence boost in a bottle is what I call it. [...] It's still the best of the best even four years on from me first discovering it."
The End Of PEPTIDES SERUMS? - Products Are Vanishing (Heres Why)
"The Ordinary Argireline Solution, for example, a great peptide but it is just one, a serum which focuses down on one single peptide which of course has limited benefits because it's just one peptide."
ULTIMATE MORNING SKINCARE ROUTINE - Botox In A Bottle Anti Aging Results
"The Ordinary Argireline Solution is known as Botox in a bottle, super popular. They've sold over 5 million units in the last year allegedly. It's one of my two favorite serums when it comes to anti-aging."
Best Ever MORNING SKINCARE ROUTINE 2026 - Instant Glowing Skin
"I'm using the one by The Ordinary, which works really, really well for me. This you just dab on the areas where you have the appearance of fine lines and wrinkles. So, for me, this is going to be the crow's feet, you've got the 11s, and you've got the laughter lines. Dab a little of this on and kind of let it get to work."
$20 BOTOX IN A BOTTLE DUO - 3X Better Anti Aging
"The Ordinary Argireline is a single peptide which is often affectionately known as Botox in a bottle because whilst it's not the same as an injectable Botox treatment, it does work and has a similar mechanism of action. It actually immediately reduces the depth of fine lines and wrinkles and one such study actually showed it reduces that depth by 17% instantly. This is a real game changer if you're someone that likes quick wins and it works best on fine lines and wrinkles caused by movement. Usually the crow's feet, the 11's and the laughter lines."
REMOVE WRINKLES FAST - Best Botox In A Bottle ( Argireline ) Serums
"I think it's fair to say that argireline is hands down my all-time favorite ingredient in skincare and I would never be without it in my routine. However, I no longer reach for this particular serum because I've discovered some other products that contain argireline alongside some other amazing ingredients often giving you enhanced benefits at the same affordable price point."
ULTIMATE BOTOX IN A BOTTLE Eye Routine - 3 Step Eye Lift
"If you want to just do a really quick 30 second application you absolutely can reach for The Ordinary Argireline Solution 10% and use that in place of these the two are kind of interchangeable. I find you get the best results from the pads but if you're in a hurry and you just want a quick win the Ordinary Argireline will never steer you wrong."
BEST EVER ANTI-AGING RESULTS - Next Level Botox In A Bottle
"Argireline is a single peptide and this peptide has actually been studied and proven if used consistently to reduce the depth of any wrinkles that you see by up to 17%. Now 17% is actually a really great result especially when you consider all those lotions and potions we've been using over the years that really haven't done a whole lot. If you can get some guaranteed results from reaching for an affordable drugstore product like that, why not? It just seems like a no-brainer to incorporate into your skincare routine. [...] The Argireline will target those dynamic fine lines and wrinkles, the ones caused by movement. This is why it works great on the crow's feet around the eyes. [...] I use it twice a day which I think is essential to get the best results, morning and evening. I'll use it early on into my serum so I'll cleanse the skin and then these will be the first serums that I actually apply. [...] I take a couple of drops of the Argireline and apply them to the areas where I have dynamic fine lines and wrinkles, the crow's feet, the laugh lines."
Official - WORLDS BEST ANTI AGING SERUM (5 Year Update - The Ordinary Argireline Solution)
"Apply your Argireline solution straight after cleansing, [...] and then go on with the rest of your skincare routine. That way, this little Botox in a bottle gem is really close to the skin, absorbing and getting to work in that 10-minute gap. So when you finish your skincare routine, you'll already be seeing the difference. Over the last 5 years, I've experimented with a lot of different Argireline solutions. [...] The Ordinary Argireline Solution 10% is still a wonderful, wonderful product. If you want to keep it super inexpensive and get your Argireline fix on a budget, you can pick this up for around £10, something like £11. It doesn't break the bank and it definitely delivers that Argireline hit and those immediate anti-aging results."
Next Level BOTOX IN A BOTTLE SERUM - Best Anti Aging Serum
"I've been a huge advocate of using these two products together, the Ordinary Argireline and the Ordinary Matrixyl together. You get those long-term collagen boosts and those short-term wrinkle reductions, which is why this for me has been a Holy Grail."
SKINCARE PRODUCTS I USE EVERY DAY - Anti Aging Essentials
"I actually use this alongside The Ordinary Argireline Solution 10% which I use every single day in my skincare routine for that like perfect reduction in fine lines and wrinkles, especially around the crow's feet and the 11s. The Argireline will work, it's called Botox in a bottle, but it will work to smooth out dynamic fine lines and wrinkles. The results are temporary but I think we all love a quick fix to boost our skin confidence on a morning and get us feeling our skin best. Since I discovered this, which is relatively recently, I've never skipped a day. My under eye in particular absolutely loves it."
SUPERCHARGED ANTI AGING - The Perfect Peptide Serum
"The one that I go back to time and time again is The Ordinary Argireline Solution 10%. I love it because it's a beautiful lightweight formula. It's really water in its consistency, so it's easy to layer and pair in a routine. It's super inexpensive, and they're transparent about the concentration. 10% is a sky high amount, so you're going to get some next level results. And it's just a really dependable serum that I've used consistently for 5 years, and I can't see myself being without. Argireline is the one exception to the rule that I would say of avoid single peptide formulations. I think you'll get better results elsewhere with the exception of Argireline, which honestly I think as a standalone peptide really, really delivers."
Its Official - PEPTIDE SERUMS JUST CHANGED FOREVER (Peptide Flooding)
"You need a standalone Argireline solution. I'm using the Ordinary one because I find that this is the most cost effective. It's the easiest. It's also the most simplistic formulation. You really want these products that you choose to focus down on peptides, not have a load of other additional actives in them because that's when you could start seeing sensitivity and irritation. So, kind of go simplistic. Just focus down on products that really just use those peptides to maximum effect. You want to dab this on the areas where you need it. This is what really delivers that dynamic fine line and wrinkle reduction. Talking about the crow's feet, the laughter lines, and the elevenses. Dab a good dose of this on those areas and wait sort of like 20 seconds for it to sink in and do its work."
This Is The Ultimate Anti-Aging Serum - BOTOX IN A BOTTLE BATTLE
"When you think of all the money you spent on those hero anti-aging creams that have really delivered nothing, at least with this, which is super affordable, you're getting a guaranteed result. I think it's worth every single penny. It now costs around £8 here in the UK. [...] Set your expectations clearly and slot this into your skincare routine to get some instant hydration, some long-term anti-aging, and some proven results too. I honestly think this is a product that I'm happy to allow to call themselves Botox in a bottle, knowing you are getting some proven results. [...] I use this every single day, and for me The Ordinary Argireline line is the best because of that price point. [...] The price point and the accessibility just means that I go back to The Ordinary time and time again, and my skin loves it."
THE ORDINARY SALE 2025 - Top 10 The Ordinary Serums
"The Ordinary Argireline Solution, affectionately known as Botox in a bottle on the online skincare community. It just really works. Studies show this actually reduces the depth of fine lines and wrinkles by 17% on application. You don't have to wait around. This isn't an investment for those long-term payoffs. This is just a quick win. I love it. It's a single peptide serum, but you can use it alongside other peptide serums that you might have. And I use it in a targeted way. I just put a little on the crow's feet and on the laughter lines every morning, and I definitely see a difference. [...] I don't use a lot because I use it in a targeted way. So, two will last me that full 12 months. If you use more of this, you use it on more areas, maybe use it twice a day, which is absolutely fine. You might want to buy a few more. But for me, two is all I need. That'll see me through these 12 months. [...] Every year I mention it, still going strong and I absolutely love it."
Worlds Best BOTOX IN A BOTTLE - 3X Better Anti Aging
"The Ordinary Argireline 10% is a great option. This is kind of known as Botox in a bottle online because it immediately minimizes the appearance of fine lines and wrinkles. One study actually showed that if used topically on the skin, can reduce the depth of wrinkles by 17% on application. 17% isn't to be sniffed at when it comes to wrinkle reduction, which is why I think so many people love this, especially because it's super affordable. You're going to want to apply this onto the areas where you have specific fine lines and wrinkles that you want to target. For me, this is the crows feet, it's the laughter lines, and the lines between the eyebrows. Put a dose of this on these areas. That's going to get to work targeting those wrinkles that are caused by movement. You could also use this on the neck if you just want to lift and tighten things a little bit. Apply it to these areas and allow it to sink in for like 30 seconds to start to get to work. That kicks things off by really helping to minimize some of those dynamic fine lines and wrinkles."
Best Ever ANTI AGING SKINCARE ROUTINE - Boost Skin Collagen By 25%
"You can absolutely go in with The Ordinary Argireline, which used to be my favorite, it still works really well, but that's one peptide. Why settle for one when you can have a plethora of different peptides in high concentrations in a product like this? It's the next level and it's the same price as The Ordinary, so to me that's just a no-brainer."
ULTIMATE KOREAN SKINCARE ROUTINE 2023 - Using Best Korean Skincare
"I've experimented with a lot of Korean eye creams which is usually the step I'll apply straight after my cleanser, but honestly my absolute favorite at the moment is to combine The Ordinary Argireline Solution 10% with this"
SKINCARE DUO THAT TRANSFORMED ANTI AGING - 5 Years Later
"The Ordinary Argireline Solution 10% is amazing at targeting fine lines and wrinkles, it has an immediate impact so you get those quick wins. More studies have gone into Argireline in the last five years proving how effective it is, and used consistently it can reduce the depth of fine lines and wrinkles by seventeen percent, which is a really good and noticeable reduction from just one product. I still stand by the Ordinary Argireline Solution 10% as one of the very best single peptides on the market."
Worlds Most Effective SKIN FIRMING HACK - $10 Secret For Firmer Skin
"The Ordinary Azureine, which people refer to as Botox in a bottle for its ability to plump out and reduce the depth of wrinkles, can be used beforehand to further enhance the results when paired with the PDRN eye cream. They do pair really, really well together."
"This is the Ordinary Argireline Solution 10%. If you're somebody that doesn't get Botox, this is good for you, but also if you're somebody that does get Botox, this is good for you too, because it will shrink your pores a little bit when you use it on your face."
All 4 takes from Darnell Cox | 50+ Healthy Aging Expert
Over 30 and ready to master the ultimate MORNING skincare routine? 🎙️Join me for an IG Live Show
"This is argireline solution by The Ordinary. Very cheap, very inexpensive. It's less than 10 bucks. But this is like Botox in a bottle. So, if you're somebody [...] that doesn't want to do Botox or you're wanting to soften like some of the bands in your neck, [...] this is something that's really good. [...] It's a signaling peptide that signals for your muscles to relax a little bit."
Over 30 and ready to master the ultimate skincare routine? 🎙️Join me for an IG Live Show where
"The Ordinary Argireline 10% is a neurotransmitter-inhibiting peptide, like Botox in a bottle. It's always going to be the cost effective version, and I don't mean cheap as in ineffective, I mean it's cost effective."
Your neck is snitching on you
"This is an argireline peptide, a neurotransmitter inhibitor peptide that relaxes the muscles causing the neck bands. For a friend who does not want to do Botox on the neck bands, The Ordinary makes a very cheap argireline peptide that will naturally soften those bands."
10 Step Skincare Routine for “Glass Skin”✨ 🎙️On yesterday‘s live show I went over skincare 101
"This is the Ordinary Argireline Solution 10%. If you're somebody that doesn't get Botox, this is good for you, but also if you're somebody that does get Botox, this is good for you too, because it will shrink your pores a little bit when you use it on your face."
"Another recommendation is the Ordinary Argireline Solution 10%. This is the one that works kind of like Botox works on the expression lines."
All 2 takes from Dr. Aleksandra Brown
Best Anti-Aging Ingredients Ranked by a Dermatologist
"Another recommendation is the Ordinary Argireline Solution 10%. This is the one that works kind of like Botox works on the expression lines."
Peptides in Your 40s: Which One Do You Actually Need? | Dermatologist Explains
"The Ordinary's 10% Argireline is only about $10, a really simple water-based serum with the peptide at 10% concentration aimed right at movement lines, so you apply it to the areas where you actually crease, like your forehead, between your brows, or crow's feet. Argireline is okay, it's good for expression lines if you don't want to do Botox or if you're trying to extend your in-between Botox times, you can consider adding it, but personally I really struggle finding a spot for it because I'm not going to get rid of my vitamin C, my retinoid, and my sunscreen, and by the time you layer a couple of different serums plus a moisturizer, that's a lot of layers already."
"I gave this such a fair shot. Multiple bottles, consistent use, I committed to the cause, but I'm still unconvinced. I know people absolutely swear by this product. Theoretically, it makes sense. The peptides are meant to soften expression lines. But for me, I just never saw enough of a difference. And at this point in my skin care life, if I go through multiple bottles of something, I want to at least feel that it's working. I don't want to wonder about it. So this one just quietly exited the building."
All 5 takes from Skin Obsessed Mary
I Didn’t Repurchase Most of These
"I gave this such a fair shot. Multiple bottles, consistent use, I committed to the cause, but I'm still unconvinced. I know people absolutely swear by this product. Theoretically, it makes sense. The peptides are meant to soften expression lines. But for me, I just never saw enough of a difference. And at this point in my skin care life, if I go through multiple bottles of something, I want to at least feel that it's working. I don't want to wonder about it. So this one just quietly exited the building."
My Winter MORNING Skincare Routine for Mature Skin
"This product in particular has a very watery consistency, which I have to say is not my favorite. I find these really runny products a little hard to control on application. So I spot apply this to my crow's feet, my forehead, my levenses, and even my nasolabial folds. Now, I am on my second bottle, but I have to be honest. I'm not fully convinced that it's doing a huge amount. Now, I'm giving it a proper go, and I mean, and for the price point, why wouldn't you? I'm just not sure if I'm going to go in for a third bottle."
My Everyday Winter EVENING Skincare After 50
"I'm using the peptide by The Ordinary. It is the Argireline and that's because it's designed to soften dynamic expression lines by limiting muscle contraction. I mentioned in the morning video that it has this very watery texture which I really find hard to work with. I'm only spot applying this to areas of movement like the forehead, the eleven's, the crow's feet, and around my mouth. I'm not sure I will continue once this bottle's up, but we'll see how it goes."
❄️ Morning Winter Skincare Routine for Mature, Hydrated, Glowing Skin
"This is the 10% Argireline Solution by The Ordinary. I actually bought this nine months ago and it just sat there, and I only just started using it recently. This product is specifically designed to target dynamic lines and wrinkles, so those lines that happen here and the crow's feet around here. I'm a bit more generous with it. I'm also kind of doing it around the lip lines, the marionette lines, and even down on the neck. It's super watery, which means it's really hard to control, but it's really affordable. You know, it's early days, but we'll see."
❤️ Answering YOUR Top Questions about Skincare, Beauty & Me ❤️
"The Ordinary Argireline is a peptide that's designed to help sort of relax the muscles. They say it's a Botox effect, it is not, but it's the same idea. This is great, I'm making my way through it, it's quite interesting."
"The Ordinary also has a 10% Argireline Solution which is targeted for fine lines at a very affordable price."
All 2 takes from Dr. Shereene Idriss
How to Treat Under Eye Wrinkles from a Dermatologist! | Dr. Shereene Idriss
"The Ordinary has one at 10% for not a lot of bucks, you cannot beat that. It is their Argireline peptide complex. Only works as long as you use it, you're not gaining any sort of long-term benefit by using it, it's not promoting collagen in the long run, it is only working as you're using it. So I would use it even morning and evening, evening before doing your makeup and going out, morning obviously for the full day. Would I do it at night to go to sleep probably not, but you can use it every single day to minimize deeper line formation over time."
Not All Peptides Are Equal — Dermatologist Explains What’s Worth the Hype! | Dr. Shereene Idriss
"The Ordinary also has a 10% Argireline Solution which is targeted for fine lines at a very affordable price."
"The Ordinary Argireline Solution 10% is toted as Botox in a bottle, which is a pretty much misleading product claim. A dermatologist quoted in a Vogue article said that [...] do you really think something that you apply topically is going to be able to give you the same type of results as something like Botox, which is injected deeper into the skin's layers and works by blocking nerve signals to muscles."
"The Ordinary Argireline Solution is a very affordable one. This specific type of peptide, Botox in a bottle, [...] will target muscle contraction and help prevent that from [...] firing quite so hard, and that is supposed to lessen the amount of wrinkles on your face. [...] Peptides can be really helpful if you are someone who does not use injectable Botox because this is another way, obviously not as effective, but you're not injecting something so you can still get some of those benefits without injection."
All 2 takes from The Budget Dermatologist
Improve Forehead Wrinkles Without Botox | 3 At-home Tips!
"The Ordinary Argireline Solution 10% is a very affordable budget option. It contains argireline, which is the peptide known as Botox in a bottle. You apply this to the skin as part of your skincare routine and it's going to absorb into your skin and soften your muscular contraction and lessen how severely your wrinkles can be formed. You can use it morning or night in your routine. I love to use peptides, and I love to use this one in the morning so I have my topical skincare product that is attacking the muscular movement."
Improve Wrinkles Without Botox! | What I’m Currently Doing In My Skincare Routine
"The Ordinary Argireline Solution is a very affordable one. This specific type of peptide, Botox in a bottle, [...] will target muscle contraction and help prevent that from [...] firing quite so hard, and that is supposed to lessen the amount of wrinkles on your face. [...] Peptides can be really helpful if you are someone who does not use injectable Botox because this is another way, obviously not as effective, but you're not injecting something so you can still get some of those benefits without injection."
"I'm using it on my leavens and around my crow's feet. The instructions on this are to use it twice a day. I've only been using it once a day so I think I'm going to bump it up to twice a day. I'm going to use it morning and evening with my serums. I am going to continue with this and we'll see if it does help my Botox last a little bit longer and maybe soften some of my wrinkles like my crow's feet and my leavens."
"Argireline is supposed to be like Botox in a bottle. People ask me about argireline all the time and if it works, and my general feeling about it is that no, it's not going to be Botox in a bottle. But I've heard from a lot of you guys who say that you use it and you think it does help, and especially people who use Botox say that it helps it to last longer. So I've been trying this lately. I haven't been using it all over my face, I just kind of use it as a spot treatment around my crow's feet, under my eyes, and on my forehead. Can't say I'm seeing any huge difference because of course I do have some Botox in my face right now."
Skincare Hits + Misses! NEW Skincare I've Been Trying...
"I'm using it on my leavens and around my crow's feet. The instructions on this are to use it twice a day. I've only been using it once a day so I think I'm going to bump it up to twice a day. I'm going to use it morning and evening with my serums. I am going to continue with this and we'll see if it does help my Botox last a little bit longer and maybe soften some of my wrinkles like my crow's feet and my leavens."
"Yes this is a nice product if its key consistency if the way the ingredients go only this one has more thickness this is absolutely like water why is it better even I could not understand why this is better but the only reason that I could get around it is the quality of hexapeptide 8"
Translated from the guru's original language.
Top Pick: argireline solution
All 4 takes from Nipun Kapur
Better than Botox in a bottle? Find out! Review of Airgirline by Asterwood, Skin Deva and Ordinary
"I have not yet found anything that is better than the 10% Solution by The Ordinary, and the day I find something better, the day I find an upgraded version that is better, 100%, after I test it out I will make a video about it."
Ordinary Versus Minimalist | Top 5 products from the Ordinary | Review of Ordinary Peptides
"For its price for its quality is one of the best that you can get in the market"
Translated from the guru's original language.
Botox in a Bottle: How to Reduce Forehead Wrinkles | Anti-Aging Skincare Tips | Nipun Kapur
"Yes this is a nice product if its key consistency if the way the ingredients go only this one has more thickness this is absolutely like water why is it better even I could not understand why this is better but the only reason that I could get around it is the quality of hexapeptide 8"
Translated from the guru's original language.
How get rid of wrinkles | My anti aging night routine | Overnight Botox | Nipun Kapur
"The Argireline from The Ordinary is very thin it's like water"
"If you're looking for a 10% option that is strictly just Argireline, I would say look into this and it's also really affordable. You're getting 30 ml of product and there is a 12-month shelf life with this. [...] A lot of people swear by this and truly this does work. There was a time where I was really consistent with this and it really did help to soften some of the lines around my eyes, so crow's feet. You can use this underneath the eyes if your skin allows you to. [...] The skin underneath and around the eyes is so thin and delicate so we should always be cautious, but when I was testing this I was mainly using this as an under-eye serum and it worked really well. [...] There was a thing going around that Argireline can cause sagging of the skin. I have personally never experienced this. There was a time where I was really consistent with this serum so I personally never saw that. I [...] can tell you right now I never experienced such a thing."
All 3 takes from Sincerely Miss Ash
PRODUCT'S I'VE USED UP | WOULD I REPURCHASE? BEAUTY EMPTIES 2023
"I have been using this quite a bit on and off for several years and I do think this is lovely. It's very thin and lightweight, it absorbs into your skin so nicely, but I do feel like you need to be very, very consistent with this before you see results. This is great even as a spot treatment, so if you just want to use this as that eye serum or to treat your forehead lines, your levens, nasolabial folds, or just put it all over your face and your neck and chest, you can also do that. And again, I do like it, but the copper peptide serum or the multi-peptide plus hyaluronic acid serum contain multiple peptides and work quicker because there's more than one type of peptide in that formula."
BOTOX IN A BOTTLE - SKINCARE PRODUCTS THAT MIMICS BOTOX WITHOUT INJECTABLES | RESULTS GUARANTEED
"If you're looking for a 10% option that is strictly just Argireline, I would say look into this and it's also really affordable. You're getting 30 ml of product and there is a 12-month shelf life with this. [...] A lot of people swear by this and truly this does work. There was a time where I was really consistent with this and it really did help to soften some of the lines around my eyes, so crow's feet. You can use this underneath the eyes if your skin allows you to. [...] The skin underneath and around the eyes is so thin and delicate so we should always be cautious, but when I was testing this I was mainly using this as an under-eye serum and it worked really well. [...] There was a thing going around that Argireline can cause sagging of the skin. I have personally never experienced this. There was a time where I was really consistent with this serum so I personally never saw that. I [...] can tell you right now I never experienced such a thing."
ANTI-AGING SKINCARE ROUTINES ON A $60 BUDGET | MORNING & NIGHTTIME | AFFORDABLE AND EFFECTIVE!
"I really love Argireline. A lot of people say this is Botox in a bottle. It really helps to soften fine lines, so if you have forehead lines, your lemon lines, crow's feet, nasolabial folds, this is honestly great to apply all over your face, all over your neck, and all over your chest. It has that watery texture so you never have to worry about pilling. This layers up with everything so nicely without issues, and also it is very lightweight and spreads nicely. I love the formula, this is really effective as well. This really is the peptide that I highly recommend, especially if you're on a budget."
"I don't dislike this product, I've loved it for a very long time now, but like I said in my products versus ingredients video, I'm setting this one aside. I'm not a loyalist to it, so I'm trying an Indeed Labs peptide product with a similar neurotransmitter inhibiting mechanism instead."
All 3 takes from AliceintheRabbitHole
The Ordinary Argireline Peptide: WHY it’s Compared to Botox
"I decided to buy the ordinary's argireline solution because it's inexpensive, under ten dollars, and I feel like it's the most popular product containing argireline, at a zero point five percent concentration. I don't want to spend a lot of money on something that isn't scientifically proven to work like Botox, so the ordinary gives me a budget friendly option. I'm happy with the hydration, and honestly I do feel I've seen a bit of inhibition, not a full loss of movement, but something has improved about how frowny my face used to be. That said, I have to be honest that this could just be a placebo effect since I'm not running a blind study on myself, and it's also very watery, which makes it kind of hard to work with."
Products I'm QUITTING (& their replacements!)
"I don't dislike this product, I've loved it for a very long time now, but like I said in my products versus ingredients video, I'm setting this one aside. I'm not a loyalist to it, so I'm trying an Indeed Labs peptide product with a similar neurotransmitter inhibiting mechanism instead."
Skincare Empties: Unpopular Opinions, PEPTIDES, Why I Don't Use Green Tea with LED Therapy, & More!
"I did buy another bottle of The Ordinary Argireline. I really don't understand why anyone would use argireline anywhere other than the forehead, but I want to see if I can get more results from using a multipeptide serum all over my face with a little extra boost of argireline on my forehead."
"According to studies available and actual ingredient claims, this is an effective Peptide. It can't paralyze the muscle in the way Botox does. [...] The studies that we currently have on Argireline shows that this Peptide is very, very good at reducing the appearance of fine lines. [...] Whilst this is a great Peptide to decrease the depth of fine lines and wrinkles, this is not an ingredient to use if you're looking for longer term anti-aging effects or structural aging of your skin. [...] This is more on par with plumping, hydrating and moisturizing ingredients. In order to see results, you have to keep using this consistently forever. When you stop, results will stop too. Unlike other Peptides, some studies have shown that Argireline may be able to actually enter deeper into the skin, but it still can't reach deep down into the muscles to paralyze. That's maybe why The Ordinary themselves say it's good for fine lines around the eyes, because the skin around there is so thin. Current literature and current results don't show that this is really Botox in a bottle, but more an advanced Peptide, which is still amazing."
"This is the ordinary serum, the Argireline. I'm going to have to declutter this. This is definitely a fail for me. It irritates my skin even when my skin isn't normally irritated, so I'm definitely decluttering this. The Argireline is sort of that Botox in a bottle, but this formula either has too high a percentage. I find it drying and irritating, especially around my eye area. I'm definitely retiring the Argireline Solution."
"Argireline is said to work in a similar way to Botox. Obviously something that you put on your skin that is absorbed, even if it does get into that neuromuscular junction, probably won't work as well as Botox, and if you don't use it regularly it's not going to work. But if this is 10 or 15 dollars versus Botox at a couple of hundred, and if you're scared of needles and you don't want to do Botox, this is an option that doesn't make you do that. If it doesn't work, push comes to shove, you hydrated your face for 10 or 15 bucks, and if it does work, maybe you have a serum that's going to be a staple in your routine and helps you prevent wrinkles and fine lines in the long run. It's not Botox in a bottle, even though people claim it is. It's not the same as getting injections, but it is a really good option, especially if you're on a budget, and it's one of my top picks for fine lines and wrinkles specifically prevention."
All 3 takes from Cassandra Bankson
What Are 11 Lines and Can You Reverse Them At Home?!
"The Ordinary has one of my favorite argireline solutions. This actually works relatively well, a lot of people have had good results with it online, and even I've noticed that it hydrates my skin at the very least and maybe it is helping to temporarily slightly paralyze my glabellar complex muscles if I use it routinely. The results are going to vary for everyone, and although argireline is loved by many, some people say it doesn't work for them. [...] If it's something that looks promising and has science behind it but isn't medically proven with double blind placebo-controlled peer-reviewed studies, I'm not going to spend more than like 20 bucks on it, and that's why I love the Ordinary because this is inexpensive. This [...] goes on the skin and it is hypothesized to work similarly to a neuromodulator, essentially going on the skin and helping to temporarily paralyze the muscles. There's also hydrators in this formula that can help plump up the skin if you do have fine lines and wrinkles. Even putting on something like hyaluronic acid and ceramides or peptides can actually help to plump those outer layers of the skin so that maybe how this is working too. But at the end of the day, if you don't want to go for Botox, I think this is a decent option for the price."
3 Best The Ordinary Serums for Wrinkles (New and Existing!)
"Argireline is said to work in a similar way to Botox. Obviously something that you put on your skin that is absorbed, even if it does get into that neuromuscular junction, probably won't work as well as Botox, and if you don't use it regularly it's not going to work. But if this is 10 or 15 dollars versus Botox at a couple of hundred, and if you're scared of needles and you don't want to do Botox, this is an option that doesn't make you do that. If it doesn't work, push comes to shove, you hydrated your face for 10 or 15 bucks, and if it does work, maybe you have a serum that's going to be a staple in your routine and helps you prevent wrinkles and fine lines in the long run. It's not Botox in a bottle, even though people claim it is. It's not the same as getting injections, but it is a really good option, especially if you're on a budget, and it's one of my top picks for fine lines and wrinkles specifically prevention."
5 Best Serums From The Ordinary
"The Argireline Solution at 10 is one that I didn't always recommend, but as I've seen it do amazing things for people both online and in real life and in clinic, it's pretty impressive and for the price it's definitely worth a try. When it comes to all the peptides such as the Matrixyl, the copper peptides, everything the Ordinary offers, this one is a beautiful wrinkle mitigator, a graceful aging booster, and it's really easy to layer with moisturizers or other products, which is why I absolutely love it."
"Another good option here for peptides is acetyl hexapeptide-8, or Argireline as it's more commonly known. This one can work to mimic some of Botox's properties, certainly not to the same extent, and then it may have some benefits of its own. You can find it as a solo ingredient. There are some fairly affordable products with that, The Ordinary housing Argireline product."
What the evidence says.
Independent of what the gurus think, this is what
the published research supports about the main active ingredients here.
Peptides
Peptides are short protein fragments meant to signal repair. The evidence for them is thinner than for retinoids or vitamin C, and it varies a lot by the specific peptide, so the category is more promising than proven.
A lightweight serum containing 10% argireline (acetyl hexapeptide-8), a peptide designed to reduce the appearance of expression lines by limiting muscle contraction.
Is The Ordinary Argireline Solution 10% worth it?
The gurus are split. 12 of the 15 gurus give it their stamp of approval while 3 would skip it, which lands it in the middle at a Guru Score of 72%.
What is The Ordinary Argireline Solution 10%'s Guru Score?
The Ordinary Argireline Solution 10% holds a Guru Score of 72%. That is our read on how warmly the experts talk about it, based on the verdicts of 15 expert reviewers we have collected. At least one expert has named it a Top Pick in its category.
Who is The Ordinary Argireline Solution 10% best for?
The Ordinary Argireline Solution 10% is generally suited to mature skin.
Cheaper alternatives the gurus rate.
Lower-priced products in the same category that the experts still rate highly.