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Neutrogena Rapid Wrinkle Repair Retinol Pro+ Regenerating Cream.

Neutrogena Rapid Wrinkle Repair Retinol Pro+ Regenerating Cream
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Retinoids
About this product

A drugstore retinoid cream from Neutrogena, designed to target the look of wrinkles while moisturizing the skin.

Full ingredients

Water, Pentaerythrityl Tetraethylhexanoate, Glycerin, Dimethicone, PPG-15 Stearyl Ether, Stearyl Alcohol, Cetearyl Alcohol, Butylene Glycol, Glyceryl Behenate, Ceteareth-20, Isohexadecane, Dimethicone Crosspolymer, Cyclopentasiloxane, Cellulose, Sodium Polyacrylate, Phenoxyethanol, Caprylyl Glycol, Sodium Acryloyldimethyltaurate/​Vp Crosspolymer, Polyacrylamide, Fragrance, C13-14 Isoparaffin, Chlorphenesin, Polysorbate 20, Hydrolyzed Myrtus Communis Leaf Extract, Retinol, BHT, Sodium Hyaluronate, Disodium EDTA, Sodium Hydroxide, Laureth-7, Ascorbic Acid

More from Neutrogena 66 products · Guru Score 91% →

Guru Score

83%

Yay

14 experts · Strong agreement
#13 in RetinoidsSee the ranking →

What they liked

  • Affordable compared to luxury retinol products

What they flagged

  • May feel greasy or occlusive on application

What the gurus are saying

Its rich, dense texture keeps coming up, and gurus say it is better suited as a night cream for dry or sensitive skin. As an affordable first retinol it earns praise, but results may fall short of hopes for wrinkle or pore changes, so expectations need tempering. Starting with a couple nights a week gives skin time to adjust, and gurus caution against expecting overnight miracles.
Synthesized from 14 expert reviews · most recent take August 2026

Best for

Type

RetinoidsCream

Formula notes

Contains fragranceNo drying alcohol

Where to buy

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What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored
✓Yay
"It works by speeding up cell turnover and signaling your skin to produce more collagen. [...] Over the counter retinol is going to be gentler and slower than a prescription retinoid, [...] so I don't want you expecting overnight miracles, but as an affordable entry point it's a really good and reasonable place to begin. If you're new to it, start slow, maybe a couple nights a week, give your skin time to adjust, and always pair it with sunscreen in the morning."
All 2 takes from Dr. Aleksandra Brown
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"If you start over the counter there's Rock Neutrogena larage py they all have really good retinols"
The Best and Worst of Neutrogena: A Dermatologist's Honest Take
"It works by speeding up cell turnover and signaling your skin to produce more collagen. [...] Over the counter retinol is going to be gentler and slower than a prescription retinoid, [...] so I don't want you expecting overnight miracles, but as an affordable entry point it's a really good and reasonable place to begin. If you're new to it, start slow, maybe a couple nights a week, give your skin time to adjust, and always pair it with sunscreen in the morning."
✓Yay
"Neutrogena's Rapid Wrinkle Repair is one of the great gentle retinols you can get over the counter. [...] I think you can do very little harm to your skin by using a drugstore retinol like this."
All 6 takes from Dr. Jenny Liu
Dermatologist favorite drugstore retinol moisturizers | Dr. Jenny Liu
"The Neutrogena Rapid Wrinkle Repair is slightly a little more dense, a little harder to spread, and so for me that means the texture is just ever so slightly more nourishing. It's another great nourishing cream moisturizer that's going to be better suited for those with more dry and dehydrated skin, dry and sensitive skin to use at night."
Dermatologist creates anti-aging routine for $100 | Dr. Jenny Liu
"The pharmaceutical company that owns Neutrogena, in clinical studies, really upregulates retina receptors and response in the skin, improving the onset and benefits while reducing irritation. It also contains glycerin and dimethicone, which is why I think it gives the cream richness and creaminess and more support to your skin, especially if you have dry skin. I really love this one and recommend checking it out if you have dry skin and are looking for a good anti-aging retinal moisturizer."
Dermatologist Reviews Neutrogena's Retinol Cream and Pro Serum
"Comparing it to other retinol-based moisturizers, I think it's more on the creamier and richer side, but it's actually demonstrated in clinical studies to be very effective at targeting fine lines, skin texture, and skin tone. Johnson & Johnson conducted an eight-week double-blind study with 40 women who used this moisturizer once daily, and they noticed significant improvement in fine lines, wrinkles, skin texture, skin tone, and under-eye wrinkles."
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"Neutrogena's cream is very gentle, a really great one if you have extra drying sensitive skin. It's very nourishing and you can kind of put a moisturizer on top of that if you need."
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"If you're new to retinol and want something that's effective yet affordable, consider Neutrogena Rapid Wrinkle Repair. It's retinol plus hyaluronic acid, and hyaluronic acid is a wonderful ingredient [...] that helps to hydrate and plump the skin and support the skin barrier."
Your Skincare Routine Should Change Every Decade — A Derm Tells You Exactly How | Dr. Jenny Liu
"Neutrogena's Rapid Wrinkle Repair is one of the great gentle retinols you can get over the counter. [...] I think you can do very little harm to your skin by using a drugstore retinol like this."
✓Yay
"Neutrogena Rapid Wrinkle Repair, that one's very gentle. It's really great for sensitive skin."
All 2 takes from Dr. Mamina
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"The Neutrogena water bank is I think a pretty underrated moisturizer"
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"Neutrogena Rapid Wrinkle Repair, that one's very gentle. It's really great for sensitive skin."
✓Yay
"You can also try the Neutrogena Rapid Wrinkle Repair, which is available at a much lower price than the luxury retinol creams. When it comes to retinol, you do not need to pay luxury prices."
All 2 takes from 208SkinDoc
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"You can also try the Neutrogena Rapid Wrinkle Repair, which is available at a much lower price than the luxury retinol creams. When it comes to retinol, you do not need to pay luxury prices."
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"This is the Neutrogena Rapid Wrinkle Repair Retinol Pro Plus. This professional feeling retinol is a great addition to their lineup of products. It's going to cost a little bit more, and it really focuses on aging concerns of the skin. If you are more acne prone and wanting to use a retinol primarily for acne, I'd still go back and use the Differin we talked about earlier, but if your concern is more anti-aging, I think the Neutrogena is a really excellent option for you."
✓Yay
"I also love the new Neutrogena Rapid Wrinkle Repair Retinol Pro+ Regenerating Cream. This line though, I think there's the moisturizer, there's a serum. So whatever floats your boat, however you get in where you fit in with it."
✓Yay
"This one is a fond one for me. It's the first retinol product I ever used. Even though the concentration is not disclosed, [...] it is effective. They have a lot of studies backing it up. [...] This retinol is paired with a lot of hydrating ingredients, so it offsets irritation especially for someone who's just starting a retinol. I think this is a perfect pick."
All 2 takes from Doctorly
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"It was the first retinoid I ever used, the Neutrogena Rapid Wrinkle Repair. I'm sentimental in that way, but that's where I learned a lesson that my expectations need to be tempered. [...] I thought it would be a wrinkle eliminator, pore eliminator - these are things I hear, and that's what my expectation was. I was very disappointed even after perhaps using a full jar."
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"This one is a fond one for me. It's the first retinol product I ever used. Even though the concentration is not disclosed, [...] it is effective. They have a lot of studies backing it up. [...] This retinol is paired with a lot of hydrating ingredients, so it offsets irritation especially for someone who's just starting a retinol. I think this is a perfect pick."
✓Yay
"I would still recommend when you start any retinol product that you use it just a couple nights a week and slowly work it into your routine. Especially if someone is on a budget, new to using a topical retinoid, but wants to be doing a little bit more for their skin than just the basics of cleansing, moisturizing, and protecting from the sun, this one has my stamp of approval."
All 2 takes from Dr. Sam Ellis
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"I would still recommend when you start any retinol product that you use it just a couple nights a week and slowly work it into your routine. Especially if someone is on a budget, new to using a topical retinoid, but wants to be doing a little bit more for their skin than just the basics of cleansing, moisturizing, and protecting from the sun, this one has my stamp of approval."
Dermatologist Explains Retinols for Beginners with Affordable Drugstore Options! | Dr. Sam Ellis
"Another retinoid product from the drugstore that I love is the Neutrogena Rapid Wrinkle Repair Regenerating Cream. This is also quite a thick, rich cream. I find that it feels a little more occlusive than the Olay Regenerist, and for me that's a good thing."
✓Yay
"Neutrogena has made a nice regenerating cream. Their 1% is a rock, always one of my favorite over-the-counter retinols that you can consider. That was the first brand I used when I was a derm resident. You just use a pea-sized amount at bedtime."
All 12 takes from Dr. Daniel Sugai
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"There's the Neutrogena retinol [CeraVe] resurfacing Retinol Serum"
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"Another nice retinol to consider: Neutrogena's Rapid Wrinkle Repair. This has been around for a while. They came out with the new Retinol Pro+ where they actually disclose their percentages, which is nice. I've been liking that as well."
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"Neutrogena came out with a night cream that's 3% fragrance free in a jar. It's great stuff. Do a pea-size amount at bedtime and you can use it every other night to every night as tolerated. In the beginning, maybe start off just two or three times in the first couple weeks and then increase to nightly if you can. Do not use any retinol product if you are pregnant."
Dermatologist Reviews: Affordable Drugstore Skincare Essentials
"Neutrogena Rapid Wrinkle Repair Retinol Pro+ Regenerating Cream, I really like to pair this with the retinol oil, just feels so silky smooth afterwards. We love retinols because it will increase collagen production, especially if you use it for over 4 to 6 months consistently every night."
Dermatologist Explains: Anti-Aging Skincare Routine By Age
"You could also consider then increasing your retinoid. You can go for a higher percentage of retinol if it's over the counter like Neutrogena is starting to disclose their retinol."
Dermatologist Reviews Affordable Retinols: The Best Options For Your Skin!
"I like that Neutrogena has made a nice new retinol that will disclose the percentage. If you're in your 30s and up, go for Neutrogena either their regular OG Rapid Wrinkle Repair or if you want to go for their newer retinol Pro Plus, especially if you have tried their [...] original Rapid Wrinkle Repair and tolerated it, go for the higher one and see if you like it. I've actually enjoyed using that product. So just a shout out to Neutrogena for disclosing their percentage of retinol."
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"Neutrogena makes a nice one, the Rapid Wrinkle Repair. Over-the-counter options to start off with. I have been on a retinoid for over 10 years and I'm so glad I started in my mid-20s."
The Truth About Pore Size: Can You Really Shrink Them?
"Neutrogena has made a nice regenerating cream. Their 1% is a rock, always one of my favorite over-the-counter retinols that you can consider. That was the first brand I used when I was a derm resident. You just use a pea-sized amount at bedtime."
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"Neutrogena with a new retinol cream that's 0.3% I find to be quite nice so check that one out."
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"SV nutum number seven has made a nice retinol they have the 0.3% or the 1% retinol Neutrogena come out with serums oils and creams"
Dermatologist Explains: Which is the Best Retinol for You!
"Another great option that I've really enjoyed is Neutrogena's Rapid Wrinkle Repair Retinol. It could be fragrance or non-fragrance and very affordable. And they've even come with the Retinol Pro+ line that does disclose the retinol, whether it's a serum or the cream. So good job to Neutrogena for getting into the disclosure game and telling us what percent retinol you have in your products."
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"Neutrogena Olay and a ton of other retinols of various strengths that you can consider"
✓Yay
"Neutrogena Rapid Wrinkle Repair is a gentle retinol, it is safe for the neck, low chance of irritation. If you are choosing to treat signs of aging with a retinol which I think can be very beneficial but you have to be really careful, an example of a great gentle product would be Neutrogena Rapid Wrinkle Repair."
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"Neutrogena is one of the retinol options I love at the drugstore."
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"You should buy a Neutrogena retinol like the Rapid Wrinkle Repair product that has actual retinol in it"
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"Neutrogena Rapid Wrinkle Repair is a gentle retinol, it is safe for the neck, low chance of irritation. If you are choosing to treat signs of aging with a retinol which I think can be very beneficial but you have to be really careful, an example of a great gentle product would be Neutrogena Rapid Wrinkle Repair."
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"Two other absolute drugstore staples are the Neutrogena rapid wrinkle repair and the Olay retinol 24 max. I consider these similar products. These do not disclose their percentage strength of retinol, however many clinical studies show their efficacy. I like to use options like this on my neck and hands because I find them way more gentle in those sensitive skin areas."
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"My favorite drugstore retinoids for sensitive skin are Neutrogena Rapid Wrinkle Repair. I use this one actually on my neck and the tops of the hands. It's a combination retinol plus moisturizer product that really cuts down the potency and the irritation risk."
✓Yay
"The Neutrogena one is really good."
Translated from the guru's original language.
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"The Neutrogena one is really good."
Translated from the guru's original language.
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"Then you are going to start with like a basic like a Neutrogena and an Ole and something like that"
Translated from the guru's original language.
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"The Neutrogena retinol is 0.3% so if your skin is sensitive here, you can't start with that, whether it's oil or cream."
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"After the age of 25, get started on a gentle retinol based cream. Neutrogena retinol cream is 0.3%."
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"I highly recommend [...] Neutrogena as well. These are gentle, these are mild. Start by using a little bit of the product, which is a little more than a pea-size amount, and you can layer it. Use your niacinamide before that because these are cream forms."
✓Yay
"Just even a Neutrogena you could even do a Neutrogena like skin moisturizer anti-aging"
✓Yay
"The cosmetic retinoids I've been using the most are Neutrogena Retinol Pro Plus 0.3%."
✓Yay
"For those reasons, I feel like Neutrogena is definitely the best bet for retinol, and particularly this product because this product has 5% pure retinol. Even though it sounds like a small amount, it still is the clinically effective amount. [...] It costs about $45, but you're actually getting the real thing and you know how much is in there. This is a really nice lightweight serum, and it does have a couple of other ingredients to help it to stay stable in the bottle. It is fragranced."
All 3 takes from HotandFlashy
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"Neutrogena and its parent company Johnson & Johnson really is the company that did all the research into retinol 40 years ago and all the retinoids, so they're a really trusted brand."
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"For those reasons, I feel like Neutrogena is definitely the best bet for retinol, and particularly this product because this product has 5% pure retinol. Even though it sounds like a small amount, it still is the clinically effective amount. [...] It costs about $45, but you're actually getting the real thing and you know how much is in there. This is a really nice lightweight serum, and it does have a couple of other ingredients to help it to stay stable in the bottle. It is fragranced."
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"For a beginner retinol, I would recommend either Neutrogena Rapid Wrinkle Repair Cream or something like Olay Regenerist Retinol 24. [...] Of the two, I kind of prefer the Olay retinol line [...] over the Neutrogena, but they're both really good retinol products that you can get a good basic retinol at the drugstore."
✓Yay
"One of my holy grail favorite retinol products is the Neutrogena Rapid Wrinkle Repair Regenerating Retinol Cream. I've recommended that for years and I still do. [...] Not only do you get an excellent stable retinol, [...] but the moisturizing formula it's in gives you some immediate benefit too."
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"This is a retinol I have been recommending for years. Neutrogena as a brand has a long-standing track record of pretty intensive R&D as far as the retinol goes. That formula in particular, the base that it's in is so lux. I think it's more than adequate as a moisturizer. I don't think you really even need to be doing a moisture sandwich with that. It's so moisturizing."
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"One of my all-time favorite products from Neutrogena is their Rapid Wrinkle Repair regenerating retinol cream, fragrance-free with hyaluronic acid. This is an anti-wrinkle moisturizer with accelerated retinol, which means the retinol is fast-acting and goes to work efficiently. The SA stands for sustained action, a slow-release retinol so it allows for ongoing sustained action within your skin. It's an effective formula with highly stabilized retinol."
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"I highly praise it for an effective retinol formulation that does deliver results. Consistent use of this over a period of 2 to 3 weeks, you'll start to feel the retinol, and it may make you a touch sensitive. It's not necessarily to say that if you don't experience that it's not working, but it is reassuring that that appears at a predictable time point with these, and then your skin gets accustomed to it. This and the RoC, those are some retinols that you can feel confident in."
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"Retinol is a cosmetic ingredient that with consistent use can improve the visible signs of skin aging, improve the look of aging skin, can improve wrinkle depth. It can improve collagen production. I do suggest going with retinols from well-established brands that have a lot of R&D. And so those of you who have been here for a while, you know I always recommend the Neutrogena Rapid Wrinkle Repair Retinol."
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"The retinols that I've recommended in a lot of my videos from Neutrogena come in a jar package, but the formula is actually stable and the brands test the formula to be stable in that type of packaging system. [...] I learned firsthand when I toured the Dermatology warehouse and [...] saw all the testing that they put products through in terms of packaging to ensure stability."
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"When it comes to retinol specifically, I do encourage people to stick with brands that have large R&D. They have a large presence in the industry because they put a lot into their formulations. So I always recommend, for example, the Neutrogena Rapid Wrinkle Repair Retinol. Neutrogena has been doing retinols for a very long time, and they've taken their retinols into the clinic and done clinical studies on them."
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"Retinol is commonly found in wrinkle creams that you can buy in the drugstore. You don't have to spend a lot of money on these because some of the brands in the drugstore like Neutrogena [...] have a long-standing track record of intensive R&D behind these formulas. They tend to be a lot more reliable in comparison to just some random brand that popped up. [...] They've been as a brand working on retinol for a long, long time."
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"Even those sometimes can be intense, like the Neutrogena Rapid Wrinkle Repair Retinol Pro+ Regenerating Cream. Amazing. But I definitely got some flakiness and dryness with that on the neck once the retinol started kicking in because it's in a really great moisturizing base."
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"I've had good success using it on my neck, my upper chest as well without any irritation. Highly, highly recommend it if you are interested in trying retinol for cosmetic rejuvenation purposes."
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"This is one of my all-time favorites. It's great for mature skin, for improving the look of sun damage, like the chest, the arms, the legs. It's very hydrating. You can use it on the face, however if you're using a retinol to your face already or a prescription retinoid, I don't recommend double dipping."
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"I love Neutrogena retinols because Neutrogena, a Johnson and Johnson company, they've been doing retinols for a long time. They earned my trust long before I was ever on YouTube as an over-the-counter cosmetic retinol to recommend to patients, and you will see me recommend it over and over again. [...] Their retinols are some of the best in the industry in my opinion."
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"I like the Neutrogena Rapid Wrinkle Repair Retinol Pro+ Regenerating Cream. I've been recommending that for years."
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"Even those sometimes can be intense like the Neutrogena Rapid Wrinkle Repair Retinol Pro+ Regenerating Cream. I definitely got some flakiness and dryness with that on the neck once the retinol started kicking in because it's in a really great moisturizing base."
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"I like the cream though because it's very moisturizing and it has an instant wrinkle smoothing effect. Of course it takes time for the retinol to start working, but the pro plus retinol is another excellent option. The cream is also really luxurious, kind of a different consistency."
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"The Neutrogena Rapid Wrinkle Repair regenerating retinol cream is one I've been recommending for many years. It is an effective formula with sustained action slow release retinol. Neutrogena, you know the Johnson and Johnson company, has a long-standing track record of effective formulas for retinol tested on actual patients in the clinical setting. Definitely helpful for improving wrinkles."
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"One of my holy grail favorite retinol products is the Neutrogena Rapid Wrinkle Repair Regenerating Retinol Cream. I've recommended that for years and I still do. [...] Not only do you get an excellent stable retinol, [...] but the moisturizing formula it's in gives you some immediate benefit too."
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"Right now it's on sale for 26.99 for two jars, ordinarily 37.99, so that's an eleven dollar savings. Johnson and Johnson has put a lot of R&D behind their retinol formulations, and while we don't have a head to head trial comparing it to StriVectin, in my opinion this one is good and better, and it's more affordable, 26.99 versus the 78 dollars StriVectin was charging."
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"That's a really good one, the Neutrogena retinol cream. The base is very deeply hydrating and it really smooths everything out."
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"My favorite retinol cream is the Neutrogena Rapid Wrinkle Repair Regenerating Cream."
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"Neutrogena Rapid Wrinkle Repair is the retinol I'm always raving about, it uses a time release retinol so it's encapsulated for a slower release that minimizes irritation while still giving you maximum power."
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"This is one of my favorite retinol moisturizers, the Neutrogena Rapid Wrinkle Repair Regenerating Cream. Neutrogena has put so much work over the years into their retinols, you can really be confident that they are getting into the skin and helping with collagen production. They've been shown in clinical studies to actually work."
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"Seriously, this is honestly one of the best retinols in my opinion on the market. The cream itself, the vehicle that the retinol is in, is so moisturizing it almost has an instant skin plumping and hydrating and wrinkle smoothing effect just from the vehicle alone. Then with continued use the retinol can help in fading discoloration and improving the look of fine lines. Neutrogena has a large body of R&D behind their retinols so they're very trustworthy in that regard."
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"This is one by Neutrogena that I recommend. Retinol requires your skin [...] to convert it to its active form, which makes it less irritating but slower to work, but it can help improve wrinkles and fine lines."
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"This is probably one of my favorite retinol products and it is like my holy grail drugstore anti-aging product. Your skin has to convert retinol to the active form retinoic acid, which has to do two steps in order to get it there, but [...] the downstream effect with long-term consistent use is boosting up collagen production in the deeper layers of the skin to smooth out wrinkles and fine lines. It also helps improve the skin barrier."
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"The Rapid Wrinkle Repair Regenerating Cream is a product I hope they never ever discontinue. It almost gives the skin an immediate plumped look. [...] This product [...] has sodium hyaluronate that helps hydrate the skin and smooth out wrinkles and fine lines."
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"I always recommend the Neutrogena Rapid Wrinkle Repair [...] because it's from a large conglomerate that has a lot of R&D behind their products. More expensive doesn't necessarily mean better, but you don't need to spend a lot of money on retinols."
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"I have been recommending this for quite some time and I am a huge fan of their Rapid Wrinkle Repair Regenerating Cream. [...] Johnson & Johnson has been working on retinols for decades and they have the most patents on retinols with a long-standing track record of retinol formulation. It contains Retinol SA, which stands for sustained action, and it is a slow-release formulation that helps minimize irritation while allowing for effective delivery of the retinol."
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"I've always recommended the Neutrogena Rapid Wrinkle Repair Regenerating Cream. Their retinol is very, very good, but it is a thicker, heavier formulation. If you've got shiny skin, you may find that that kind of aggravates the sensations of heat and makes you look shinier. If you find that is an issue, then this might be too thick."
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"Their retinol is really good. It's been around for a long time and it's a good product. That looks good, although 35 dollars is kind of expensive."
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"This is a very good retinol, but that seems steep. [...] I don't know that I [...] would get a better deal at Walmart, but I haven't comparison shopped."

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Retinoids

Retinoids are among the best studied ingredients in dermatology, with solid evidence for acne and for the fine lines and rough texture that come from sun exposure. Dryness and flaking in the first few weeks are common and usually settle.

Source: DermNet

Vitamin C

Topical vitamin C is an antioxidant with reasonable evidence for dullness and uneven tone. It breaks down in light and air, so how a product is formulated and packaged matters as much as the percentage on the front.

Source: DermNet

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

Frequently asked.

What is Neutrogena Rapid Wrinkle Repair Retinol Pro+ Regenerating Cream?

A drugstore retinoid cream from Neutrogena, designed to target the look of wrinkles while moisturizing the skin.

Is Neutrogena Rapid Wrinkle Repair Retinol Pro+ Regenerating Cream worth it?

Yes. All 14 gurus who reviewed it give it their stamp of approval, for a Guru Score of 83%.

What is Neutrogena Rapid Wrinkle Repair Retinol Pro+ Regenerating Cream's Guru Score?

Neutrogena Rapid Wrinkle Repair Retinol Pro+ Regenerating Cream holds a Guru Score of 83%. That is our read on how warmly the experts talk about it, based on the verdicts of 14 expert reviewers we have collected.

Who is Neutrogena Rapid Wrinkle Repair Retinol Pro+ Regenerating Cream best for?

Neutrogena Rapid Wrinkle Repair Retinol Pro+ Regenerating Cream is generally suited to mature skin.

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