Murad

Targeted Wrinkle Corrector.

About this product

A targeted wrinkle corrector containing acetyl hexapeptide-8, designed to smooth fine lines and expression wrinkles.

Full ingredients

Water/Aqua/Eau, Polysilicone-11, Squalane, Propanediol, Cetyl Alcohol, Sodium Acrylates Crosspolymer-2, Potassium Cetyl Phosphate, Polyglyceryl-3 Laurate, Urea, Yeast Amino Acids, Trehalose, Inositol, Taurine, Betaine, Laureth-12, Chlorphenesin, Barium Sulfate, Sodium Acetylated Hyaluronate, Sodium Carbonate, Disodium EDTA, Glyceryl Oleate, Ethylhexylglycerin, Acetyl Hexapeptide-8, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol, Tocopherol

Guru Score

67%

Mixed

Early verdict · Few reviews so far

2Gurus

1Approved

0Mixed

1Skip

What the gurus are saying

Acetyl hexapeptide-8, this product's star ingredient, is marketed as Botox in a bottle, but dermatologists split on its real-world effectiveness. Some say it smooths expression lines. Others argue it likely works only through hydration, not by actually reaching the neuromuscular junction the way Botox does, and suggest trying The Ordinary's more affordable Argireline instead.

Synthesized from 2 expert reviews · most recent take August 2025

Best for

Mature skin

Key actives

Hyaluronic acidVitamin EPeptides Squalane

Formula notes

Fragrance-freeNo drying alcohol

Where to buy

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What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Approved takes Critical takes Mixed takes Hide sponsored

Dr. Shereene Idriss

1.72M subs

~Approved

"Murad has a Targeted Wrinkle Corrector and this is our gurene that relaxes expression lines."

Dr Dray

2.68M subs

~Skip

"Murad is charging 79 dollars for this and I don't think it's worth it, but it does have an ingredient people frequently ask me about, acetyl hexapeptide-8, otherwise known as Botox in a bottle or argireline. In theory it could act like botox, but there's no way it's actually getting down to the neuromuscular junction to relax and smooth out wrinkles like botox does. There is some research showing it does have a wrinkle smoothing effect, but that's likely just because it's a peptide, and peptides are hydrating, and hydrating ingredients smooth out fine lines by space filling. If you want to try this ingredient, go with The Ordinary's Argireline instead, you don't need this whole product, you could just use that underneath whatever moisturizer you're already using."

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Urea

Urea both holds water in the skin and gently loosens dead surface cells. At higher strengths it has good evidence for very dry or thickened skin.

Source: DermNet

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

Peptides

Peptides are short protein fragments meant to signal repair. The evidence for them is thinner than for retinoids or vitamin C, and it varies a lot by the specific peptide, so the category is more promising than proven.

Source: NIH, National Library of Medicine

Frequently asked.

What is Murad Targeted Wrinkle Corrector?

A targeted wrinkle corrector containing acetyl hexapeptide-8, designed to smooth fine lines and expression wrinkles.

Is Murad Targeted Wrinkle Corrector worth it?

The gurus mostly approve it, but with enough reservations to keep it in the middle at a Guru Score of 67%.

What is Murad Targeted Wrinkle Corrector's Guru Score?

Murad Targeted Wrinkle Corrector holds a Guru Score of 67%. That is our read on how warmly the experts talk about it, based on the verdicts of 2 expert reviewers we have collected.