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Medik8

Oxy-R Peptides.

Medik8 Oxy-R Peptides
Serums

About this product

A serum containing 1% oxyresveratrol and tetrapeptide 30, designed to brighten skin, fade hyperpigmentation, and boost radiance. Comes as two separate bottles to maintain antioxidant stability.

Type

Key actives

Formula notes

Fragrance-freeNo drying alcohol

Full ingredients

Guru Score

89%

Approved

Early verdict · Few reviews so far
2Gurus
2Approved
0Mixed
0Skip

What the gurus are saying

Oxyresveratrol and tetrapeptide work together to block tyrosinase, the enzyme that produces melanin, making this particularly effective for stubborn hyperpigmentation and melasma that does not respond well to other treatments. Gurus praise it as a gentler alternative to prescription options like hydroquinone, especially for those too sensitive for vitamin C. The dual-bottle design keeps the antioxidant fresh throughout use, since antioxidants break down quickly once exposed to air.
Synthesized from 2 expert reviews · most recent take July 2026
Every take, in full

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

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Approved
"This is the Medik8 Oxy-R Peptides. I love this. You get two vials that stay separated as powder and liquid to keep them fresh, you push it down, shake it, and the actives mix so you can use it. One vial lasts two weeks, so you get a month's supply. This is the best glow up hyperpigmentation fighting booster you will ever use. Once a year, usually for the whole month of August, I use this antioxidant powered brightening system to turbocharge my hyperpigmentation, and by the time September comes around it's breaking apart. You can use it year round, but I don't think I need to, it works so well I just use it for the month of August."
Top Pick: hyperpigmentation booster
All 3 takes from Mad About Skin
4x BETTER ANTI AGING (You Wont Believe The Results) - Medik8 Review
"This is a product I hear nobody speak about. It's just gone totally under the radar, but I think it's a true holy grail for certain people. What this does is it uses oxyresveratrol, which is a patented antioxidant known for being able to really brighten and lift the tonality of the skin, but it also is fantastic at fading hyperpigmentation, particularly stubborn hyperpigmentation. I gave it to my mom who has much more stubborn hyperpigmentation and melasma. She used both bottles and she absolutely loves it because it's helped lift the hyperpigmentation and the melasma in a way that a lot of things haven't. Melasma is particularly tricky to treat. You can reach for prescription things like hydroquinone but they come with a lot of side effects and you have to get the prescription. I would say this is like the next best thing when it comes to fading stubborn hyperpigmentation, lifting the skin, and just giving a really nice overall boost to radiance. It's also not super expensive."
10 Greatest ANTI AGING SERUMS - Skincare Awards 2025
"Instead of just giving you one big bottle which will then start to oxidize, they give you two. So, you can use them and activate them one at a time, keeping it super fresh. I love that. I love everything Medik8 do in the anti-aging game and this to me has been a little holy grail. Couple of drops of this morning and night and your glow game will be on point and you'll be radiating to the gods in no time. It genuinely works. If you're looking to boost radiance and luminosity, this is where it's at."
Official: WORLDS No1 SKINCARE BRAND - This Brand Transformed My Skin
"This is the Medik8 Oxy-R Peptides. I love this. You get two vials that stay separated as powder and liquid to keep them fresh, you push it down, shake it, and the actives mix so you can use it. One vial lasts two weeks, so you get a month's supply. This is the best glow up hyperpigmentation fighting booster you will ever use. Once a year, usually for the whole month of August, I use this antioxidant powered brightening system to turbocharge my hyperpigmentation, and by the time September comes around it's breaking apart. You can use it year round, but I don't think I need to, it works so well I just use it for the month of August."
Approved
"This product is genius. I feel like I haven't talked about it enough and it deserves more attention. So this has 1% oxyresveratrol which is a very potent yet gentle antioxidant that has all of the beneficial antioxidant effects but it also has the ability to inhibit tyrosinase which is an enzyme in our skin that produces melanin that produces pigment. So when you block that enzyme from functioning you reduce that excess pigment formation. In addition to the oxyresveratrol this also has tetrapeptide 30 which is a peptide that also blocks tyrosinase. So, specifically for people who have hyperpigmentation and especially for those who are too sensitive to use vitamin C, which is also great for hyperpigmentation, I highly, highly recommend you try this. I also feel like I should say since this bottle looks incredibly small, that one package of this comes with two bottles and you activate them separately so that you go through one entire bottle and then you activate the second bottle because the big issue with antioxidants is they can be quite unstable. Medik8 has done a very smart thing here and they have you go through half the product at once and then you can activate the other half of the product so that what you're using is always going to be in its most efficacious form."
Common questions

Frequently asked.

What is Medik8 Oxy-R Peptides?

A serum containing 1% oxyresveratrol and tetrapeptide 30, designed to brighten skin, fade hyperpigmentation, and boost radiance. Comes as two separate bottles to maintain antioxidant stability.

Is Medik8 Oxy-R Peptides worth it?

Yes. All 2 gurus who reviewed it give it their stamp of approval, for a Guru Score of 89%.

What is Medik8 Oxy-R Peptides's Guru Score?

Medik8 Oxy-R Peptides holds a Guru Score of 89%. That is our read on how warmly the experts talk about it, based on the verdicts of 2 independent expert reviewers we have collected. At least one expert has named it a Top Pick in its category.

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