Medik8 Crystal Retinal 20 is the highest-strength night serum in Medik8's Crystal Retinal range, made with retinaldehyde, a vitamin A derivative, to target fine lines, wrinkles and uneven texture.
Aqua (Water), Retinaldehyde, Caprylic/Capric Triglyceride, Cyclodextrin, Glycerin, Isododecane, Eclipta Prostrata Extract, Cetearyl Olivate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, PPG-12/Smdi Copolymer, Sorbitan Olivate, Tocopherol
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Guru Score
The Guru Score: every expert's verdict on a product, in one simple number.
Under the score you'll see how many experts weighed in, or "Early verdict" while only a few have. Paid takes count for half in the score.
Guru Certified means at least 6 experts, a score of 85% or more, and almost no Nays.
How we score →Yay
4 experts · Moderate agreementWhat the gurus are saying
Retinal 20 is the strongest retinaldehyde you can buy over the counter, the experts say. They found it works on fine lines and texture with far less irritation than tretinoin. The creamy formula doubles as a moisturiser, and the brand's record for keeping retinoids stable earns respect. It's potent, so start on a lower strength and work up. Sensitive skin should note the vanilla scent, and the packaging needs a squeeze to finish.
What they liked
What they flagged
Best for
Type
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Formula notes
The concerns the experts tie this product to, in their own words. Paid and founder takes don't count.
“For someone who maybe can't tolerate tretinoin or doesn't have access to tretinoin but is looking for something that is potent and is going to get the job done when it comes to helping with fine lines and wrinkles, textural problems, etc., this is my go-to.”
Dr. Sam Ellis, watch at 3:33
Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.
Independent of what the gurus think, this is what the published research supports about the main active ingredients here.
Retinoids are among the best studied ingredients in dermatology, with solid evidence for acne and for the fine lines and rough texture that come from sun exposure. Dryness and flaking in the first few weeks are common and usually settle.
Source: DermNet
Vitamin E is an antioxidant, and it is often in a formula to keep the other ingredients stable rather than as the active itself. It pairs well with vitamin C, though on its own the evidence for visible change is limited.
Medik8 Crystal Retinal 20 is the highest-strength night serum in Medik8's Crystal Retinal range, made with retinaldehyde, a vitamin A derivative, to target fine lines, wrinkles and uneven texture.
Yes. All 4 gurus who reviewed it give it their stamp of approval, for a Guru Score of 85%.
Medik8 Crystal Retinal 20 holds a Guru Score of 85%. That is our read on how warmly the experts talk about it, based on the verdicts of 4 expert reviewers we have collected.
Medik8 Crystal Retinal 20 is generally suited to mature skin.
In their reviews, experts say Medik8 Crystal Retinal 20 is good for fine lines and wrinkles (1 expert).
Lower-priced retinoids the gurus still rate highly, versus this mid-range pick.
See how they stack up →Other products the same gurus have weighed in on, plus more from this brand and category.
Compare side by side →Stories where our editors dug into this product or its brand.
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