Medicube

Medicube TXA 15% Plus Niacinamide Serum.

Serums

About this product

A hydrating serum with 10% niacinamide, 5% tranexamic acid, and 2% alpha arbutin, designed to brighten, soothe, and even skin tone.

Full ingredients

Water, Niacinamide(100,000Ppm), Glycerin, Butylene Glycol, Tranexamic Acid(50,000Ppm), Arbutin, Diethoxyethyl Succinate, Chlorphenesin, C12-14 Alketh-12, Ethylhexylglycerin, Xanthan Gum, Carbomer, Adenosine, Disodium EDTA, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, 1,2-Hexanediol, Panthenol, Cyanocobalamin, Betaine, Coccinia Indica Fruit Extract, Rosa Centifolia Flower Oil, Ferulic Acid, Corallina Officinalis Extract, Pentylene Glycol, Glutathione, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Dimethylsilanol Hyaluronate, Hyaluronic Acid, Potassium Hyaluronate, Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate Dimethylsilanol, Sodium Acetylated Hyaluronate, Acetyl Tetrapeptide-5, Hexapeptide-9, Palmitoyl Tripeptide-5

Guru Score

71%

Mixed

Early verdict · Few reviews so far

What they liked

Doesn't pill with other products
Watery, lightweight texture
Absorbs quickly

What they flagged

5% tranexamic acid may cause dryness or breakouts

What the gurus are saying

This serum earns strong praise for its thin, water-like texture that layers beautifully without pilling, making it a standout niacinamide formula. Gurus highlight its brightening power on dull skin and post-acne marks, and note it works well for combination and acne-prone skin, with no fragrance to irritate. However, the 5% tranexamic acid concentration has triggered dryness and breakouts in some people, so those with a compromised moisture barrier may want to patch-test first or start with fewer applications per week.

Synthesized from 2 expert reviews · most recent take August 2026

Best for

Dry skin Sensitive skin

Type

SerumsDrops & dropper

Key actives

Niacinamide Hyaluronic acid Peptides

Formula notes

Fragrance-freeNo drying alcohol

Where to buy

Ulta → Amazon → Google → iHerb →

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What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored

Sincerely Miss Ash

195k subs

~Yay

"This has 10% niacinamide, 5% tranexamic acid, and 2% alpha arbutin, all [...] tyrosinase inhibitors that help to brighten a dull complexion and fade post-acne marks and dark spots. It truly keeps your skin nice and even as much as possible even just using this on its own, and when I pair it with a vitamin C serum it truly takes my skin to the next level for brightness."

All 3 takes from Sincerely Miss Ash

5 KOREAN SKINCARE PRODUCTS I WISH I'D TRIED SOONER - K-BEAUTY MUST HAVES!

"This is exceptional, one of the nicest niacinamide serums I have ever used because it doesn't pill with my other skincare products. This has 10% niacinamide, 5% tranexamic acid, and 2% alpha arbutin, plus panthenol and 10 types of hyaluronic acid. It's a hydrating and soothing serum that also brightens. It's very thin like water, not sticky or tacky, and there's no fragrance. You can use it every day, twice a day, and pair it with vitamin C, tranexamic acid, retinol, or copper peptides."

8 SKINCARE PRODUCTS I CAN’T STOP USING RIGHT NOW | MY CURRENT FAVOURITES

"I'm actually almost done this product. I find it [...] to be very gentle, it has 10% niacinamide, 5% tranexamic acid, and 2% alpha arbutin, all of which help brighten the skin. It's great for [...] combo acne skin, [...] it's fragrance-free, it absorbs really nicely, and I love how quickly it works. This is 10 out of 10, perfect for summer but also all year round."

8 POWERFUL SKINCARE PAIRINGS THAT CAN ACTUALLY IMPROVE SIGNS OF AGING FASTER!

Nipun Kapur

412k subs

~Nay

"5% tranexamic acid is going to be very drying. Some people got breakout. One got breakout and one's skin became very dry. So her barrier was damaged."

Translated from the guru's original language.

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Niacinamide

Niacinamide has evidence behind it for redness, uneven tone and supporting the skin barrier, and it is usually well tolerated even by skin that reacts to most things.

Source: DermNet

Tranexamic acid

Tranexamic acid has a growing body of clinical evidence for melasma and the stubborn patches of pigment that other ingredients struggle with.

Source: DermNet

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

Frequently asked.

What is Medicube TXA 15% Plus Niacinamide Serum?

A hydrating serum with 10% niacinamide, 5% tranexamic acid, and 2% alpha arbutin, designed to brighten, soothe, and even skin tone.

Is Medicube TXA 15% Plus Niacinamide Serum worth it?

The gurus mostly approve it, but with enough reservations to keep it in the middle at a Guru Score of 71%.

What is Medicube TXA 15% Plus Niacinamide Serum's Guru Score?

Medicube TXA 15% Plus Niacinamide Serum holds a Guru Score of 71%. That is our read on how warmly the experts talk about it, based on the verdicts of 2 expert reviewers we have collected.