Medicube PDRN Pink Peptide Serum: a Guru Score of 68%

What the experts use it for.

The concerns the experts tie this product to, in their own words. Paid and founder takes don't count.

Loss of firmness3 experts

“This one has cell extracts in it for firmer, more elastic skin.”

Cassandra Bankson, watch at 19:50

Dark spots and post-acne marks1 expert

“They oddly claim that PDRN is going to help even out skin tone by removing dark spots.”

James Welsh, watch at 38:06

Skin barrier support1 expert

“And niacinamide has so many great benefits with skin barrier support, improving texture as well as brightening the skin.”

Dr. Jenny Liu, watch at 17:04

Dull skin1 expert

“It's really aimed at improving the quality of your skin, the appearance of fine lines, wrinkles, dullness, hydrating your skin, improving overall even tone.”

Dr. Jenny Liu, watch at 7:18

Rough or uneven texture1 expert

“And niacinamide has so many great benefits with skin barrier support, improving texture as well as brightening the skin.”

Dr. Jenny Liu, watch at 17:04

Fine lines and wrinkles1 expert

“It's really aimed at improving the quality of your skin, the appearance of fine lines, wrinkles, dullness, hydrating your skin, improving overall even tone.”

Dr. Jenny Liu, watch at 7:18

Skin recovering after a procedure1 expert

“It's one of the first things that I use after microneedling when I start adding skincare back into the mix.”

Darnell Cox | 50+ Healthy Aging Expert, watch at 4:29

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored

Darnell Cox | 50+ Healthy Aging Expert

55k subs

~Yay

"I went through two of these as well. [...] I love this. It's one of the first things that I use after microneedling when I start adding skincare back into the mix. Love, love, love this."

All 7 takes from Darnell Cox | 50+ Healthy Aging Expert

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"This is by Medicube. It's called PDRN Pink Peptide Serum that has changed my skin. I'm not kidding."

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"This is salmon sperm. This is a multi-peptide by Medicube. It's [...] PDRN Pink Peptide Serum. So it's got multiple peptides in it, but it also has nucleotides derived from salmon sperm. [...] The nucleotides in salmon sperm very closely match the nucleotides found in our skin. When we have genetic gaps, we're missing something, that's a sign of aging. [...] When your genes aren't replicating exactly how they're supposed to, that's a sign of aging."

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"I love a PDRN, this pink peptide by Medicube, the salmon sperm peptide. It works because the nucleotides of salmon sperm mimic the nucleotides in our skin, filling in genetic [...] gaps to make skin more resilient [...] and function better."

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"I like this PDRN by Medicube. This is part of the evening routine that I'm doing right now."

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"Let me give you an example, the Medicube PDRN serum. This is soothing and non-irritating, so it's one of the peptide products you can use right after micro needling without it stinging."

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"But then I will also, so here's my thing that I've been doing at night for the neck. I'll be doing the Medicube pink PDRN serum, the one skin first to uh handle those senescent cells um to get rid of those zombie cells, right? Clear the way. And that peptide is a great it's pink that is great for soothing of the neck."

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"I went through two of these as well. [...] I love this. It's one of the first things that I use after microneedling when I start adding skincare back into the mix. Love, love, love this."

James Welsh

1.58M subs

~Mixed

"Another nicely hydrating serum. They oddly claim that PDRN is going to help even out skin tone by removing dark spots. And I don't think that's what topical PDRN in any other cases even claim to do. I honestly think this won't be so popular if it wasn't pink."

Hyram

4.33M subs

~Nay

"That serum, I just can't get behind it because of the fragrance. But PDRN overall is definitely very beneficial."

All 2 takes from Hyram

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"That serum, I just can't get behind it because of the fragrance. But PDRN overall is definitely very beneficial."

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"This is an awesome one because it's an overnight serum that has AHA, BHA, and PHA at a 15% concentration."

Mad About Skin

734k subs

~Yay

"It's a gel formula too, so it's super lightweight, perfect for summer. [...] I love the fact that so many people are on board with it. I suspect it's a bestseller because people are using it alongside various devices. [...] You can do that, but honestly, I think in its own right it's great as a moisturizer. My top tip is to apply it fresh out of the shower, because it works best on damp skin. [...] Apply it liberally all over the body and you'll be set for the rest of the day."

All 7 takes from Mad About Skin

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"It's a gel formula too, so it's super lightweight, perfect for summer. [...] I love the fact that so many people are on board with it. I suspect it's a bestseller because people are using it alongside various devices. [...] You can do that, but honestly, I think in its own right it's great as a moisturizer. My top tip is to apply it fresh out of the shower, because it works best on damp skin. [...] Apply it liberally all over the body and you'll be set for the rest of the day."

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"I honestly think this is fantastic as a really nice affordable body care product. This is where it's at, and you get so much. [...] It's 300 mil, so you get a good amount of product. It's fragrance free and it's great for the body. [...] Of all the selections I'm talking about today, the one that's a run, don't walk moment when it comes to trying it is this one. It's such an amazing product, and I would recommend it to everyone looking to elevate their body anti-aging routine."

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"This is the Medicube PDRM booster gel. This is great to use with microcurrent because it stays slippy forever. So, it's great to use microcurrent and it's got PDRM, so it's anti-aging, too."

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"I love this. It's got peptides in too, so it really harnesses the anti-aging power of peptides alongside PDRN, for a double whammy. That to me is a 10 out of 10 when it comes to formulation. You get a lot of cream, and it's designed to be used as a gel alongside the Medicube devices they make to help create that slip on the skin. Sure, it works for that, but this is a great product in its own right. You don't have to have the devices to use it. You can just use this on its own."

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"It's phenomenal. I personally don't use it with devices, but I would say buy it, because if you're looking for something for dryness-prone skin with some anti-aging benefit, it doesn't get better than this. You get a lot of product. It's great for the body, and you can use it on the face too. It's just really, really good. [...] In winter, where I am here in the UK and it gets cold, [...] my skin is more dryness-prone, so I would probably put a moisturizer on top of this."

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"This is an absolute hit. I don't use it with any microcurrent device. I don't think that's necessary, but I use it all over the body. This is the nicest gel. It just is beautiful. And because you get so much of it, it's great anti-aging on the body. Just look how that goes in. It's cooling. It's soothing. It's hydrating. It is a real, real win. If you're wanting to get a dose of that PDRN for the body, I don't think you can go wrong with this. I [...] stand by it."

No BS Beauty

89k subs

~Nay

"This stuff smelled so strong, just floral perfumey. It was just too much. [...] The ingredients looked fine except for fragrance right in the middle and the fragrance was strong and it was overwhelming and it gave me the beginning of a migraine. So I didn't apply it on my face."

All 2 takes from No BS Beauty

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"This one has a small amount of sodium DNA, which is the PDRN that they mentioned. Sodium DNA is based from typically salmon. It contains DNA fragments, long chains of nucleotides that help support and repair and regenerate the skin. It also contains turmeric, ubiquinone, and five peptides, which are at the very end of the ingredient list. Aside from the fragrance, if it didn't have the fragrance in here, I'd probably be using it. [...] The strong scent is way way too much for my migraines."

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"This stuff smelled so strong, just floral perfumey. It was just too much. [...] The ingredients looked fine except for fragrance right in the middle and the fragrance was strong and it was overwhelming and it gave me the beginning of a migraine. So I didn't apply it on my face."

Dr. Jenny Liu

324k subs

~Yay

"It actually does contain salmon PDRN with a peptide complex and niacinamide to overall improve skin texture, tone, and help with skin rejuvenation. It's really aimed at improving the quality of your skin, the appearance of fine lines, wrinkles, dullness, hydrating your skin, improving overall even tone. It is hypoallergenic and suitable for sensitive skin."

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All 2 takes from Dr. Jenny Liu

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"It actually does contain salmon PDRN with a peptide complex and niacinamide to overall improve skin texture, tone, and help with skin rejuvenation. It's really aimed at improving the quality of your skin, the appearance of fine lines, wrinkles, dullness, hydrating your skin, improving overall even tone. It is hypoallergenic and suitable for sensitive skin."

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"It contains salmon sperm DNA peptide complex that works complimentary to the salmon sperm to enhance skin firmness and resilience. And niacinamide has so many great benefits with skin barrier support, improving texture as well as brightening the skin. So this one of all the ones that I've used is really one of my personal favorites."

Dr. Aleksandra Brown

153k subs

~Yay

"It's super lightweight hydrating serum. Helps improve even tone and boost elasticity for like that firmer, more radiant complexion. It absorbs pretty fast. I like to use it on top of my toner. It leaves you feeling really hydrated, plump. I do like moisturizer on top of it because I feel like it might be a little sticky otherwise, but I find a lot of serums sticky. [...] This one's great if you have dry skin, want hydration."

All 2 takes from Dr. Aleksandra Brown

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"The key ingredients is the salmon PDRN at 10,000 parts per million, five peptide complex, and holy basil leaf extract. [...] I find it to be just a little bit more hydrating. As a matter of fact, I have found it to be a little bit too hydrating to do videos like YouTube because I end up being too glowy. So, if you're somebody who's extra dry and you want like the best over-the-counter and you want to try PDRN, I would probably try the Medicube."

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"It's super lightweight hydrating serum. Helps improve even tone and boost elasticity for like that firmer, more radiant complexion. It absorbs pretty fast. I like to use it on top of my toner. It leaves you feeling really hydrated, plump. I do like moisturizer on top of it because I feel like it might be a little sticky otherwise, but I find a lot of serums sticky. [...] This one's great if you have dry skin, want hydration."

Nipun Kapur

413k subs

~Nay

"Just doesn't cut it for me. If you are in your 20, early 30s you can use it. Don't expect miracle it is just a nice hydrating product. But if you are oily acne prone this is not for you"

Translated from the guru's original language.

All 2 takes from Nipun Kapur

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"Medicube is something that can give you a lot of nourishment. It can give hydrate and moisturize your skin well. But if you're looking at the true magic of PDRN, and you will not know the magic of PDRN unless you have used a high quality product, Medicube is really a 5 on 10. From an anti-aging perspective, it is really a 5 on 10."

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"Just doesn't cut it for me. If you are in your 20, early 30s you can use it. Don't expect miracle it is just a nice hydrating product. But if you are oily acne prone this is not for you"

Translated from the guru's original language.

CYoung

96k subs

~Yay

"I tried the new disposable Medicube PDRN serum, it has a little scent but not too crazy, and a thick texture that kind of films on the skin. If you have oily combo skin it can feel kind of heavy, but if you use the massage device with it, it slides in really well and goes inside nicely. The PDRN amount is a lot higher compared to Anua, and it feels bouncy, which makes it great to use as a makeup primer."

All 3 takes from CYoung

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"I tried the new disposable Medicube PDRN serum, it has a little scent but not too crazy, and a thick texture that kind of films on the skin. If you have oily combo skin it can feel kind of heavy, but if you use the massage device with it, it slides in really well and goes inside nicely. The PDRN amount is a lot higher compared to Anua, and it feels bouncy, which makes it great to use as a makeup primer."

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"For me, this brand feels like a marketing company more than a cosmetic company, they make so many products and it's appealing on TikTok but maybe not in real life. But I'll admit this serum they made is okay, it has a lot more PDRN in it compared to the Anua PDRN serum, and even on my dry mature skin it felt pretty hydrating, they also do buy one get one promotions a lot at Olive Young. If you're curious about PDRN and want to try it, I'd say this isn't a bad choice, and it's cute too."

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"It contains PDRN at 10,000 PPM, which is 1 percent, a pretty high percentage, and also niacinamide, peptides, and coenzyme Q10, so it's really good as an antioxidant. It absorbs pretty quickly, but the texture isn't super light, and I like that. If you're dry, mature skin over 40, starting to get aging and your skin is getting thinner, you'll like it even more."

Gothamista

683k subs

~Yay

"I really love this new booster gel this is so elegant it's so refreshing it's not sticky at all"

AliceintheRabbitHole

59k subs

~Nay

"This just did not work for my skin type. I felt like I was getting an increase in redness when I used this product, though it's possible that came from the fragrance or the vitamin B12 ingredient rather than the PDRN itself, since this is a higher concentration than I'd knowingly tried up until this point. [...] So for me this is a no, I'm sure it will work for some amount of people, but it was sadly a no-go for me."

All 2 takes from AliceintheRabbitHole

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"This just did not work for my skin type. I felt like I was getting an increase in redness when I used this product, though it's possible that came from the fragrance or the vitamin B12 ingredient rather than the PDRN itself, since this is a higher concentration than I'd knowingly tried up until this point. [...] So for me this is a no, I'm sure it will work for some amount of people, but it was sadly a no-go for me."

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"I finally finished the Medicube HR Collagen Booster Gel. [...] I need this gel, you know I need it, so I made sure to get every last drop of it out of the packaging."

Kelly Driscoll

91k subs

~Nay

"And I just don't find this to be very compelling. I don't find it to be very worth it."

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Niacinamide

Niacinamide has evidence behind it for redness, uneven tone and supporting the skin barrier, and it is usually well tolerated even by skin that reacts to most things.

Source: DermNet

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

Peptides

Peptides are short protein fragments meant to signal repair. The evidence for them is thinner than for retinoids or vitamin C, and it varies a lot by the specific peptide, so the category is more promising than proven.

Source: NIH, National Library of Medicine

Frequently asked.

What is Medicube PDRN Pink Peptide Serum?

A gel-textured serum with salmon-derived PDRN, a five-peptide complex and niacinamide, designed to hydrate skin and improve its look and feel, including texture, tone and fine lines.

Is Medicube PDRN Pink Peptide Serum worth it?

The gurus are split. 7 of the 13 gurus give it their stamp of approval while 5 would skip it, which lands it in the middle at a Guru Score of 68%.

What is Medicube PDRN Pink Peptide Serum's Guru Score?

Medicube PDRN Pink Peptide Serum holds a Guru Score of 68%. That is our read on how warmly the experts talk about it, based on the verdicts of 13 expert reviewers we have collected. At least one expert has named it a Top Pick in its category.

Who is Medicube PDRN Pink Peptide Serum best for?

Medicube PDRN Pink Peptide Serum is generally suited to mature skin.

What is Medicube PDRN Pink Peptide Serum good for, according to the experts?

In their reviews, experts say Medicube PDRN Pink Peptide Serum is good for loss of firmness (3 experts), dark spots and post-acne marks (1 expert), skin barrier support (1 expert), dull skin (1 expert), rough or uneven texture (1 expert) and fine lines and wrinkles (1 expert).

Is Medicube PDRN Pink Peptide Serum good for loss of firmness?

3 experts who reviewed Medicube PDRN Pink Peptide Serum say it is. Cassandra Bankson put it this way: “This one has cell extracts in it for firmer, more elastic skin.”