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Mary&May

Spicule Retinol PDRN Cream.

Mary&May Spicule Retinol PDRN Cream
Retinoids

About this product

A Korean retinol cream combining nano liposome retinol with PDRN, centella asiatica, panthenol, shea butter and ceramides.

Guru Score

69%

Mixed

Early verdict · Few reviews so far
2Gurus
1Yay
0Mixed
1Nay

What they liked

  • A little goes a long way
  • Good introductory retinol before tretinoin
  • Moisturizer and retinol combined

What they flagged

  • Very strong smell

What the gurus are saying

This cream earns praise as a gentle introductory retinol that doubles as a moisturizer, with a texture where a little goes a long way. However, gurus note it has a very strong smell that may be off-putting. Those hesitant about prescription retinoids or looking to dip into retinol before moving to tretinoin may find this a good starting point, though you might want to patch-test first if you're sensitive to fragrance.
Synthesized from 2 expert reviews · most recent take August 2026

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

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~Yay
"One of my personal favorite retinol creams from Korea is the Mary & May Spicule Retinol PDRN Cream. If you're not familiar with Mary & May, they have awesome formulas, and all the ones I've tested from them I have really loved. This being the very first product I ever tried from Mary & May, it's a great one. It has nano liposome retinol, plus centella asiatica, PDRN, panthenol, shea butter and ceramides. A little bit goes a long way, but I feel like it's a great introductory retinol if you're a little bit nervous about trying US formulas, or especially before you veer into tretinoin or prescription retinoids. I'd definitely recommend an over the counter retinol product first, and this one is a great one for that if you want a two in one moisturizer and retinol in one."
~Nay
"Sadly, this one has a very strong smell."

Frequently asked.

What is Mary&May Spicule Retinol PDRN Cream?

A Korean retinol cream combining nano liposome retinol with PDRN, centella asiatica, panthenol, shea butter and ceramides.

Is Mary&May Spicule Retinol PDRN Cream worth it?

The gurus mostly approve it, but with enough reservations to keep it in the middle at a Guru Score of 69%.

What is Mary&May Spicule Retinol PDRN Cream's Guru Score?

Mary&May Spicule Retinol PDRN Cream holds a Guru Score of 69%. That is our read on how warmly the experts talk about it, based on the verdicts of 2 expert reviewers we have collected.

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