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SkinCeuticals

A.G.E. Interrupter Advanced Moisturizer.

SkinCeuticals
A.G.E. Interrupter Advanced Moisturizer
Moisturizers

About this product

A luxurious nighttime moisturizer formulated to target advanced glycation, containing proxylane and antioxidants to help restore collagen and support the skin barrier.

Guru Score

79%

Yay

4 experts · Moderate agreement
4Gurus
3Yay
1Mixed
0Nay

What the gurus are saying

This ultra-rich, balm-like cream targets advanced glycation to help clear out nonfunctional collagen and stimulate new collagen, a mechanism experts find particularly valuable for sensitive skin and anyone tackling sagging. The formulation includes 10% proxylane plus antioxidants and purple rice extracts, backed by clinical studies, though it's pricey. The ultra-rich texture won praise from most, though some found it off-putting along with the scent, so patch testing first is wise.
Synthesized from 4 expert reviews · most recent take July 2026

Type

Moisturizers

Where to buy

Opens a search for this product. We do not sell anything ourselves.

More from SkinCeuticals 15 products · Guru Score 81% → How it works Independent by design. Every take comes from a creator we have no relationship with. We do not ask anyone to review, and affiliate links never move a score.

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored
Dr. Jenny Liu
Dr. Jenny Liu
321k subs
✓Yay
"This video is not sponsored by SkinCeuticals, but in my practice I actually recommend their Advanced AGE Interrupter line, the serum and cream, for my GLP-1 patients as well as those who have sagging and want to complement skin tightening treatments, because studies have shown it helps augment the benefits of those procedures and inhibits the glycation process that's accelerated with GLP-1 medications. The serum has great ingredients like proxylane to combat glycation, and the advanced cream is very rich and helps to really improve the skin barrier."
All 6 takes from Dr. Jenny Liu
Best Splurge-Worthy products of 2023 from a Dermatologist | Dr. Jenny Liu
"This is probably one of my favorite moisturizers of 2023"
Black Friday 2024: Derm-Recommended Skincare & Haircare Deals You Can’t Miss! | Dr. Jenny Liu
"For anyone or even moms who are looking for a really rich great nighttime moisturizer that helps to tone and lift highly recommend checking out Skinceuticals Advanced AG Interrupter this is a really rich cream that I personally love"
Holiday Gift ideas from a dermatologist | Dr. Jenny Liu
"This is a rich luxurious moisturizer that you can certainly use twice a day but I really view it as a nice night cream and I feel like you can't go wrong gifting moms a night cream"
Holiday Gift Set Ideas | Dr Jenny Liu
"One of my probably hands-down my favorite moisturizer from skin ceuticals I love it even more than the triple lipid restore"
Ultimate Sensitive skincare guide for winter from Dermatologist | Dr. Jenny Liu
"The SkinCeuticals A.G.E. Advanced moisturizing cream is by far the most expensive moisturizer I'm recommending, but I've been obsessed and using it every night on my face and neck. It's a balm like, ultra rich, buttery texture that spreads nicely. The cream took about 15 years to formulate and targets advanced glycation, helping clear out nonfunctional collagen and elastin while stimulating new collagen. It has 10% proxylane plus antioxidants and purple rice derived extracts, the clinical studies are impressive, and it's a great one to splurge on especially for sensitive skin."
Ozempic Face Is Real | Dermatologist Explains How to Prevent & Fix It
"This video is not sponsored by SkinCeuticals, but in my practice I actually recommend their Advanced AGE Interrupter line, the serum and cream, for my GLP-1 patients as well as those who have sagging and want to complement skin tightening treatments, because studies have shown it helps augment the benefits of those procedures and inhibits the glycation process that's accelerated with GLP-1 medications. The serum has great ingredients like proxylane to combat glycation, and the advanced cream is very rich and helps to really improve the skin barrier."
Skin Obsessed Mary
Skin Obsessed Mary
33k subs
✓Yay
"Oh, it is so good."
Dr. Sam Ellis
Dr. Sam Ellis
882k subs
✓Mixed
"I will tell you just from personal experience, I have used this product and I just didn't enjoy it. Like, I didn't really like the texture of it. I didn't love the smell of it."
Nipun Kapur
Nipun Kapur
409k subs
✓Yay
"I would go ahead and use the Skin Ceuticals A.G.E. Interrupter Advanced"
All 2 takes from Nipun Kapur
My favorite skincare products for 2024 Mid Year review | Nipun Kapur
"Amazing results so I am continuing using this"
My top 5 anti aging skincare products | If I could use only 5 products for the rest of 2024
"I would go ahead and use the Skin Ceuticals A.G.E. Interrupter Advanced"

Frequently asked.

What is SkinCeuticals A.G.E. Interrupter Advanced Moisturizer?

A luxurious nighttime moisturizer formulated to target advanced glycation, containing proxylane and antioxidants to help restore collagen and support the skin barrier.

Is SkinCeuticals A.G.E. Interrupter Advanced Moisturizer worth it?

Mostly yes. 3 of the 4 gurus who reviewed it give it their stamp of approval, for a Guru Score of 79%.

What is SkinCeuticals A.G.E. Interrupter Advanced Moisturizer's Guru Score?

SkinCeuticals A.G.E. Interrupter Advanced Moisturizer holds a Guru Score of 79%. That is our read on how warmly the experts talk about it, based on the verdicts of 4 expert reviewers we have collected.

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SkinCeuticals A.G.E. Interrupter Advanced Moisturizer: a Guru Score of 79% from 4 experts on The Guru Index

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