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Skin1004 Probio-Cica Intensive Ampoule.

Skin1004 Probio-Cica Intensive Ampoule
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Mists & Essences
About this product

A lightweight hydrating ampoule serum with fermented centella asiatica, probiotics, niacinamide, and panthenol designed to soothe and strengthen the skin barrier.

Full ingredients

Centella Asiatica Extract, Butylene Glycol, Glycerin, Water, Propanediol, Caprylic/​Capric Triglyceride, Niacinamide, Lactobacillus/​Centella Asiatica Extract Ferment Filtrate, 1,2-Hexanediol, Dipropylene Glycol, Polyglyceryl-3 Distearate, Acrylates/​C10-30 Alkyl Acrylate Crosspolymer, C14-22 Alcohols, Arginine, Hydrogenated Lecithin, Betaine, Allantoin, Panthenol, Hydroxystearic Acid, Ethylhexylglycerin, Hydroxyethyl Acrylate/​Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Stearate Citrate, Sodium Polyacrylate, Adenosine, C12-20 Alkyl Glucoside, Cetearyl Alcohol, Xanthan Gum, Macadamia Ternifolia Seed Oil, Sodium Phytate, Sodium Hyaluronate, Stearic Acid, Ceramide, Glyceryl Acrylate/​Acrylic Acid Copolymer, Sorbitan Isostearate, Polyglyceryl-10 Myristate, Madecassic Acid, Asiaticoside, Phytosphingosine

More from Skin1004 33 products · Guru Score 90% →

Guru Score

84%

Yay

7 experts · Moderate agreement
#7 in Mists & EssencesSee the ranking →

What they liked

  • Hydrating and plumping without feeling greasy
  • Milky, lightweight gel texture absorbs easily
  • Soothing for irritated and sensitive skin

What they flagged

  • Needs a moisturizer on top for full hydration
  • Too much moisture for very oily skin

What the gurus are saying

This fermented centella ampoule earns consistent praise for delivering serious hydration in a lightweight, non-greasy texture that gurus say plumps and refreshes without feeling oily. The fermented centella, niacinamide, and probiotic complex work together to calm redness and support skin barrier health, making it especially valuable for anyone managing sensitive skin or using tretinoin. One note: apply it to damp skin and layer a moisturizer on top to lock in the hydration fully, since letting it dry alone leaves skin less moisturized than it could be.
Synthesized from 7 expert reviews · most recent take January 2026

Type

Mists & EssencesDrops & dropper

Key actives

Formula notes

Fragrance-freeNo drying alcohol

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What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

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✓Yay
"When I first tried it, I was a little more oily. I've even used it in very hot summer nights as the last step instead of a moisturizer. It has a lot of soothing ingredients, including panthenol as well as fermented ingredients. I really feel like it hydrates my skin well and helps calm it down. It features niacinamide. I actively look to have at least one niacinamide product in my routine because niacinamide helps tolerate Tretinoin and helps reduce the retinoid uglies."
✓Yay
"This is going to be great for folks with a balanced skin type, with a combination skin type, folks who are looking for some barrier care and strengthening in their serums as well as a skin healthy serum that can help to support a glowing complexion. This serum really focuses in on the benefits of Centella. Centella is a multi-beneficial ingredient. This is why you see it in so many skincare products because it can really do a lot for lots of different skin concerns."
All 6 takes from Kelly Driscoll
PM Routine w/ Tret | What Well-Aging Means to Me
"I've been liking this so much because it is all about your skin barrier and your microbiome. They're using fermented centella, there's ceramides and phytosphingosine in here, niacinamide, all kinds of good stuff for the health of your skin. I like that it is kind of like a creamy gel type of texture so it's got moisture to it but it's not like oily and rich, and so it's just perfect because I'm building up moisture but I'm building it up light on my skin."
Barrier Care for Cold Weather Skincare Routine
"This is the Skin1004 Probio-Cica Intensive Ampoule and I'm sticking with the same themes here right I want to get a little bit more of that probiotic goodness to really take care of my skin microbiome and make sure that I'm really giving my skin all of those beautiful nutrients the amino acids all of that goodness that really helps to keep our skin healthy and really helps it glow with that health."
A Tale of 2 Ceramides | Torriden Solid-In + SKIN1004 Probio-Cica Lines
"This really does hydrate the skin and it plumps it up, dives a little deep, feels really refreshing. [...] As it is settling and absorbing into the skin you're going to feel that kiss of moisture, it doesn't feel greasy, it doesn't feel oily, but it's just that right amount that just gently hugs everything in. You can easily add on other skincare products on top of this without overwhelming your skin."
The Best Skincare of 2023! 🎉
"I'm not sure if this product came out exactly in 2023 but it really starts to gain popularity in 2023. Not only was I impressed with the product and the performance for me personally but in the greater K Beauty world I felt like this was a really smart release that expanded the line of Skin1004. What I found really impressive is that it really takes Skin1004 into a different realm."
My SKIN1004 Top 5 Picks!
"It's really one of my favorite offerings from them. [...] They really have built their name and their success on [Centella], and they do have a lot of different [Centella] offerings, but for me particularly, I love the Probio-Cica line because it really does step up the [Centella]. It really brings up the quality, brings up the intensity, brings up the benefits of [Centella]. In the Probio-Cica line and specifically in the ampoule, they are using fermented [Centella]."
Nourishing Serums for Fall! 🍁
"This is going to be great for folks with a balanced skin type, with a combination skin type, folks who are looking for some barrier care and strengthening in their serums as well as a skin healthy serum that can help to support a glowing complexion. This serum really focuses in on the benefits of Centella. Centella is a multi-beneficial ingredient. This is why you see it in so many skincare products because it can really do a lot for lots of different skin concerns."
✓Yay
"Anything skin1004 touch turns to gold in my view they haven't got a bad product all of them are amazing and the probiose line is so so good"
All 2 takes from Mad About Skin
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"I like Skin1004 in general as a brand. I really like them. I think they've got a really good set of ethics behind them. I think they're well formulated. I like their packaging is really really nice. My only critique of them would be I think they do have maybe too many products that are very similar. Everything has Cica in it. You can't really overdo Cica too much, but there is a risk potentially you could if you're not careful. So there is a little bit of I think maybe they do overdo it."
SKINCARE LIVESTREAM - Skincare Chat, Giveaways, Skincare Gossip and more
"Anything skin1004 touch turns to gold in my view they haven't got a bad product all of them are amazing and the probiose line is so so good"
✓Yay
"This is their newest collection, the Probio-Cica line, and I love it. It's an intensive ampoule with fermented cica ingredients like panthenol, which is great for nourishing and caring for your moisture barrier, plus the active parts of cica like madecassoside and asiatic acid, all making a product that is very hydrating, moisturizing, and great for sensitive skin. It makes sense they made this a milky serum, [...] and you really do [...] see soothing benefits from it."
✓Yay
"The Skin1004 Probio-Cica Intensive Ampoule has a very simple ingredient list, nothing super fancy. It has a fermented filtrate from [Centella] and that imparts humectants, anti-inflammatory compounds. [...] It does very similar things [...] as far as just imparting that overall plump, firm, smooth, suppleness to the skin surface, brightening up skin tone. And it's not really an over-the-top complex formula. I've repurchased this before. It takes a long time to go through this too."
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All 13 takes from Dr Dray
Relaxing Day Doing My Skincare And Makeup Routine
"I came in with the Madagascar [centella] Pro bioa serum this is super hydrating and it kind of enveloped vs the skin in a nice little hug to reduce water loss"
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"I love it, love it, love it. This is like bottle number three or four for me. I also love the corresponding cream. [...] You do want [...] to layer your moisturizer on over it because if you let it dry down, you're going to have less than moisturized skin. It's just not the full shebang. This can give you the full shebang. You can layer more moisturizer on over it if you want."
Mixsoon Bean Essence Vs Cosrx Snail Mucin
"The Skin1004 Probio-Cica Intensive Ampoule has been a 10 out of 10 for me. It's very hydrating and contains a lactobacillus centella ferment which contains hydrating and anti-inflammatory compounds. This also has niacinamide which is good for redness, hyperpigmentation, dry skin, and may help in reducing oxidative stress. It can be used one to two times a day applied to the face after cleansing and can also be used alongside other skincare ingredients provided you tolerate the combination."
*MUST TRY* Korean Skincare For Healing The Skin Barrier
"A couple of years ago I discovered from one of my favorite Korean brands Skin1004 their Probio-Cica line and let me tell you I have been so impressed with their ampoule. Very minimal ingredient list, which is nice to have a really simple formula especially when you may be very sensitive trying to keep your routine very minimal. [...] The Probio-Cica Intensive Ampoule has lactobacillus, centella asiatica extract ferment filtrate."
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"The Probio-Cica Ampoule has been a 10 out of 10 for me. It's very hydrating. It contains a lacto-C Cica ferment which contains hydrating and anti-inflammatory compounds. This also has niacinamide which is good for redness, hyperpigmentation, dry skin, and may help in reducing oxidative stress. This can be used one to two times a day applied to the face after cleansing. Can also be used alongside other skincare ingredients provided you tolerate the combination."
Skincare Shopping & Tips For Breakouts *Vlog*
"I actually put it on over the Madagascar [centella] Pro bio seea serum so I'm like super moisturized and hydrated"
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"I came in with the Skin1004 Probio-Cica Intensive Ampoule. Look at how much I have made my way through on this bad boy. I love this stuff. It's really good. Very hydrating, moisturizing, and soothing."
So Many Empties 🗑 Skincare And Hair Care I Used Up 2023
"This has become a 2023 Korean skin care favorite. [...] It's the Skin1004 Madagascar Centella Probio-Cica Intensive Ampoule. This has a lactobacillus centella ferment. Fermentation refers to basically chemical reactions performed by microorganisms, and [...] fermentation is utilized in skincare and in some cases it may actually enrich for more active ingredients, get them in a more bioavailable form. [...] I really found it to be a very hydrating and pleasurable ampoule to use."
Scalp Care & What's In My Closet
"This is a product from Skin1004, the Madagascar Centella Probio-Cica Intensive Ampoule, and the ferment in this I think is what takes it above and beyond the centella ampoule. It has a creamier milkier slippery texture and you guys know I'm a big fan of that slip and slide and glide. [...] I love the slippery slimies, the ferments, all that juicy juicy juicy goodness."
SEPTEMBER 2023 SKINCARE FAVORITES
"But the Intensive Ampoule, wow, I was not expecting to like this as much as I did. [...] It's got centella in it, it has niacinamide. Niacinamide is anti-inflammatory, it's good for hyperpigmentation, redness, the moisture barrier, skin yellowing. It has a lot of benefits to the skin provided you tolerate it. [...] This product has lactobacillus and centella ferment, and I think that's the magic ingredient across this whole line. [...] The consistency of this takes it to another level."
Must Try Korean Skincare For Summer
"It has polyglutamic acid, which is great for hydrating and improving skin elasticity. And [...] one of the reasons I love this so much is that I find when I use this, similar to when I use snail mucin, I get an improvement in that snap, that recoil that is characteristic of better elasticity. And I feel like the skin to the touch is firmer, plumper, dewier. It's fragrance-free."
Dermatologist Skincare Empties: What I’d Actually Buy Again
"The Skin1004 Probio-Cica Intensive Ampoule has a very simple ingredient list, nothing super fancy. It has a fermented filtrate from [Centella] and that imparts humectants, anti-inflammatory compounds. [...] It does very similar things [...] as far as just imparting that overall plump, firm, smooth, suppleness to the skin surface, brightening up skin tone. And it's not really an over-the-top complex formula. I've repurchased this before. It takes a long time to go through this too."
Best Korean Skincare Products Of The Year
"It is so hydrating. Again, very pleasurable to use. I really enjoyed the slippery smooth texture. It's a lot like using snail mucin, not quite as stringy slimy, but it's got that slime appeal which I actually really like. It's hydrating. It has ceramide in it, which is good for skin's moisture barrier. It has panthenol, which also is good for dry skin. Allantoin is anti-inflammatory. The main sort of featured ingredient is the lactobacillus centella extract ferment."
✓Yay
"My skin is more on the oily side so I find that this works really well as a moisturizer instead of moisturizer. This is a really nice soothing product for when my skin is irritated. It's a nice supportive product even though it does have this sort of gooey texture after you put it on your skin, or on my skin at least it sinks in really nicely. It doesn't feel like sticky or anything. It's just very lightweight and very hydrating."
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✓Yay
"Skin1004 Probio-Cica Intensive Ampoule, another one that's on the rise I feel, packed with probiotics for health your skin. They have their probiotic complex in here which helps strengthen the skin barrier and promotes a balanced microbiome, which I don't know a lot about, I need to get to know more about it, but I know it's important for your skin and is actually something I feel like has potentially really really helped with my rosacea."
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What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Niacinamide

Niacinamide has evidence behind it for redness, uneven tone and supporting the skin barrier, and it is usually well tolerated even by skin that reacts to most things.

Source: DermNet

Ceramides

Ceramides are part of the skin's own barrier, and moisturisers built around them have evidence for holding water in and settling the tightness and flaking that come with a damaged barrier.

Source: DermNet

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

Frequently asked.

What is Skin1004 Probio-Cica Intensive Ampoule?

A lightweight hydrating ampoule serum with fermented centella asiatica, probiotics, niacinamide, and panthenol designed to soothe and strengthen the skin barrier.

Is Skin1004 Probio-Cica Intensive Ampoule worth it?

Yes. All 7 gurus who reviewed it give it their stamp of approval, for a Guru Score of 84%.

What is Skin1004 Probio-Cica Intensive Ampoule's Guru Score?

Skin1004 Probio-Cica Intensive Ampoule holds a Guru Score of 84%. That is our read on how warmly the experts talk about it, based on the verdicts of 7 expert reviewers we have collected.

Who is Skin1004 Probio-Cica Intensive Ampoule best for?

Skin1004 Probio-Cica Intensive Ampoule is generally suited to dry skin and sensitive skin.

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