Sederma

Sederma Volufiline.

Save to Pinterest

About this product

A skincare treatment containing Volufiline, an active ingredient marketed to plump skin and enhance facial volume by stimulating fat cell development.

Guru Score

61%

Mixed

Early verdict · Few reviews so far

What the gurus are saying

This ingredient sounds too good to be true, and dermatologists are skeptical it delivers what's promised. Even if Volufiline could reach deep enough into the skin to affect fat cells, the practical result would be so subtle you might not see it without professional imaging tools, and the safety questions around stimulating fat growth raise concerns. At most, any visible benefit likely comes from basic skin hydration, which you can get from a standard moisturizer.

Synthesized from 2 expert reviews · most recent take February 2026

Best for

Mature skin

Type

Liquid

Where to buy

Amazon → Google →

Opens a store search. We may earn from these links.

Scan it in the shopFree iPhone app. Scores in the aisle.

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored

Dr. Jenny Liu

323k subs

~Mixed

"At the end of the day, this is way more hype than science. [...] At best, you're going to get some superficial plumping of your skin, helping your skin just look healthier, maybe glowier. But even if it does improve the fat in your face, that is going to be so subtle that you may not even notice it visually, that may be something you could measure with an instrument that we would use like Visia in office when we conduct clinical studies."

Dr Dray

2.69M subs

~Nay

"What do I think of this ingredient? I think it sounds too good to be true, it likely is. I've never used it, but honestly I would say the same exact thing even if I used it. I'm skeptical that this is doing anything to stimulate adipocyte differentiation in the face. You're applying it to the surface of the skin, how is that compound actually going to penetrate all the way into the skin, across the dermis, into the subcutaneous where the fat is, to influence fat cell differentiation?"

Frequently asked.

What is Sederma Volufiline?

A skincare treatment containing Volufiline, an active ingredient marketed to plump skin and enhance facial volume by stimulating fat cell development.

Is Sederma Volufiline worth it?

The gurus mostly approve it, but with enough reservations to keep it in the middle at a Guru Score of 61%.

What is Sederma Volufiline's Guru Score?

Sederma Volufiline holds a Guru Score of 61%. That is our read on how warmly the experts talk about it, based on the verdicts of 2 expert reviewers we have collected.