Volufiline.

"At the end of the day, this is way more hype than science. [...] At best, you're going to get some superficial plumping of your skin, helping your skin just look healthier, maybe glowier. But even if it does improve the fat in your face, that is going to be so subtle that you may not even notice it visually, that may be something you could measure with an instrument that we would use like Visia in office when we conduct clinical studies. [...] You're definitely not going to get the effect of a filler in a bottle."

"What do I think of this ingredient? I think it sounds too good to be true, it likely is. I've never used it, but honestly I would say the same exact thing even if I used it. I'm skeptical that this is doing anything to stimulate adipocyte differentiation in the face. You're applying it to the surface of the skin, how is that compound actually going to penetrate all the way into the skin, across the dermis, into the subcutaneous where the fat is, to influence fat cell differentiation? Even if it did work the way they claim, that seems questionable in terms of safety, you could end up with lipomas, fatty tumors. I really just don't think that this does what it claims it does. At the most I do think you will see an improvement in skin hydration with this ingredient, that seems plausible, but a lot of that could just be achieved by using a basic moisturizer. I certainly do not recommend applying the raw material directly to your skin, that can be incredibly irritating."