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Prequel

Universal Skin Solution Dermal Spray for Face and Body.

Prequel Universal Skin Solution Dermal Spray for Face and Body

About this product

A hypochlorous acid spray for face and body designed to soothe irritation, reduce redness, and support skin barrier function.

Best for

Sensitive skinAcne-prone skin

The Guru Index verdict

82%

Approved

Approved · 82%
5Reviewers
5Approved
0Mixed
0Skip

What the gurus are saying

Gurus across the board praise this spray for calming redness, irritation, breakouts, and rosacea flare-ups, plus its versatility for body use and post-procedure prep. The fine mist application and affordable price consistently stand out. The main caveat is that hypochlorous acid can deactivate antioxidants like vitamin C, so users need to time application carefully or use it in the evening. Some note it's not available outside North America.
Synthesized from 5 expert reviews

Key actives & flags

Fragrance-freeAlcohol-free

Full ingredients

Water (Aqua)*, Hypochlorous Acid, Sodium Chloride, Sodium Phosphate, Disodium Phosphate

Every take, in full

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Approved only Skip only Mixed only Hide sponsored
Approved
"I use the one by Prequel. This is called the Universal Skin Solution Dermal Spray. This is a really great formulation at a great pH and a super affordable price, even better than many of the other popular ones out there. I just do a quick spritz over the surface of the skin. Hypochlorous acid is not just a great treatment for acne because it's antimicrobial and can kill that acne-causing bacteria, but it also reduces inflammation on your skin and can help rebuild the microbiome of your skin and strengthen your skin barrier, which are all very important things when you are putting a retinoid, which is irritating, on the skin."
Approved
"I'm going to go in with the Prequel Universal Skin Solution Dermal Spray. This is hypochlorous acid. This is, I guess, kind of to rewet it. This isn't really a toner but you guys have heard me talk about how much I love this stuff. It's great for any redness. For me, I was dealing with my perioral dermatitis under here, which you can see is getting better. I like to let that dry down just because it can deactivate some of your other skincare products."
All 2 takes from Mixed Makeup
My Updated Skincare Routine for Melasma & Dark Spots
"This is from Prequel, this is the Universal Skin Solution Dermal Spray. This is just a hypochlorous acid spray, and there's a reason for it, it is great for anybody who has skin irritation. For me with peroral dermatitis, and because of my melasma, I have noticed that anytime I get really red, like if I'm irritated, I have redness, or if I spent too much time at the gym, or if I was out in the sun, if I got really hot, I will keep a bottle of this. I also like spraying it on my back so I don't get breakouts. If you're going to use any antioxidants like retinoids or AHA, then you want to let it dry down before you go in with some of your other products. It's essentially like spraying bleach on your skin, so just keep that in mind. But I think this is just such a great type of product to have in your routine and in your bag, and it's like a catchall for so many different skin issues. If you're dealing with any redness like I do, that redness can lead to more melasma."
Nighttime Skincare Routine for Perioral Dermatitis & Melasma
"I'm going to go in with the Prequel Universal Skin Solution Dermal Spray. This is hypochlorous acid. This is, I guess, kind of to rewet it. This isn't really a toner but you guys have heard me talk about how much I love this stuff. It's great for any redness. For me, I was dealing with my perioral dermatitis under here, which you can see is getting better. I like to let that dry down just because it can deactivate some of your other skincare products."
Approved
"My new favorite is Prequel's Universal Skin Solution Dermal Spray. Hypochlorous acid, I always say it's like an anti-bacterial for your face. It helps with skin irritation, redness, breakouts, cuts, grazes. If you picked a spot, it's going to help soothe it. This has been my everything for everything. When my rosacea is flaring up, spray on, soothes it. Breakouts, irritated skin, I get really irritated like on my sideburns for some reason. Knowing I have sprays like this, soothing serums, skin barrier repairing moisturizers that are going to help soothe it quicker, I worry about it a lot less. This has hypochlorous acid, sodium chloride, sodium phosphate, disodium phosphate, and electrolyte water. I found this while I was doing my doggy first aid course and they're selling this as antiseptic skincare. It's hypochlorous acid. What I will say though is this isn't available in the UK, it's not available in Europe."
All 2 takes from James Welsh
Are Dermatologist Skincare Brands Actually Any Good? 🤔 Remedy, Dr Idriss, Prequel
"Hypochlorous acid is something that Dr Sam Ellis says that she uses on her clients before services like Botox, filler, micro needling. There's also soothing mineral concentrate in here which they say is an optimal magnesium content to help soothe and strengthen the barrier function of the skin. I use this every single day without fail because I've always got rosacea, I'm kind of always breaking out, and it does just calm everything down. It's great for cuts and scrapes, you could use it on your pets if they've got a little cut. There is a little bit of talk how hypochlorous acid can basically render your antioxidants useless, so I personally use this in the evening. I have started using a vitamin C more in the mornings just for its antioxidant benefits, so I would use hypochlorous acid in the evening when I'm not using vitamin C and let that dry down completely before I go into my next steps."
This Is My Best Skincare Routine So Far - Top 10 Favourite Skincare Products
"My new favorite is Prequel's Universal Skin Solution Dermal Spray. Hypochlorous acid, I always say it's like an anti-bacterial for your face. It helps with skin irritation, redness, breakouts, cuts, grazes. If you picked a spot, it's going to help soothe it. This has been my everything for everything. When my rosacea is flaring up, spray on, soothes it. Breakouts, irritated skin, I get really irritated like on my sideburns for some reason. Knowing I have sprays like this, soothing serums, skin barrier repairing moisturizers that are going to help soothe it quicker, I worry about it a lot less. This has hypochlorous acid, sodium chloride, sodium phosphate, disodium phosphate, and electrolyte water. I found this while I was doing my doggy first aid course and they're selling this as antiseptic skincare. It's hypochlorous acid. What I will say though is this isn't available in the UK, it's not available in Europe."
Approved
"I have the Prequel Universal Skin Solution Dermal Spray for Face and Body, which is another great option. I have atopic dermatitis that gets aggravated by my sweat, and that makes me really itchy. I find hypochlorous acid sprays really beneficial, mostly for my body. I don't really use them too often on my face, from time to time I do, but primarily on my body."
All 2 takes from Dr Dray
Is Prequel Skincare Worth It?
"It is a good product if you're on the hunt for a hypochlorous acid spray and I don't really think it's that expensive in general."
Skin Benefits Of Hypochlorous Acid
"I have the Prequel Universal Skin Solution Dermal Spray for Face and Body, which is another great option. I have atopic dermatitis that gets aggravated by my sweat, and that makes me really itchy. I find hypochlorous acid sprays really beneficial, mostly for my body. I don't really use them too often on my face, from time to time I do, but primarily on my body."
Approved
"This is the Prequel Universal Skin Solution, it is hypochlorous acid. It's a very gentle refresher for the skin, it's antimicrobial, it's anti-inflammatory, and it's what I use every day in my own clinic to prepare my patient skin for procedures. It helps cleanse the skin. I found that sometimes people who have very sensitive skin have low-grade irritation going on from their environment or they have an unusual microbiome, so the bacteria and fungi and viruses that sit on their skin sensitize it, and using something like hypochlorous acid in your routine can be so helpful. I love this one in particular because the mist is just so beautifully fine. I often will use this after I work out, but it's also so gorgeous in a nighttime skincare routine and it's so refreshing. We launched this product over a year ago now, and since then so many of my patients have come in and said that this truly saved their skin, whether they were dealing with perioral dermatitis or a little eczema patch. People put this on bug bites and just random rashes."
SponsoredFounder Conflict
All 8 takes from Dr. Sam Ellis
My Sensitive Skin Nighttime Skincare Routine as a Dermatologist | Dr. Sam Ellis
"This is the Prequel Universal Skin Solution, it is hypochlorous acid. It's a very gentle refresher for the skin, it's antimicrobial, it's anti-inflammatory, and it's what I use every day in my own clinic to prepare my patient skin for procedures. It helps cleanse the skin. I found that sometimes people who have very sensitive skin have low-grade irritation going on from their environment or they have an unusual microbiome, so the bacteria and fungi and viruses that sit on their skin sensitize it, and using something like hypochlorous acid in your routine can be so helpful. I love this one in particular because the mist is just so beautifully fine. I often will use this after I work out, but it's also so gorgeous in a nighttime skincare routine and it's so refreshing. We launched this product over a year ago now, and since then so many of my patients have come in and said that this truly saved their skin, whether they were dealing with perioral dermatitis or a little eczema patch. People put this on bug bites and just random rashes."
Dermatologist Explains Hypochlorous Acid: How to Use it in Your Skincare Routine | Dr. Sam Ellis
"The Prequel version of hypochlorous acid is called Universal Skin Solution to denote how universal it can really be. I really love the spray mechanism on this, one issue I found with hypochlorous acid sprays in the past is you don't get a nice fine mist when you spray, it's more of a squirt, and so I really find that this has a beautiful application on the skin. I do want to make it very clear that the Prequel hypochlorous acid is not considered a drug, it is really a cosmetic, so we really think of it as calming, soothing, purifying the skin, but it is not a treatment or cure for things like acne or rosacea."
Dermatologist Explains Hypochlorous Acid: How to Use it in Your Skincare Routine | Dr. Sam Ellis
"I'm such a fan of hypochlorous acid and I've seen so many of my own patients benefit from it over the years, so it was really important to me that when I created my own skincare brand Prequel, we had a hypochlorous acid product as well. The Prequel version is called Universal Skin Solution to denote how universal it can really be. I really love the spray mechanism on this because one issue I found with hypochlorous acid sprays in the past is you don't get a nice fine mist when you spray, it's more of a squirt, and so I really find that this has a beautiful application on the skin. I do want to make it very clear that this is not considered a drug; it is a cosmetic, so we really think of it as calming, soothing, and purifying the skin, but it is not a treatment or cure for things like acne or rosacea."
GRWM Skincare & Makeup Routine: Sharing Our Trip to Japan (Tokyo & Kyoto) | Dermatologist
"This is so amazing for like sensitive irritated skin. If you have irritated skin, if you have reactive skin, it's just fantastic."
Introducing Prequel's NEW Hypochlorous Acid Spray, Universal Skin Solution | Dr. Sam Ellis
"This skin solution spray has hypochlorous acid, and hypochlorous acid is something that I use in my practice many many times a day pretty much on every single patient that I'm doing any type of procedure on. Hypochlorous acid is an antimicrobial ingredient that we really use to cleanse the skin, reduce inflammation, and prepare it for any treatment. For many years doctors just use alcohol to prep skin for procedures, but as we all know alcohol can be irritating and drying, and so there's been this big shift towards hypochlorous acid, which has all of those great antimicrobial properties but without the irritation that can come with alcohol or other cleansers. Hypochlorous acid is something that dermatologists have been recommending to patients with eczema and atopic dermatitis for years because it really helps reduce inflammation on the skin and remove microbial agents that can be irritating or cause inflammation. Even though I use hypochlorous acid spray in my clinic all the time to prepare my patients for procedures, it's not just a cleanser, it is a multi-purpose spray that you can use in your day-to-day life to accomplish so many things when it comes to skin care. I really wanted a hypochlorous acid spray in Prequel's lineup because of its versatility, and I feel like there are so many people out there who have sensitive skin who want to cleanse their skin, prep their skin, soothe their skin."
Introducing Prequel's NEW Hypochlorous Acid Spray, Universal Skin Solution | Dr. Sam Ellis
"I find that when I incorporate this into my routine my skin just feels more fresh over the course of the day it looks calmer my pores look more refined it actually does a lot more than I even ever expected it to do. I like to use this hypochlorous acid spray before I go in with any of my serums sunscreen. It's perfect for that soothing and visual reduction in redness without having to put a thick layer of another product. I also feel like it really is great for reviving the skin throughout the day because you can spray this on top of sunscreen on top of makeup to sort of refresh and also calm the soothe the skin. I also personally think this is a gym bag staple because you can use it to prep your skin before a workout but also afterward if you can't jump in the shower right away spraying it in the armpits or on your chest and back places where you might be prone to congestion or texture. Hypochlorous acid is effective yet gentle and I think sometimes when people hear the word acid in anything they just assume that it could irritate their skin but hypochlorous acid is different and especially at this concentration it is gentle."
Introducing Prequel's NEW Hypochlorous Acid Spray, Universal Skin Solution | Dr. Sam Ellis
"You can use it on your face and your body and really get all of the value that you need from it. Dermatologists have understood that hypochlorous acid is incredible, and I want to help you understand how to use hypochlorous acid to be the most beneficial for you. This mist when I tell you it is so fine, you put it on your skin it sits there for a second and then it flashes off so that you're not really sitting there wet or sticky from its application. It just makes it so easy to use on the go. We formulated the skin solution spray to be incredibly stable because hypochlorous acid can be a little bit finicky and it is so important that the processing is correct so that that hypochlorous acid remains effective in solution and can continue to work its magic in the packaging and then when it's on the skin. I like to put it on after the shower, I towel dry after the shower I spritz it on especially in my armpits because I don't love wearing antiperspirant all the time and this is a really nice way for me to control body odor. I spray it on my face, usually one two one two like three spritzes on my face, it dries down in like two seconds and then I go in with my antioxidant usually my vitamin C. A lot of people wonder can you use something like hypochlorous acid and then follow it up with an antioxidant like vitamin C and yes you can, you just have to let this one dry which happens pretty much instantaneously and then you can proceed with the rest of your routine. I also like to have one of these in my to-go bag because it is really nice to refresh the skin midday."
Introducing Prequel's NEW Hypochlorous Acid Spray, Universal Skin Solution | Dr. Sam Ellis
"This is formulated with electrolyzed water and hypochlorous acid, and that balance has to be perfect to ensure that it does everything that you want it to. It's also formulated with a soothing mineral concentrate which is a little bit higher in magnesium to really ensure skin hydration when this is applied. Someone might look at a hypochlorous acid spray and say oh that's just bleach and water, no, it's so much more than that. You have to get the perfect concentrations, you have to stabilize it, and this is really a hero product that I feel like has been undervalued for so long. You can use it everywhere, it's great for sensitive skin. This product is fragrance free, alcohol free, pH stabilized, safe for all skin types, safe for those who have sensitive skin and eczema and psoriasis. It's really meant for all skin. This is something that's part of my everyday life both in my Dermatology office and outside the office."
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