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Prequel

Retinal Renew Retinaldehyde Gel 0.1%.

Prequel Retinal Renew Retinaldehyde Gel 0.1%
Retinoids

About this product

A retinaldehyde gel in 0.1% and 0.2% strengths designed to provide retinoid benefits in a lightweight formulation.

Guru Score

86%

Yay

6 experts · Moderate agreement
Guru Certified
Broad expert consensus
6Gurus
6Yay
0Mixed
0Nay

What they liked

  • Lightweight gel that absorbs without heaviness
  • Fragrance-free and affordable
  • Available in two strengths

What they flagged

    Nothing. None of the experts who reviewed it raised a problem.

    What the gurus are saying

    This retinaldehyde gel earns praise for feeling lightweight and hydrating rather than drying, despite containing an active retinoid. The formula delivers barrier support through ceramides, peptides, and squalane, making it comfortable for consistent use. Available in two strengths, fragrance-free, and at an accessible price, it appears particularly well-suited for anyone new to retinoids or those who've struggled with harsher formulations.
    Synthesized from 6 expert reviews · most recent take September 2026

    What the gurus are saying.

    Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

    All takes Yay takes Nay takes Mixed takes Hide sponsored
    Yay
    "Prequil is absolutely amazing. Their Retinol Renew Retinohyde gel is 29 bucks and comes in two strengths, 0.1 and 0.2. It's wonderful because it has ectoine in it to help soothe skin so you don't experience retinization. Plain tretinoin is full of denatured alcohol and can be very drying and difficult to get started on. This makes it so easy to get into the rhythm of using it without the dryness, flakiness, and peeling."
    All 7 takes from No BS Beauty
    Evening Firming & Anti-Aging Skincare Routine🌙🌜 Dry Sensitive Skin
    "There's a lot of great retinols out there. This one is just one that I've happened to be really enjoying. It's orange. Some people do not like that. I don't mind it because I'm usually using this right before I go to bed. If a little bit of orange gets on my clothes, I just wash them out, but other people did not have that same outcome. They said it stained things. I didn't notice it staining anything of mine, but I don't have fancy sheets or anything."
    Best New Skincare Products So Far This Year
    "If you're newer to retinol, I would start with the 0.1. If you're experienced with retinol and retinoids, you probably go with the 0.2 or you could mix the 0.2 with a little bit of moisturizer as well to help and layer it with moisturizers to prevent dryness. It's got haba oil, it has ectoine, great antioxidant. Ectoine is great at everything. Vitamin E and then rice bran extract. No fragrance or alcohol in here. I'm loving all these new releases so far this year. I can see these being in my routine for a long time because they each offer something unique to my skin that a lot of products don't have."
    New Skincare Products Released- CeraVe Brightening Lotion, Prequel Retinal, PC, Medik8, Cosrx, FAB
    "It's got .1% retinaldehyde and then 2% retinaldehyde. $29 and $35. And it's fragrance free. It's got ectoine in there, retinyl alginate 20, and then it's also got rice bran extract and jojoba oil. I like the fact that it's in two strengths, fragrance-free and pretty affordable."
    Ranking Dermatologist-Founded Skincare Brands - Not All Derm Brands Are Created Equal
    "Also the new retinalehyde is also worth checking out. I just picked this up recently. So, uh hope to review it soon, as soon as possible. But, uh another nice product."
    Prequel 🆕 Retinal Renew Retinaldehyde Retinoid Gel Review, How to Use, Dupes & Alternatives
    "I gave this one a 10. It's got a lot to like about it. It's a pretty nice product. Definitely will finish it. I do like the fact that it's a little bit bigger packaging. It's pretty darn nice and it's a good product overall."
    Best Drugstore Anti-Aging Skincare Products 💪 Affordable Ways to Fight Wrinkles 🙌 Anti Aging Week
    "Prequel's Retinol Renew Retinol Hide Gel is $29. It comes in two strengths, 1% or 2%, I've got the 2%. It's great for fighting fine lines, wrinkles, if you have acne, pores, oily skin. In addition to the retinol, it has ectoin for soothing, jojoba oil, centella, and vitamin E. It helps smooth skin texture, skin appears firmer, improves skin clarity and skin tone, combats the appearance of pores, and helps fight aging and signs of fine lines. I really love this one, it's certainly worth checking out at Target or at Prequel."
    5 Ingredients to Boost Collagen & Firm Skin! Anti-Aging Products I'm Using that Reduce Saggy Skin
    "Prequil is absolutely amazing. Their Retinol Renew Retinohyde gel is 29 bucks and comes in two strengths, 0.1 and 0.2. It's wonderful because it has ectoine in it to help soothe skin so you don't experience retinization. Plain tretinoin is full of denatured alcohol and can be very drying and difficult to get started on. This makes it so easy to get into the rhythm of using it without the dryness, flakiness, and peeling."
    Yay
    "They suggest using the Half and Half as a moisture sandwich with their retinaldehyde, which I 10 out of 10 recommend. That has to be one of my favorite Prequel products and they have a lot of great gems. Retinaldehyde can be a little irritating in the beginning, although it's generally well tolerated, and I find the base of that retinaldehyde is amazing as a moisturizer, it's beautiful. That has to be one of the best products I have tried out this year, I'm not exaggerating. It's going to make an appearance in my best of series most likely towards the end of the year."
    All 4 takes from Dr Dray
    Dermatologist Reviews Prequel Pre-Gleanse Cleansing Oil
    "I love Prequel. They have many fantastic products. Watch my video of their retinaldehyde because that is a really good product. And you're going to want to hear all about retinaldehyde and what it can do for your skin."
    Prequel Retinal Review | Better Than Retinol?
    "Overall, I feel as though Prequel did an excellent job on this formulation. Everything from the backbone with the ectoin, the B12, the nice lightweight gel texture, the fragrance-free, the delivery system, and I also really love actually the price point because let's be honest, that is pretty competitive amongst the different retinaldehyde products we have available. It's not the cheapest, but there are certainly retinaldehyde products in the 50s, the 60s, the $100 price point range."
    I Finished These Skincare Products... Here's My Verdict
    "This has been added to the retinols and retinaldehydes I recommend. This is a lovely, lovely formula. In addition to the retinaldehyde, it's got cica, compounds from centella which are anti-inflammatory, and it has ectoin, an extremolyte that's hydrating and antioxidant. This is the 0.1% retinaldehyde gel, they also make a 0.2%, but I would not put too much stock in those being drastically different. They're really really good for your moisturizing needs and very rich, and I ended up using this in the morning too since you can use retinol in the morning, it's not completely off the table. Really really like this."
    Dermatologist Reviews Prequel Half & Half Moisturizer
    "They suggest using the Half and Half as a moisture sandwich with their retinaldehyde, which I 10 out of 10 recommend. That has to be one of my favorite Prequel products and they have a lot of great gems. Retinaldehyde can be a little irritating in the beginning, although it's generally well tolerated, and I find the base of that retinaldehyde is amazing as a moisturizer, it's beautiful. That has to be one of the best products I have tried out this year, I'm not exaggerating. It's going to make an appearance in my best of series most likely towards the end of the year."
    Yay
    "I don't personally use this because I already use adapalene, but my partner started using the 0.2% and it's been absolutely amazing to watch her skin transform. She's tested other retinoid products since and isn't liking them as much as this, this one was the best she has tried. 0.2% is a strong level, so if you're new to the ingredient you might want to start with the 0.1% instead."
    All 2 takes from AliceintheRabbitHole
    HONEST Ranking of Prequel Skincare (Too Honest?)
    "I don't personally use this because I already use adapalene, but my partner started using the 0.2% and it's been absolutely amazing to watch her skin transform. She's tested other retinoid products since and isn't liking them as much as this, this one was the best she has tried. 0.2% is a strong level, so if you're new to the ingredient you might want to start with the 0.1% instead."
    New Skincare, Infuriating Tariffs, & Reactions! | Dec 2025
    "I'm so excited that Prequel has come out with what I'm thinking will be an accessible retinaldehyde product, in two strengths, 0.1% and 0.2%, with a complex that includes retinaldehyde, ectoin, bioactive seca, and glycerin. It's also 1.7 fluid ounces, a larger size, so on a technicality this actually is a better price point than the comparable Geek and Gorgeous version. This is newer to me, and like with all retinoid products you have to give it several months to see what it really does for your skin, but I've made a decision to go with the lower strength 0.1% version and add it into my routine combined with my adapalene. I think I'm finally ready for that."
    Yay
    "This actually does a really nice job protecting the skin barrier and feeling nice and lightweight on the skin so that you can follow it up with whatever else you have in your skincare routine without causing like peeling or too much issues there. I find this very agreeable on sensitive skin, redness prone skin. I am not worried that this is going to flare it up and make it much worse. It's very gentle. So the 0.1% that's where I'd recommend to start, especially if you've never used retinoids. You don't even have to go up to the 0.2%. If you want to, sure, and it's not causing irritation, yes. But definitely at least start with the lowest option first."
    Yay
    "The first one I want to recommend is the new release by Prequel. The ingredients in this formula include ceramides, peptides, it also has squalane. So, a lot of barrier support within a retinol formula. I wouldn't bump up to the 0.2. Just stick with their 0.1 formula."
    All 2 takes from Beyond50Skin
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    "Their new retinaldehyde is a very gentle formula. I've had no problems using it."
    STOP! Buying the Wrong Retinol: My Honest Ranking of the 5 Best for Mature Skin Over 50
    "The first one I want to recommend is the new release by Prequel. The ingredients in this formula include ceramides, peptides, it also has squalane. So, a lot of barrier support within a retinol formula. I wouldn't bump up to the 0.2. Just stick with their 0.1 formula."
    Yay
    "If you're shopping outside of Sephora, my brand Prequel has a 0.1% and a 0.2% retinaldehyde. For people who maybe want something a little bit more potent or are looking to amp up their routine but are either not ready for or don't have access to prescription tretinoin, all good options."
    SponsoredFounder's own brand
    All 5 takes from Dr. Sam Ellis
    Makeup + Retinol: The Hidden Conflict You’re Ignoring | Dr. Sam Ellis
    "I had a patient very recently who I've been seeing for years, and for the past like six months, every time she came in, I just felt like her skin looked kind of dry and flaky. And she was like, 'I cannot use my tretinoin successfully, and I've tried all the things you recommended.' And so what we did is we dropped her down to the retinaldehyde from Prequel, which is a newer product, and it's less intense. And she's tolerating it now beautifully. She's so happy with how her skin is doing. I do this all the time for my patients. I will transition them from tretinoin down to retinol or retinaldehyde. That is not a failure. That is a redirection. It's the whole reason with Prequel I wanted to create a retinaldehyde product because I had so many patients struggling to tolerate their tretinoin either on their face or on their neck and chest. And I wanted them to have options where they could still be really successful and see great anti-aging benefits but not put their skin through it constantly with tretinoin."
    Best Anti-Aging Game-Changers of 2025 (Dermatologist Approved)| Dr. Sam Ellis
    "The retinaldehyde gel that we put out this year is the retinoid of the year. If you're not familiar with retinaldehyde, it sits right between retinol and tretinoin on the retinoid spectrum. So it is more potent than retinol, it works faster than retinol, but it's not as intense as tretinoin. And tretinoin is available by prescription only. Since the conception of Prequel, I really wanted to launch a retinaldehyde product, but we had to work with it to get a really special formula that was non-irritating but also produced results. When we finally got this gel to work exactly how I wanted it to, it was so exciting to me. Although I use tretinoin on my face and have for ten plus years, I could never tolerate tretinoin on my neck or on my chest. It was just too irritating there. So to have my own retinaldehyde product that still helps me maintain the skin in these areas, which is very important to do, but not have irritation, I'm so happy. A lot of my patients also can't tolerate tretinoin on their face. I would love if everyone could use tretinoin because that is the gold standard. It has been the most studied molecule ever when it comes to anti-aging, maybe besides sunscreen. But there are people who just cannot use it without getting flaky or irritated."
    Introducing Prequel's NEW Retinal Renew Retinaldehyde Gel 0.1% & 0.2% | Dr. Sam Ellis
    "I have used retinaldehyde in my own skincare routine for years and recommended it to my patients and I find it to be such an all-star ingredient. I really wanted to create a retinoid formula that not only delivered real results but also respected the skin barrier and was easy to incorporate into a skincare routine. The main active ingredient is retinaldehyde, which is one of the most potent forms of vitamin A you can get without a prescription. It supports healthy skin cell renewal and visibly brighter and smoother looking skin. It's also been shown to help boost skin's collagen production, which helps with firmness and combating things like fine lines and wrinkles. When you compare retinaldehyde to retinol, studies show that both are quite gentle on the skin and significantly less irritating than prescription retinoids. But retinaldehyde only needs to undergo one conversion step within the skin to reach its active form, while retinol needs to undergo two conversion steps."
    My Real Routine: What I Tell Patients vs. What I Do Myself | Dr. Sam Ellis
    "I will use an over-the-counter retinol or retinaldehyde on my neck and chest. And really, that is one of the driving reasons why Prequel made a retinaldehyde product. I wanted something that I could use on my neck and chest. I had used ones from other brands that were great, but it's always nice to do it yourself. And aside from this formula being incredible and not irritating to my neck or chest, it's also effective and super affordable. If you're someone who can't tolerate prescription strength tretinoin, and there are many people out there like that, it's okay. You can still use retinol or retinaldehyde and have wonderful anti-aging benefits."
    Products I Would NEVER buy at Sephora as a Derm | Dr. Sam Ellis
    "If you're shopping outside of Sephora, my brand Prequel has a 0.1% and a 0.2% retinaldehyde. For people who maybe want something a little bit more potent or are looking to amp up their routine but are either not ready for or don't have access to prescription tretinoin, all good options."

    Frequently asked.

    What is Prequel Retinal Renew Retinaldehyde Gel 0.1%?

    A retinaldehyde gel in 0.1% and 0.2% strengths designed to provide retinoid benefits in a lightweight formulation.

    Is Prequel Retinal Renew Retinaldehyde Gel 0.1% worth it?

    Yes. All 6 gurus who reviewed it give it their stamp of approval, for a Guru Score of 86%.

    What is Prequel Retinal Renew Retinaldehyde Gel 0.1%'s Guru Score?

    Prequel Retinal Renew Retinaldehyde Gel 0.1% holds a Guru Score of 86%. That is our read on how warmly the experts talk about it, based on the verdicts of 6 expert reviewers we have collected. It is also Guru Certified, our mark for products that hold broad approval across many expert reviewers.

    Who is Prequel Retinal Renew Retinaldehyde Gel 0.1% best for?

    Prequel Retinal Renew Retinaldehyde Gel 0.1% is generally suited to acne-prone skin and mature skin.

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