Index / Prequel / Barrier Therapy Skin Protectant Cream
Prequel

Barrier Therapy Skin Protectant Cream.

Prequel Barrier Therapy Skin Protectant Cream
Moisturizers

About this product

A barrier-repair cream from Prequel with ceramides, formulated to soothe and protect dry, compromised skin on both the face and body.

Best for

Dry skinSensitive skin
Moisturizers

The Guru Index verdict

83%

Approved

Approved · 83%
5Reviewers
5Approved
0Mixed
0Skip

What the gurus are saying

Gurus unanimously praise this cream for delivering serious barrier repair without the heaviness typical of such products. It's repeatedly highlighted as exceptional for irritated, eczema-prone, or rosacea-affected skin, with users reporting visible calming and redness reduction. The ceramide-rich formula, modest price point (around $18), and large tube size are consistent wins. Reviewers note it spreads easily, hydrates without greasiness, and works well alongside actives like retinoids. The only minor caveat is that those seeking a very rich, heavy cream might find it slightly lightweight.
Synthesized from 5 expert reviews

Key actives & flags

Vitamin ECeramidesFragrance-freeAlcohol-free

Full ingredients

Colloidal Oatmeal (1.0%), Water (Aqua), Carthamus Tinctorius Seed Oil, Cetyl Alcohol, Glycerin, Butyrospermum Parkii Butter, Caprylic/​Capric Triglyceride, Dimethicone, C10-18 Triglycerides, Allantoin, Adenosine, Cetearyl Olivate, Sorbitan Olivate, Ceramide AP, Ceramide EOS, Ceramide EOP, Ceramide NP, Ceramide NS, Cholesterol, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Glycolipids, Phospholipids, Sodium Stearoyl Glutamate, Behenic Acid, Ceteareth-25, Glycine Soja Oil, Glycine Soja Sterols, Carbomer, Phenoxyethanol, Ethylhexylglycerin, Tocopheryl Acetate, Tetrasodium Glutamate Diacetate, Sodium Chloride, Sodium Hydroxide

Every take, in full

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Approved only Skip only Mixed only Hide sponsored
Approved
"It's their barrier therapy skin protectant cream. This is an awesome face and body lotion. It's a really nice cream that does contain ceramides. It's also got urea. Comes in a 10 oz tube and it's a great price point."
All 3 takes from HotandFlashy
Get Rid of DRY FLAKEY DULL Winter SKIN For Good!
"It's their barrier therapy skin protectant cream. This is an awesome face and body lotion. It's a really nice cream that does contain ceramides. It's also got urea. Comes in a 10 oz tube and it's a great price point."
How To FIX Crepey Skin! What I Use To Keep Crepey Skin Away At 62!
"This is their barrier therapy skin protectant cream, this is a really great body lotion to have in your arsenal because this contains serum eyes, it's got five ceramides plus the cholesterol that it needs to actually deliver the ceramides into your skin. This is a very soothing lotion that's going to help to repair your skin barrier. It's got colloidal oatmeal in it, it also has shea butter and glycerin. Of the three, this is going to be the more lightweight of the three lotions, easier to spread."
Counting Down The BEST SKINCARE of 2024!
"The Prequel Barrier Therapy Skin Protectant Cream is calming and soothing for the skin, it's good for eczema skin or itchy skin, but what I love about this is that it has ceramides in it and it's so hard to find a body product that has ceramides. This contains five ceramides, so this has gotten into my rotation of body lotions that I use every time I get out of the shower. It comes in a nice big 10 oz tube and the Prequel pricing is very reasonable."
Approved
"This is the barrier therapy skin protectant cream. This is your dermatologist approved and created option. I would say it's not like glamorous, but it's also not sterile and clinical in any way. It's kind of that good in between. It's just incredibly effective, especially if your skin is pissed off, angry, irritated. We have 1% colloidal oatmeal in here. That's a great skin protectant. Helps with itching, irritation, eczema flare-ups. I think this is approved by the eczema society or something. It's great for rosacea, kind of providing this protective barrier and soothing the skin. We have beta glucans and allantoin in here as well to soften the skin, calm irritation, ceramides to help strengthen the skin barrier and support its resilience. And then we have a lipid complex of ceramides, cholesterol, and fatty acids, which is basically like the perfect ingredient that is going to mimic your natural barrier. For the price, it's such a bargain."
Top Pick: barrier therapy cream
All 4 takes from James Welsh
Testing 5 ✨ AMAZING 🌙 Overnight Masks for Better Skin by Morning
"This is the barrier therapy skin protectant cream. This is your dermatologist approved and created option. I would say it's not like glamorous, but it's also not sterile and clinical in any way. It's kind of that good in between. It's just incredibly effective, especially if your skin is pissed off, angry, irritated. We have 1% colloidal oatmeal in here. That's a great skin protectant. Helps with itching, irritation, eczema flare-ups. I think this is approved by the eczema society or something. It's great for rosacea, kind of providing this protective barrier and soothing the skin. We have beta glucans and allantoin in here as well to soften the skin, calm irritation, ceramides to help strengthen the skin barrier and support its resilience. And then we have a lipid complex of ceramides, cholesterol, and fatty acids, which is basically like the perfect ingredient that is going to mimic your natural barrier. For the price, it's such a bargain."
Best Skincare / Beauty Products Of 2023 - Skin, Hair, Fragrance, Best Brand! 💜 James Welsh
"It just glides on. It's somehow hydrating, yet thick enough to feel like you're using a Ceramide cream. It just suits both perfectly for face and body. Once I finished my other creams, I jumped on this one because it's huge. 260ML for $18. My skin just loves it. My rosacea has transformed to the point where I can happily sit on camera without wearing a tinted sunscreen and any makeup. I don't get asked what my redness is anymore. Those comments about why is your nose red, why are your cheeks so red, I just barely get them anymore. And that just happens to coincide with using this product."
No B.S Skincare Products That JUST WORK!
"I find barrier healing and repairing creams to be quite suffocating, quite thick, quite boring to use, especially as somebody who loves dewy, glowy skin. They often don't give you that glow that you want. But not only does this feel incredibly hydrating and look hydrating on the skin, it's also almost like instantly soothing and calming and repairing. They've got their 1% colloidal oatmeal in here which is going to help soothe the skin, moisturize the skin if it's dry, if it's itchy, if it's flaky, or if you just had a reaction to a product or anything basically. It has this instant soothing and cooling sensation to it. Allantoin in here as well to help moisturize the skin and then multi-ceramides too, so providing barrier support. It's just such a pleasant product to use and for the price, $18 for 296 ml, that's so good. There is so much for such a decent price. If my skin is destroyed and it needs to repair, other than my Aura ataro cream, this is the one I go for for a guaranteed quick repairing and healing kind of product."
No B.S Skincare Products That JUST WORK!
"It has 1% colloidal oatmeal in here which is going to help soothe the skin, moisturize the skin if it's dry, if it's itchy, if it's flaky, if you just had a reaction to a product or anything basically, or we're going into cold weather and your skin's messing up. It has this instant soothing and cooling sensation to it. Allantoin in here as well to help moisturize the skin and then multi-ceramides too so providing barrier support. It's such a pleasant product to use and for the price, $18 for 296 ml, that's so good. If my skin is destroyed and it needs to repair, other than my Aura Ataro cream, this is the one I go for for a guaranteed quick repairing and healing kind of product."
Approved
"It is very lightweight, it is not a super rich heavy cream, so if you're somebody who likes a really rich thick formula this maybe a little too on the lightweight side for you. It did leave my skin feeling moisturized and hydrated, didn't dry down with a tight film. The following day my skin was moisturized. It doesn't feel greasy, sticky, there's no odd residue."
Approved
"This is their barrier therapy skin protectant cream. If you want a one-and-done, you don't want to think about your body care, you just want to get out and put on one thing. It's got niacinamide, copper tripeptides, hyaluronic acid, squalane, ceramides, mandelic acid, maltobionic acid for smoothing texture, and prebiotics. This is your all-in-one. It has a slightly funky smell, but it's just the products in here. I love this. If I just want a no-brainer, just want to jump out of the shower, throw something on, and know that I'm doing a really good job at protecting the skin barrier on my body, this is the one I've been reaching for."
Sponsored
All 2 takes from Beyond50Skin
WINTER SKIN SURVIVAL KIT ❄️ Stop Trans-Epidermal Water Loss (TEWL) for Mature Skin Over 50 Skincare
"This is their barrier therapy skin protectant cream. If you want a one-and-done, you don't want to think about your body care, you just want to get out and put on one thing. It's got niacinamide, copper tripeptides, hyaluronic acid, squalane, ceramides, mandelic acid, maltobionic acid for smoothing texture, and prebiotics. This is your all-in-one. It has a slightly funky smell, but it's just the products in here. I love this. If I just want a no-brainer, just want to jump out of the shower, throw something on, and know that I'm doing a really good job at protecting the skin barrier on my body, this is the one I've been reaching for."
All The Beauty & Skincare Products I Got In February (Beauty Over 50)
"I also purchased Prequel Barrier Therapy Skin Protectant Cream. It's supposed to help with dry skin, itchy skin, eczema prone skin and has 1% colloidal oatmeal. I'm super excited to try this. I haven't tried this yet because I'm trying and testing a ton of body lotions for you guys coming up, but you get a huge bottle."
Approved
"The Prequel Barrier Therapy Skin Protectant Cream is a moisturizer that was really designed for face and body. It has oatmeal in it to help soothe the skin, but the reason I love this so much and the reason I'm bringing it into this routine is the number of DMs I've gotten on Instagram saying this is the product that helped me tolerate my retinoid better, this is the product that allowed me to finally use tretinoin or retinaldehyde or whatever has been like overwhelming."
SponsoredFounder Conflict
All 2 takes from Dr. Sam Ellis
Introducing Barrier Therapy, A Rich Skin Protectant Cream For The Face & Body | Dr. Sam Ellis
"This contains a lantoine which I absolutely love it moisturizes and soothes the skin and also adenosine which has similar properties. This is truly a rich velvety luxurious cream that you can apply head to toe. I find that for so many of my eczema patients and other patients who I recommend regular moisturization to, they're really hesitant to use body lotions because they don't like any residue on their skin or they don't want it to feel heavy, and I feel like this is such a perfect balance of rich nourishing cream that doesn't leave that kind of residue. It's not just about the ingredients, it's about the formula overall and creating something that people are inspired to use, that they want to use on their body so that they can be consistent because ultimately it is about being consistent with your skin in order to get it to its healthiest state. You can use this on your face and your body so if you're experiencing any types of irritation or sensitivity this is amazing, but also if you just need a day-to-day head to toe moisturizer this is fantastic. This cream is really amazing if your skin is feeling at all sensitive in any way or if you're craving something a little bit more rich and silky."
Dermatologist's Affordable Anti-Aging Skincare Routine for Sensitive Skin | Dr. Sam Ellis
"The Prequel Barrier Therapy Skin Protectant Cream is a moisturizer that was really designed for face and body. It has oatmeal in it to help soothe the skin, but the reason I love this so much and the reason I'm bringing it into this routine is the number of DMs I've gotten on Instagram saying this is the product that helped me tolerate my retinoid better, this is the product that allowed me to finally use tretinoin or retinaldehyde or whatever has been like overwhelming."
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