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Plated Skin Science

Plated Skin Science Daily Anti-Aging Exosome Serum.

Plated Skin Science Daily Anti-Aging Exosome Serum
Serums
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About this product

A gel-textured serum with human-derived exosomes and platelet extract formulated to improve fine lines, wrinkles, and redness while supporting faster post-treatment skin recovery.

Guru Score

73%

Mixed

4 experts · Moderate agreement
4Gurus
2Yay
2Mixed
0Nay

What they liked

  • Gel texture, dries down cleanly
  • A little goes a long way
  • Works well under makeup and sunscreen

What they flagged

  • Very expensive for bottle size
  • Exosome sourcing and efficacy still unclear

What the gurus are saying

This serum's human-derived exosomes deliver visible improvements in fine lines and wrinkles, with reviewers noting instant plumping effects, but the $255-265 price for just 15ml is a major sticking point. It pairs especially well with post-treatment skin or microneedling, where gurus report faster healing. Not all reviewers felt convinced the results justified the cost, but those committed to the expense report genuine effectiveness for fine lines.
Synthesized from 4 expert reviews · most recent take July 2026

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored
~Yay
"The daily serum comes in a silver bottle. I use it more sparingly, kind of similar to the SkinMedica, just around my eyes and mouth and areas, sometimes between my eyebrows. This uses their human platelet exosomes, and it's kind of interesting how they do that, but it's a really nice product. The human platelet exosomes I found are really nice and helpful, great if you use lasers at all or micro needling. I really like to use these after micro needling. This one's a nice one, simple product."
All 6 takes from No BS Beauty
Plated Skin Science Daily Anti-Aging Exosome Serum Review, How to Use, Dupes & Alternatives
"Over time using this, it does seem to help with the appearance of fine lines and also seems to help plump skin up a bit. It seems to work well under sunscreen in the daytime or in my evening routine. It works great doing both of those. [...] This one has less of a siliconey texture than [...] the intense serum. For what this product promises to significantly minimize the appearance of wrinkles, redness and brown spots, and offer hydration, I would say it does all of those."
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"This is a gel serum that replenishes hydration and supports continuous renewal. The star of the show for this one is their human platelet extract, which is kind of interesting. The Plated Company is located across from the Mayo Clinic in Rochester, Minnesota, and they get donated blood donations that are close to expiring. [...] They get ones that are on their way out, not going to be used, and then they extract the exosomes from those blood samples."
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"Out of a 10, I gave this a nine. This would be a 10 out of 10 if I could get it for free."
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"This one's 1 oz for 258 bucks, so it's a little bit more affordable. This one basically just contains a higher amount of the human platelet exosomes. The [...] daily serum contains 10 million exosomes, so the intense is a little bit stronger. The daily serum is nice. This one has more of a siliconey texture to it though, so it doesn't go as far. You can't make one pump go as far as you can with the intense serum, but it is more affordable."
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"It works really nicely right under sunscreen or makeup. I think it's got a silicone in it so it [...] gives it that nice kind of sheen that looks like a good primer. And in addition to the Exosomes it's got arginine and cilantro oil which is a great antioxidant. So, really nice product."
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"The daily serum comes in a silver bottle. I use it more sparingly, kind of similar to the SkinMedica, just around my eyes and mouth and areas, sometimes between my eyebrows. This uses their human platelet exosomes, and it's kind of interesting how they do that, but it's a really nice product. The human platelet exosomes I found are really nice and helpful, great if you use lasers at all or micro needling. I really like to use these after micro needling. This one's a nice one, simple product."
~Yay
"A lot of patients post treatment that use it say they feel like their skin heals a lot quicker, but that also is maybe attributing to the anti-inflammatory, getting rid of redness. I think it's the future. [...] But I would knock one or two off because they're damn expensive. But it's replacing some other stuff if you look at it like that. So we carry the Plated exosomes in the office and you've seen some patients who've used that."
~Mixed
"And I knew some derms who carried it in their office and I was like, "Oh, that feels pretty legit." So I used it every day for 3 months. And I do feel like it helped with the redness of my rosacea and maybe my skin looked a little bit less textured, but it wasn't enough of an impact for me to feel like, yeah, I feel confident recommending this or selling this to my patients. So for me right now, it's kind of TBD when it comes to exosomes."
~Mixed
"It's $267, so definitely not cheap, and it's hard to tell from their website where the exosomes are derived from. Because exosomes are secreted by all cells as well as body fluids, we can find them in blood, breast milk, and amniotic fluid. They're commonly used in skin care and regenerative medicine, usually derived from some sort of stem cells or bone marrow cells. So you can see there is a potential concern for their novelty and ethically where they're derived from."

Frequently asked.

What is Plated Skin Science Daily Anti-Aging Exosome Serum?

A gel-textured serum with human-derived exosomes and platelet extract formulated to improve fine lines, wrinkles, and redness while supporting faster post-treatment skin recovery.

Is Plated Skin Science Daily Anti-Aging Exosome Serum worth it?

The gurus mostly approve it, but with enough reservations to keep it in the middle at a Guru Score of 73%.

What is Plated Skin Science Daily Anti-Aging Exosome Serum's Guru Score?

Plated Skin Science Daily Anti-Aging Exosome Serum holds a Guru Score of 73%. That is our read on how warmly the experts talk about it, based on the verdicts of 4 expert reviewers we have collected.

Who is Plated Skin Science Daily Anti-Aging Exosome Serum best for?

Plated Skin Science Daily Anti-Aging Exosome Serum is generally suited to mature skin.

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