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Peter Thomas Roth

Peptide Skin Injection Moisture Infusion Cream.

Peter Thomas Roth Peptide Skin Injection Moisture Infusion Cream
Serums

About this product

A peptide-enriched moisturizing cream designed to hydrate, plump, and target fine lines and signs of aging with a multi-peptide formula.

Guru Score

76%

Yay

Early verdict · Few reviews so far
2Gurus
1Yay
1Mixed
0Nay

What they liked

  • Absorbs richly without feeling heavy
  • Hydrates and plumps skin throughout the day
  • Suitable for morning and evening use

What they flagged

    Nothing. None of the experts who reviewed it raised a problem.

    What the gurus are saying

    The 21 peptides and neuropeptides work together to smooth expression lines, enhance elasticity, and improve skin texture and radiance while delivering deep hydration that leaves skin feeling plump and nourished. Dr. Aleksandra Brown, who has reviewed this multiple times, finds it suitable for both day and night use and particularly favors it for mature skin, though the formula is rich enough that those with very oily skin may want to test it first to ensure it layers well with their routine.
    Synthesized from 2 expert reviews · most recent take October 2025

    What the gurus are saying.

    Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

    All takes Yay takes Nay takes Mixed takes Hide sponsored
    Yay
    "My other recommendation in this category is the Peter Thomas Roth Peptide Skin Injection Moisture Infusion Cream. You guys have seen me use this over and over again. I use this actually in the evening. Often I'll use it in the morning as well. It's one of my favorite moisturizers for mature skin. It's formulated with multiple neuropeptides. They're going to help target your wrinkles and enhance elasticity. It's designed to complement really your in-office treatments like Botox for longer lasting results. But if you're somebody who's not getting Botox and you want Botox-like effect, this would be a great moisturizer to accomplish something like that. It helps hydrate but also reinforce the skin's natural structure. This formula includes a blend of 21 peptides and neuropeptides that help smooth the appearance of expression lines and restore that youthful balance to the skin. It also combines both signaling peptides and neuropeptides, two different types of peptides to help slow down some of the wrinkles formed by the movement. The key ingredients are 20 peptides and neuropeptides, the 2% hydrolyzed collagen, hyaluronic acid, and prolamine."
    All 5 takes from Dr. Aleksandra Brown
    Dermatologist Picks: What to Buy (and Skip) at the Sephora Sale | Skincare, Haircare & Makeup Guide
    "This helps hydrate firm and plump the skin. It targets fine lines and signs of aging with this multi-peptide formula. It's really rich but absorbs really well making it suitable for day and night use. And I often wear this twice a day. The key ingredients in this one are the 21 peptides. Also has neuropeptides and hyaluronic acid."
    Dermatologist's Winter Skincare Routine: AM & PM Steps for Healthy Skin | Dr. Aleksandra Brown
    "This is infused with 21 peptides and neuropeptides to help reduce the look of expression lines, enhance skin's natural overall balance, improve elasticity, radiance, and uneven skin tone and texture. It delivers deep hydration and leaves the skin feeling really nourished, supple, and super plump. The 21 peptides and neuropeptides will help further target and smooth the appearance of expression lines. I do love using this in the morning for that purpose. It also has gamma proteins which will help improve skin's elasticity and radiance and even out skin tone and texture. Then it has other hydrating ingredients like cactus flour, squalene, and hyaluronic acid that work together to help hydrate your skin so it looks nice and plump throughout the day."
    Skincare in Your 50s & 60s: Anti-Aging Ingredients, Devices & Dermatologist Tips
    "The Peter Thomas Roth Peptide Skin Injection Moisture Infusion Cream is formulated with multiple neuropeptides to target deep wrinkles and enhance elasticity. It's designed to complement in-office treatments like Botox for longer lasting results. It provides really deep hydration while reinforcing the skin's natural structure. It contains 21 peptides and neuropeptides, 2% hydrolyzed collagen, and hyaluronic acid."
    Derm-Approved Prime Day Skincare Deals You Shouldn’t Miss | What to Buy (and Why)
    "My other recommendation in this category is the Peter Thomas Roth Peptide Skin Injection Moisture Infusion Cream. You guys have seen me use this over and over again. I use this actually in the evening. Often I'll use it in the morning as well. It's one of my favorite moisturizers for mature skin. It's formulated with multiple neuropeptides. They're going to help target your wrinkles and enhance elasticity. It's designed to complement really your in-office treatments like Botox for longer lasting results. But if you're somebody who's not getting Botox and you want Botox-like effect, this would be a great moisturizer to accomplish something like that. It helps hydrate but also reinforce the skin's natural structure. This formula includes a blend of 21 peptides and neuropeptides that help smooth the appearance of expression lines and restore that youthful balance to the skin. It also combines both signaling peptides and neuropeptides, two different types of peptides to help slow down some of the wrinkles formed by the movement. The key ingredients are 20 peptides and neuropeptides, the 2% hydrolyzed collagen, hyaluronic acid, and prolamine."
    Peptides in Skincare: Benefits, Types, and Best Products | Dr. Aleksandra Brown
    "This is the Peter Thomas Roth Peptide Skin Injection Moisture Infusion Cream. This formula has multiple neuropeptides to target those deep wrinkles and enhance some of the skin elasticity. It's designed to also complement in-office treatments like Botox to kind of almost like prolong the effects of it because it works in a similar fashion but applied topically. It provides deep hydration while reinforcing the skin's natural structure. The formula includes a blend of 21 peptides and neuropeptides that help smooth the appearance of those expression lines and restore more youthful bounce to the skin. It combines both signaling and neuropeptides. The key ingredients here are 21 peptides and neuropeptides, the 2% hydrolyzed collagen, hyaluronic acid, and squalane."
    Mixed
    "The Peter Thomas Roth skin injection moisture infusing cream which I have yet to try"

    Frequently asked.

    What is Peter Thomas Roth Peptide Skin Injection Moisture Infusion Cream?

    A peptide-enriched moisturizing cream designed to hydrate, plump, and target fine lines and signs of aging with a multi-peptide formula.

    Is Peter Thomas Roth Peptide Skin Injection Moisture Infusion Cream worth it?

    Mostly yes. 1 of the 2 gurus who reviewed it give it their stamp of approval, for a Guru Score of 76%.

    What is Peter Thomas Roth Peptide Skin Injection Moisture Infusion Cream's Guru Score?

    Peter Thomas Roth Peptide Skin Injection Moisture Infusion Cream holds a Guru Score of 76%. That is our read on how warmly the experts talk about it, based on the verdicts of 2 expert reviewers we have collected.

    Who is Peter Thomas Roth Peptide Skin Injection Moisture Infusion Cream best for?

    Peter Thomas Roth Peptide Skin Injection Moisture Infusion Cream is generally suited to dry skin and mature skin.

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