OneSkin OS-01 Body Topical Supplement: a Guru Score of 86%

Every take, in full

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

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✓Approved

"I've just started using the OneSkin Topical Body Supplement maybe two months ago and I am really impressed with how this product performs on my skin. It really improves skin creepiness, so if you have creepiness above your knee or anywhere on your legs or the backs of your arms, this really does work. It provides your skin with so much hydration, it nourishes the skin, it creates a softer, smoother look, and your skin is always glowing, not a greasy shiny glow, it just looks healthy and repaired. There's a lot of oils in here, different types of butters, ceramides, centella asiatica, and it's fragrance free. It's powered by OS-01, which is the peptide that's proven to reverse biological age. It has that lotion texture, not too runny and not too thick, and a little amount goes a long way so you don't need to use much because it spreads really nicely. Your skin feels nice and moist all day and it isn't sticky or tacky. It's going to improve early signs of aging, prevent fine lines, and improve texture and tone. This is like that one luxury body care product I like to resort to because it makes your skin feel so good, and I honestly haven't found anything like it before, so I really do recommend it."

Darnell Cox | 50+ Healthy Aging Expert

54k subs

✓Approved

"I don't know who else is making it with this particular peptide in it, the OSO1 peptide. This has literally changed my skin. And not just the face one, but the body. This has been a game changer. And in terms of the body one as well, a complete game changer when it comes to treating my body. My OneSkin OS-01 is always like my last thing in terms of the body. For the face, it's always my first thing."

All 2 takes from Darnell Cox | 50+ Healthy Aging Expert

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"I don't know who else is making it with this particular peptide in it, the OSO1 peptide. This has literally changed my skin. And not just the face one, but the body. This has been a game changer. And in terms of the body one as well, a complete game changer when it comes to treating my body. My OneSkin OS-01 is always like my last thing in terms of the body. For the face, it's always my first thing."

Want to know what’s in my Travel Bag?🧳 🎙️Watch my IG Live Show to find what I pack as a healthy

"I don't know who else is making it with this particular peptide in it, the OSO1 peptide. This has literally changed my skin. And not just the face one, but the body. This has been a game changer. And in terms of the body one as well, a complete game changer when it comes to treating my body. My OneSkin OS-01 is always like my last thing in terms of the body. For the face, it's always my first thing."

Skin Obsessed Mary

33k subs

✓Approved

"The OneSkin OS-01 Body Topical Supplement only takes minutes every other day, so it's super easy to fit into my routine. It's become a non-negotiable at this point and it's become a part of my daily routine. I'm even bringing a travel size with me because I'm making sure that I'm really looking after my body properly."

All 3 takes from Skin Obsessed Mary

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"The OneSkin OS-01 Body Topical Supplement only takes minutes every other day, so it's super easy to fit into my routine. It's become a non-negotiable at this point and it's become a part of my daily routine. I'm even bringing a travel size with me because I'm making sure that I'm really looking after my body properly."

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"This has become my holy grail body product. It contains that same OS1 peptide and I can honestly tell you my crepey skin is now gone because of it. I did an isolated test for about 6 months and I was shocked by the results. So yes, I have repurchased."

⭐️ Title

"This peptide helps to reduce those senescent cells but it also helps younger cells to multiply and that's what helps to build collagen to strengthen our barrier and just improve overall skin health. I got their bundle which has the face supplement which I use as a serum, the eye cream as well as the body lotion. I haven't really been using these long enough to truly give my feedback but anecdotally I believe I'm actually seeing a difference particularly on the creepy skin of my arms."

Beyond50Skin

31k subs

✓Approved

"This is necessary the body retinol. Absolutely gorgeous. It's 0.1% retinol, which is a pretty decent percentage. This is one of my holy grails. I keep this in my bathroom all the time. And I layer it up with my OneSkin for the body with the OS-01 peptides for that help with senescent cells. I can't give it up. And honestly I haven't found anything that works better. You can combine this peptide formula with retinol, though you don't want to combine your body exfoliation night with your retinol, but you can combine it with the OS-01 for body. These are both already repurchased. They are sitting downstairs in my bathroom."

All 5 takes from Beyond50Skin

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"This is necessary the body retinol. Absolutely gorgeous. It's 0.1% retinol, which is a pretty decent percentage. This is one of my holy grails. I keep this in my bathroom all the time. And I layer it up with my OneSkin for the body with the OS-01 peptides for that help with senescent cells. I can't give it up. And honestly I haven't found anything that works better. You can combine this peptide formula with retinol, though you don't want to combine your body exfoliation night with your retinol, but you can combine it with the OS-01 for body. These are both already repurchased. They are sitting downstairs in my bathroom."

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"The peptides in this and the skin rejuvenating benefits that I've seen from this are just like no other body lotion I've ever used. I honestly can't skip this in my body care routine."

2025 Body Care for Crepey Skin Over 50 | Holy Grails, New Finds & OneSkin Results!

"This is the revolutionary body treatment that Mary and I have both used, and we are considering it a holy grail. It's the OneSkin OS-01 Body Topical Supplement. I used this exclusively for 3 months, morning and night, none of my other body skincare, just to see what the results would be. This is full of peptides. Whether you just jumped out of the shower or you're just waking up and getting dressed, the OneSkin body goes first in your body skincare routine. It acts to increase and firm the skin barrier. It has a proprietary peptide. This is a step that we don't skip."

6 Months of Skincare Empties | My Husband’s 1st Routine in 60 Years + Results

"One of the body care products that I've been talking a lot about lately is the OneSkin OS-01 Body Topical Supplement. It's definitely bougie, not inexpensive, but it has transformed the crepey skin of my body. Yes, it's expensive and yes, it's worth it, but you can just use it in targeted areas. I started out just using it over my knees last fall because that was kind of my area of concern, and then this spring I did a trial and used it on my crepey upper arms and my lower legs, but I skipped the torso. So it can be used just in trouble spots."

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"Two new body products I've been trying late this fall are the OneSkin OS-01 body lotion and the Fenty Skin whipped body butter, these in combination are just amazing. The OS-01 peptide in this body lotion penetrates the skin and helps renew it from the inside out. OneSkin is having an amazing bundle deal for only $99."

Allie Glines

830k subs

✓Approved

"I'm floored by the OneSkin OS-01 body supplement. It's an investment and packed with peptides, meant to tackle crepiness and repair the skin. Postpartum my stomach skin felt crepey, and even though they say wait six weeks, in the first few uses my skin already felt more bouncy and the crepiness was disappearing. I keep seeing results so I'm not going to stop."

Frequently asked.

What is OneSkin OS-01 Body Topical Supplement?

OneSkin OS-01 Body Topical Supplement is a peptide-based body treatment designed to address crepiness, support skin renewal, and improve the appearance of aging skin on the body.

Is OneSkin OS-01 Body Topical Supplement worth it?

Yes. All 5 gurus who reviewed it give it their stamp of approval, for a Guru Score of 86%.

What is OneSkin OS-01 Body Topical Supplement's Guru Score?

OneSkin OS-01 Body Topical Supplement holds a Guru Score of 86%. That is our read on how warmly the experts talk about it, based on the verdicts of 5 independent expert reviewers we have collected.