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One Skin

Peptide Moisturizer.

One Skin Peptide Moisturizer
Serums

About this product

A moisturizer containing a proprietary OS1 peptide designed to help clear senescent cells and support collagen production.

Best for

Mature skin
Serums

The Guru Index verdict

85%

Approved

✓Approved · 85%
4Reviewers
4Approved
0Mixed
0Skip

What the gurus are saying

Gurus consistently praise the OS1 peptide's mechanism for targeting damaged cells and stimulating collagen production, backed by clinical research from the founder PhDs. The recurring strength is its versatility as both a face and body moisturizer that layers well with active ingredients. The main hesitation is the premium price point, though experts view it as justified by the evidence supporting the peptide's efficacy.
Synthesized from 4 expert reviews

Where to buy

Every take, in full

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Approved only Skip only Mixed only Hide sponsored
Darnell Cox | 50+ Healthy Aging Expert
Darnell Cox | 50+ Healthy Aging Expert
54k subs · 616 devotees
✓Approved
"This is One Skin, which is an OS1 peptide. I did a whole show on peptides and how they're kind of like the text messengers of our body. They tell us what to do. This OS1 peptide really kind of helps to eliminate senescent cells, which are those zombie cells that create oxidative stress. So it helps to, it's not like it exfoliates, but it helps to rid your skin of those damaged cells, which then continues to damage the skin cells around it. So it's great in protecting that skin barrier, and it's great on top of an already active ingredient. I would argue that this is an active ingredient. It's a great way to spread out that product of a retinoid."
All 5 takes from Darnell Cox | 50+ Healthy Aging Expert
What's in my Travel Bag?
"I love this one skin i'm it has changed my skin barrier"
At-Home Body Treatments
"This is One Skin, which is an OS1 peptide. I did a whole show on peptides and how they're kind of like the text messengers of our body. They tell us what to do. This OS1 peptide really kind of helps to eliminate senescent cells, which are those zombie cells that create oxidative stress. So it helps to, it's not like it exfoliates, but it helps to rid your skin of those damaged cells, which then continues to damage the skin cells around it. So it's great in protecting that skin barrier, and it's great on top of an already active ingredient. I would argue that this is an active ingredient. It's a great way to spread out that product of a retinoid."
All of your pressing questions answered in today’s Instagram live show!
"I'm obsessed with this brand um one skin because they're really the way that it's working I swear it's repaired My Skin Barrier on my neck"
All of your pressing questions answered in today’s Instagram live show!
"I'm obsessed with this brand um one skin because they're really the way that it's working I swear it's repaired My Skin Barrier on my neck um but it's a moisturizer and yes it's a peptide"
Want younger-looking hands?🙌🏻 🎙️Tune into my IG Live Show where I’ll be Microneedling while
"I'm loving loving one skin um as a moisturizer for my hands"
Dr. Daniel Sugai
Dr. Daniel Sugai
716k subs · 23k devotees
✓Approved
"One Skin has great peptides that they were able to show me data, the evidence behind it that they work really well in the skin. Peptide moisturizers are great to add on to your routine, especially after a retinoid to help decrease irritation, but also boost your collagen, especially in your 30s as we start to lose collagen pretty fast. These cell signalers will tell your skin make more collagen."
All 4 takes from Dr. Daniel Sugai
Dermatologist Explains: How to Treat Neck Wrinkles and Tech Lines
"I like products with peptides. One Skin has a proprietary OS1 peptide that helps clear out the old cells that don't regenerate and it helps reverse biological age. It's a little bit more pricey, but I like that there's evidence behind this. One Skin was founded by PhDs and they do have papers that support their peptide that pretty much tell your skin cells to make more collagen, which is great, and it clears out the bad, the old cells."
Skincare Secrets to Manage Crepey Skin from a Dermatologist
"One Skin being a nice one with the OS1 peptide that has been shown to clear out the old non-regenerating cells out and helps stimulate collagen production. Those peptides will be a cell signal to tell your skin to make more collagen which is excellent. You can use that as a body moisturizer and you can use that over say your hyaluronic acid and that will help temporarily occlude the skin whereas your peptide moisturizers will hopefully give you long-term benefits right like retinol or vitamin C."
Dermatologist Explains: Anti-Aging Skincare Routine By Age
"I love that the PhDs that founded the company have sent me studies. I was able to look through the studies and I I like the products and so I I use their sunscreen and their moisturizers quite a bit."
Overhyped Skincare Ingredients for Collagen Boosting- Dermatologist Reviews
"One Skin has great peptides that they were able to show me data, the evidence behind it that they work really well in the skin. Peptide moisturizers are great to add on to your routine, especially after a retinoid to help decrease irritation, but also boost your collagen, especially in your 30s as we start to lose collagen pretty fast. These cell signalers will tell your skin make more collagen."
Beyond50Skin
Beyond50Skin
31k subs · 1k devotees
✓Approved
"Both formulas have their os1 peptide that's supposed to help compat ccent cells or our aging dying cells so I really like the formulas they're super hydrating"
All 2 takes from Beyond50Skin
Get RID OF SUN SPOTS (New Fall Anti-Aging OVER 50 Skincare Routine)
"So after I do my deete I put on moisturizer from brow to deete and I'm using the one skin moisturizer"
Thin Deflated LIPS OVER 50? Do This Now!
"Both formulas have their os1 peptide that's supposed to help compat ccent cells or our aging dying cells so I really like the formulas they're super hydrating"
Allie Glines
Allie Glines
830k subs · 34k devotees
✓Approved
"I also have um a new peptide moisturizer from one skin"
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