Obagi.

"Obagi uses hydroquinone and was revolutionary the first time, one of the first professional protocols for hyperpigmentation. However, it was done mainly on Caucasian skin and then exported to the rest of the world. For decades, this was the gold standard for pigmentation. Yet, hydroquinone is cytotoxic. It kills the cell, the melanocyte. While it works fast, it can cause a halo hyperpigmentation effect, white rings around the spots. And if used long term, it causes rebound effect where the pigmentation comes back aggressively once you stop. Not only does it come back, it tends to come back worse and tends to sprout on other parts of the face. It forces a cell into submission rather than regulating it."

"Health Dr Obagi always recommended a pretty aggressive approach to skin care. He recommended using tretinoin or Retin-A at the highest strengths, he recommended using prescription strength hydroquinone and aggressive physical exfoliators. If you get on the original Obagi formulas you can get dry flaking red inflamed skin, skin that literally looks like you are erupting, and that can persist for a couple of months. But the interesting thing with Obagi and his recommendations is you give it a few months of this skin that's just literally peeling off your face and red and irritated and it can really aggressively reverse the aging process. For people who have really sun damaged thick age skin being aggressive with skin care can create some very impressive results. But the problem is this type of aggressive skin care may be good if you've got really aged sun damaged skin but it can be actually not so good if you've got skin that already looks pretty good or if you've got skin that's sensitive or if you have dry skin. If you've got thin skin then by being really aggressive you can actually cause damage to your skin."