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NIOD

Copper Amino Isolate Serum 2:1.

NIOD Copper Amino Isolate Serum 2:1
Serums

About this product

A copper peptide serum designed to firm and rejuvenate skin.

Guru Score

73%

Mixed

9 experts · Strong agreement
9Gurus
5Yay
3Mixed
1Nay

What they liked

  • Lightweight, watery texture
  • Works well with non-retinoid routines
  • Firming and rejuvenating effects

What they flagged

  • Too thin for dry skin
  • Expensive compared to alternatives

What the gurus are saying

Its ultra-light, watery texture delivers visible firming and a more youthful appearance, a quality that sets this copper peptide serum apart from heavier alternatives. However, anyone with dry skin may find it too insubstantial, and some gurus note the price feels steep now that copper peptides are widely available at lower costs.
Synthesized from 9 expert reviews · most recent take August 2026

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored
~Yay
"The NIOD Copper Amino Isolate is amazing, I love this product a lot. Copper peptides stimulate collagen and firm the skin, and help address fine lines and premature signs of aging. I've been using copper peptides for several years now and it's all I use now because it really does perform, and I refuse to remove it from my routine."
Top Pick: copper peptide serum
All 13 takes from Sincerely Miss Ash
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"This is a copper peptide serum that I talk about all the time here on my channel and it's one of the best in my opinion. I do like to occasionally use this in my morning routine and sometimes at night time and I do like to alternate between this and other copper peptide serums as well."
8 HOLY GRAIL ANTI-AGING SKINCARE PRODUCTS I'D PAY DOUBLE FOR | THEY REALLY ARE THAT GOOD!
"This is a product that I've been using for several years. It's a holy grail. You guys see this in my empties videos all the time. And when there's a sale, I am stocking up on this. This is honestly one of the best copper peptide serums I have ever used. I really love this one because it is more advanced. I see quicker results with this serum. And this serum truly performs in terms of firming and just giving more of that rejuvenated youthful appearance to the skin. Copper peptides can also help to stimulate new collagen and softens fine lines and wrinkles and a great preventative serum as well. Now, this isn't a cheap serum. This is quite pricey. So when there is a sale, I generally like to stock up and purchase several bottles if I can. There are two sizes. This is a 30 mil size and then there is a 15 mil size which won't get you too far if you are using it every day, but it's a great size to purchase to see if you would like it. And then if you do then you can always move up to the 30 mil size. But I really love how this performs and this is honestly no joke. It is a serum that actually works."
BEAUTY EMPTIES 2023! SKINCARE, HAIRCARE & MAKEUP | PRODUCT'S I'VE USED UP SINCERELY MISS ASH
"I do have an empty NIOD Copper Amino Isolate Serum 2:1, this is the little 15 mil size. This is their copper peptide version which is very similar to The Ordinary one but I do feel like this one works a little bit better. The texture of this is like water whereas The Ordinary is more of that jelly type of texture, that gel. So it just depends on what preference you like in terms of texture and price point. This one is more money than The Ordinary but it's amazing and fabulous."
4 AMAZING COPPER PEPTIDE PAIRINGS FOR MAXIMUM RESULTS | ANTI-AGING, FIRMER SKIN, AND MORE!
"I also quite enjoy the NIOD Copper Amino Isolate Serum 2:1. Like, there's a lot that I do like."
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"NIOD also has one, it's the Copper Amino Isolate Serum, that one is very similar to The Ordinary, a little bit different in terms of ingredients and texture. I love that one as well but this one is a little bit more affordable."
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"I also love the NIOD Copper Amino Isolate Serum 2:1."
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"This is one of my favorite copper peptide serums, and this really performs. This firms the skin. It helps to stimulate collagen and it also helps to target fine lines and wrinkles. A very hydrating formula as well. It's very thin like water. It has a dark blue hue to it. And this is something that can be used in your morning as well as your evening skincare routine. When it comes to copper peptides, there are some products that you shouldn't pair up with it like direct acids, glycolic, lactic acid, salicylic acid. They also don't recommend to use retinol, retinaldehyde with this. Although I know that there are several people that do pair up the two together. But for me personally, I never pair this up with retinol. I keep it separate. So sometimes I will use this in my morning, retinol at night or if I'm taking a break from retinol in my evening routine then I will replace it with copper peptides. This always needs to be in my skincare routine some way somehow. Copper peptides truly take your skin to the next level when you compare it to regular peptide serums. So if you're using a regular peptide right now and you're not really seeing a difference with your skin, use copper peptides. And this one from NIOD is really advanced and I find it works pretty quickly. You have to be consistent."
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"The Neod brand is more advanced, which is why the prices are more expensive than the ordinary. It's one of my most repurchased serums as well. And I will alternate between the ordinary and this. Sometimes I use the ordinary copper peptides more just because it's more affordable, but this one at the end of the day performs better and quicker from my experience with it. The texture of this is like water. It's very thin. It's dark blue in color. It's very thin and lightweight. It dries down skin-like. There's no glow to your skin, and it's not sticky or tacky. It never pills with skincare, at least from my experience with this. And this can be used every day, twice a day. When I use this, I don't pair this up with other active ingredients like retinol, [tretinoin]. I don't pair this up with any type of exfoliating acid or ascorbic acid, vitamin C. You can use vitamin C derivatives with this. You can use growth factors with this. Niacinamide, hyaluronic acid. There's a lot of things you can use with copper peptides, but don't be using your other actives because you want to achieve maximum results with your copper. So, let this be the star of the show in your skincare routine. And then just pair up other hydrating and repairing products or growth factors for that matter. Growth factors pair up really well with copper peptides and peptides. So, you'll see a really great improvement with your skin."
BEAUTY EMPTIES 2023 | PRODUCT'S I'VE USED UP.. WILL I REPURCHASE?
"I have an empty Copper Amino Isolate Serum, so this is their copper peptide and this is very similar to The Ordinary Buffet plus copper peptides 1%. The serum that I shared with you is the old packaging but the formula is the exact same. This one is very similar to The Ordinary but they do contain different ingredients and the texture of this is more like water whereas the one from The Ordinary is more like a jelly. The one from The Ordinary I do feel like is a little bit more moisturizing on the skin but they both spread nicely across the skin. There's no paling whatsoever and I do feel like the NIOD one works a little bit quicker from the experience that I have had with the two but you can't go wrong with either one. So yes I will be continuing on with this for sure."
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"The ingredient list here is very impressive and I haven't found anything that is similar to this yet. I haven't found a dupe to this yet, so this truly is one of a kind in my opinion and it really is effective. It has a thinner texture, it's almost like water, but the formulation itself is more advanced."
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"This serum with that copper ingredient, I do feel like this one performs better. I achieved quicker results with this serum over the ordinary one, but of course we're all different and you can't go wrong with either one, they are both fabulous. So I'm going to rate this serum a 10 out of 10."
9 BEAUTY PRODUCTS THAT ARE ACTUALLY WORTH SAVING UP FOR
"NIOD Copper Peptide Aminoate is one of my top performing serums that I love using on a weekly basis, sometimes every day. Although I have a lot of favorites when it comes to copper peptides, this is my top pick, the one I've been using the longest and will always continue to use. It is truly 10 out of 10, this performs really well. I love how thin and lightweight it is, it's truly like water. Copper peptides help stimulate collagen, firm the skin and soften fine lines, and I think this one from NIOD is one of the most advanced formulations I've ever used. I saw results pretty quickly in terms of firming the skin when I was consistent with it, and even after trying other copper peptide serums I always go back to this one because it performs, and it performs really quickly. This is definitely worth the money in my opinion."
8 POWERFUL SKINCARE PAIRINGS THAT CAN ACTUALLY IMPROVE SIGNS OF AGING FASTER!
"The NIOD Copper Amino Isolate is amazing, I love this product a lot. Copper peptides stimulate collagen and firm the skin, and help address fine lines and premature signs of aging. I've been using copper peptides for several years now and it's all I use now because it really does perform, and I refuse to remove it from my routine."
~Yay
"The NIOD copper peptide products are ones I really like for incorporating copper peptides."
~Yay
"Their node copper serum is nice. It's super light, watery texture. So if for some reason their lipid serum is too heavy or you don't like the ordinary one, this one's nice. It's watery, so you can just add it into your routine pretty easily without having to change anything else. It's just super waterlike texture. So if you think the other one's too heavy, this one's nice. But it's expensive."
~Mixed
"It's not a holy grail mustave but yeah if you don't know the backstory you need to watch the backstory"
~Nay
"NIOD's copper peptide serum is extremely watery, too lightweight to really help you out if you have dry skin. I wouldn't buy this or their other copper peptide product again."
~Mixed
"The NIOD copper peptides are nice but too expensive. Copper peptides used to be unique and commanded a higher price point, but they do not anymore and do not need to."
~Yay
"On the non-retinoid nights I go in with the NIOD Copper Amino Isolate Serum 2:1. This is one of the more expensive versions, The Ordinary has a more affordable one, but I much prefer this texture, which is light, watery and not as oily as the other ones."
~Mixed
"I picked up the copper amino peptides. I've been trying copper peptides this year to see if I'm missing the boat on copper peptides and see how they respond on my mature skin. In the past I haven't thought they've worked but I'm game for trying them again. This was in my evening routine to kind of help with the hydration."
~Yay
"The copper peptides from NIOD are so fun. You get to mix them and activate them together. You should use them within 30 to 60 days, so if I'm buying this, if I'm mixing it end of November, I'm probably going to use it during December."

Frequently asked.

What is NIOD Copper Amino Isolate Serum 2:1?

A copper peptide serum designed to firm and rejuvenate skin.

Is NIOD Copper Amino Isolate Serum 2:1 worth it?

The gurus mostly approve it, but with enough reservations to keep it in the middle at a Guru Score of 73%.

What is NIOD Copper Amino Isolate Serum 2:1's Guru Score?

NIOD Copper Amino Isolate Serum 2:1 holds a Guru Score of 73%. That is our read on how warmly the experts talk about it, based on the verdicts of 9 expert reviewers we have collected. At least one expert has named it a Top Pick in its category.

Who is NIOD Copper Amino Isolate Serum 2:1 best for?

NIOD Copper Amino Isolate Serum 2:1 is generally suited to mature skin.

Cheaper alternatives the gurus rate.

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