Lancôme

Lancôme Rénergie H.P.N. 300 Peptide Cream.

Serums

About this product

A rich moisturizing cream formulated with peptides and niacinamide, designed to support mature and dry skin with a luxurious, cushioned texture.

Full ingredients

Aqua/Water, Glycerin, Dimethicone, Cetearyl Alcohol, Theobroma Grandiflorum Seed Butter, Alcohol Denat, Cetearyl Isononanoate, Niacinamide, Glyceryl Stearate, PEG-100 Stearate, Isopropyl Palmitate, Octyldodecanol, Cyclodextrin, Hydrolyzed Lupine Protein, Pisum Sativum Extract/Pea Extract, Adenosine, Capryloyl Salicylic Acid, Hydrolyzed Hyaluronic Acid, Hydrolyzed Linseed Extract, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Trisodium Ethylenediamine Disuccinate, Tocopheryl Acetate, Cera Alba / Beeswax, Orbignya Oleifera Seed Oil, Simmondsia Chinensis Butter/Jojoba Butter, Cetearyl Glucoside, Citric Acid, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polysorbate 60, Potassium Cetyl Phosphate, Sorbitan Isostearate, Tocopherol, Dimethicone/Polyglycerin-3 Crosspolymer, Benzyl Alcohol, Geraniol, Limonene, Chlorphenesin, Dipropylene Glycol, Phenoxyethanol

Guru Score

69%

Mixed

Early verdict · Few reviews so far

What they liked

Rich, cushiony texture
Peptides and niacinamide for skin support
Luxurious feel going on

What they flagged

Pricey for ingredients found in cheaper creams

What the gurus are saying

This cream delivers a genuinely luxurious feel and texture that many appreciate, especially those with dry or mature skin, thanks to its peptide and niacinamide blend. However, the same active ingredients show up in much more affordable formulas, so the premium price tag is largely for the experience and texture rather than performance that justifies the cost on paper alone. It's a lovely moisturizer if the indulgence factor matters to you, but not a must-have at this price point.

Synthesized from 2 expert reviews · most recent take September 2026

Best for

Dry skin Mature skin

Type

SerumsCream

Key actives

Niacinamide Hyaluronic acid Salicylic acid (BHA)Vitamin E

Formula notes

Contains drying alcohol

Where to buy

Sephora → Ulta → Amazon → Google →

Opens a store search. We may earn from these links.

Scan it in the shopFree iPhone app. Scores in the aisle.

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored

Dr. Aleksandra Brown

151k subs

~Mixed

"It's built around peptides and niacinamide which are all ingredients I actually like for supporting the skin over time. It's a lovely moisturizer. My only note here is really the price because niacinamide and peptides show up in much more affordable creams too. So do you really have to spend all that money on it? I don't know. You're really paying that premium for the texture and honestly the experience. And if that's what brings you joy in life, then it's completely valid."

Mixed Makeup

1.46M subs

~Mixed

"I love peptides in my skincare routine. [...] I enjoyed using this, I didn't love using this. I think I expected a lot from it. I didn't love the texture of it. [...] It wasn't super super super moisturizing for my dry skin, so I didn't end up feeling like this was the best because I still had to put moisturizer on top of it. I have dry skin though, so for somebody that doesn't have dry skin, maybe if you have normal skin you might find that this is moisturizing enough."

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Niacinamide

Niacinamide has evidence behind it for redness, uneven tone and supporting the skin barrier, and it is usually well tolerated even by skin that reacts to most things.

Source: DermNet

Salicylic acid

Salicylic acid dissolves in oil, so it can get into a pore rather than just working on the surface. That is why it has long-standing evidence for blackheads and milder acne.

Source: DermNet

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

Frequently asked.

What is Lancôme Rénergie H.P.N. 300 Peptide Cream?

A rich moisturizing cream formulated with peptides and niacinamide, designed to support mature and dry skin with a luxurious, cushioned texture.

Is Lancôme Rénergie H.P.N. 300 Peptide Cream worth it?

The gurus mostly approve it, but with enough reservations to keep it in the middle at a Guru Score of 69%.

What is Lancôme Rénergie H.P.N. 300 Peptide Cream's Guru Score?

Lancôme Rénergie H.P.N. 300 Peptide Cream holds a Guru Score of 69%. That is our read on how warmly the experts talk about it, based on the verdicts of 2 expert reviewers we have collected.