Index / La Roche-Posay / Melasyl B3 Serum

La Roche-Posay Melasyl B3 Serum.

Serums

About this product

A La Roche-Posay serum built around the Melasyl ingredient and niacinamide (vitamin B3), designed to target dark spots and uneven skin tone.

Guru Score

61%

Mixed

Early verdict · Few reviews so far

What the gurus are saying

Melasyl looks great in the research, yet the takes split on whether it shows up on real skin. Some saw no results at all, even with samples and full sizes, and say skip it for now. Others say it can work if you tolerate it, perhaps twice a day, and since the brand's sunscreen has it too, sunscreen by day with serum at night is reasonable.

Synthesized from 2 expert reviews · most recent take October 2026

Type

Serums

Where to buy

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What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

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Dr. Daniel Sugai

723k subs

~Nay

"I was really excited about the new Melasyl ingredient, and the research results look great. But when I and my patients tried it, including samples and full sizes, we saw no results. I was very disappointed by the real-world results, so I would say skip it for now."

Dr Dray

2.69M subs

~Mixed

"I really do think that the serum if you can tolerate it will get you results to you know better perhaps if used twice a day that being said the sunscreen has micil in it so if you use a sunscreen in the morning and the serum at night I think that's also reasonable to do"

Frequently asked.

What is La Roche-Posay Melasyl B3 Serum?

A La Roche-Posay serum built around the Melasyl ingredient and niacinamide (vitamin B3), designed to target dark spots and uneven skin tone.

Is La Roche-Posay Melasyl B3 Serum worth it?

The gurus mostly approve it, but with enough reservations to keep it in the middle at a Guru Score of 61%.

What is La Roche-Posay Melasyl B3 Serum's Guru Score?

La Roche-Posay Melasyl B3 Serum holds a Guru Score of 61%. That is our read on how warmly the experts talk about it, based on the verdicts of 2 expert reviewers we have collected.