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La Roche-Posay Hyalu B5 Serum.

La Roche-Posay Hyalu B5 Serum
Serums
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About this product

A hydrating serum combining hyaluronic acid and panthenol (vitamin B5) designed to plump skin and support the skin barrier by drawing moisture into the complexion.

Full ingredients

Guru Score

79%

Yay

5 experts · Moderate agreement
5Gurus
4Yay
1Mixed
0Nay

What they liked

  • Instant plumping effect
  • Draws moisture into skin
  • Fragrance has a nostalgic scent

What they flagged

  • Fragrance may irritate sensitive skin
  • Needs a moisturiser or occlusive on top

What the gurus are saying

The serum's plumping effect earns consistent praise, with dermatologists noting how effectively the hyaluronic acid draws water into skin for an instant, visible boost in firmness and dewiness. The formula also carries panthenol for barrier support, and works especially well around the eyes and on damp skin layered under a moisturizer to lock in hydration. One caveat: it contains fragrance, which may not suit anyone with a true fragrance sensitivity, though dermatologists who tested it found the scent pleasant and nostalgic.
Synthesized from 5 expert reviews · most recent take March 2026

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored
✓Yay
"If you want more of a plumping action, I love the La Roche-Posay Hyalu B5. But it does have fragrance. For me, I love the fragrance. It smells very nostalgic to me."
Top Pick: hyaluronic acid serum
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"If you want more of a plumping action, I love the La Roche-Posay Hyalu B5. But it does have fragrance. For me, I love the fragrance. It smells very nostalgic to me."
How to Fix Dehydrated Skin: Best Hydrating Products of the Year
"It's their Hyalu B5. I remember first using this in 2020 when I was introduced to a lot more skin care than I usually am exposed to as a medical dermatologist. And so when I first used this, I loved how plumping it was. It really draws in water, causes that instant plumping effect. It does have a little bit of a scent and fragrance, and I like it. It actually is very nostalgic to me."
Dermatologist Reviews: Essentials in your Winter Skincare Routine!
"La Roche-Posay has a Hyalu B5, one of my favorites. [...] Hyaluronic acid [...] is a water magnet. Put that on damp skin after you cleanse to trap in all that moisture, and then go ahead and put a moisturizing cream over it."
Dermatologist Explains: Three Ways to Improve Crow’s Feet!
"After you cleanse in the morning while your skin's damp or if you're not washing your face you want to spray yourself down with some thermal spring water on your face and hydrate your skin. You want to put a hydrator like hyaluronic acid, my favorite being La Roche-Posay Hyalu B5."
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"This one is the La Roche-Posay Hyalu B5. One of my favorite all-time products from them. Hyaluronic acid is a nice carbohydrate that will draw in water, plump up the skin. So while your skin's damp, go ahead and apply a few drops of this to your face. And what I love about this is that it is very plumping. One of the easiest ways to hide fine lines and wrinkles is to apply hyaluronic acid serum followed by a moisturizer to seal that in."
Skin Hydration 101: Tips From A Dermatologist For Hydrated, Plump Skin
"I've been using this one more than the regular Vichy Mineral 89. My favorite all-time hyaluronic acid serum that has this fragrance that just brings me back to when I first started social media in 2020. When I smell that La Roche-Posay Hyalu B5 I'm just always brought back to the start of social media and it's a great hydrator, it's a great plumper. I think it plumps my skin better than the Vichy Mineral 89 but if you don't like fragrance then go with Vichy for sure."
Dermatologist Explains: Top Beauty Secrets (and Can Exercise Help with Wrinkles?)
"If you wanted to check out La Roche-Posay Hyalu B5 Serum, my patient today came in and said oh my gosh I saw your video I picked up that Hyalu B5 and it's awesome. She loves it. She's tried many different hyaluronic acid serums and that one for her big winner picks up all that moisture. Then layer over it with a moisturizer or a moisturizer with SPF. It's a nice boost of hydration and glowy texture before a big event, say going on the news or going to a holiday party, going to a reunion."
Dermatologist Explains: Three Skincare Hacks You Need to Do Now!
"If you have L POS how B5 or this on damp skin it's really going to draw in that water"
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"I've been using this one more than the regular Vichy Mineral 89. My favorite all-time hyaluronic acid serum that has this fragrance that just brings me back to when I first started social media in 2020. When I smell that La Roche-Posay Hyalu B5 I'm just always brought back to the start of social media and it's a great hydrator, it's a great plumper. I think it plumps my skin better than the Vichy Mineral 89 but if you don't like fragrance then go with Vichy for sure."
Dermatologist Explains: Three Ways to Glow Up Your Skin Today
"My favorite though of all time would have to be the Hyalu B5 by La Roche-Posay. That one is fragrant but I love the smell. I love how hydrating it is. I feel like it plumps my skin up better than even Vichy. You got to check that one out if you haven't yet. But if you are allergic to fragrance, if you have a known allergy to fragrance, then probably not for you."
Dermatologist Reviews: Holiday Skincare Picks for All Ages 2023
"My favorite still though has to be La Roche-Posay Hyalu B5 Serum still my favorite Hyalu B5 man it's just packed with hyaluronic acid that's a water sponge that draws in water and it just keeps it all there and it really plumps up my skin it feels so great and if you have a big event and you want to have a little plump dewy look use that it does have fragrance though so it has this familiar smell that I'm totally okay with and I love that smell so familiar works well on my skin but if you have a true fragrance allergy then maybe not for you"
✓Yay
"This serum combines hyaluronic acid with vitamin B5 which is a soothing ingredient that helps repair the skin barrier. It's particularly effective for sensitive skin as it's hydrating without any irritation. The key ingredients here are the hyaluronic acid, vitamin B5, and niacinamide. Hyaluronic acid has nothing to do with actual acids. It's a misnomer in my opinion because a lot of people think it's going to be irritating because it has the acid. It's really a completely hydrating serum."
All 5 takes from Dr. Aleksandra Brown
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"I really like the La Roche-Posay Hyalu B5 or even the V2 mineral 89. You want to apply it directly to damp lips. You don't want to put it on completely dry lips, okay? Because hyaluronic acid by itself doesn't really moisturize. It pulls the moisture. So you want to make sure that you're one drinking lots of water, two your lips are just a little bit damp and then you apply your hyaluronic acid and immediately after applying that hyaluronic acid you want to put your occlusive on."
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"This serum combines hyaluronic acid with vitamin B5 which is a soothing ingredient that helps repair the skin barrier. It's particularly effective for sensitive skin as it's hydrating without any irritation. The key ingredients here are the hyaluronic acid, vitamin B5, and niacinamide. Hyaluronic acid has nothing to do with actual acids. It's a misnomer in my opinion because a lot of people think it's going to be irritating because it has the acid. It's really a completely hydrating serum."
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"This one's just like the Vichy because you want to apply it to damp skin. It will help plump the skin. This one also has a little bit of vitamin B5. It's really soothing ingredient that's going to help repair the barrier. It has a little bit of a scent, but it's really soothing, really nice. It provides that immediate sustained hydration and it's really good if you have sensitive skin and if you're really really dry."
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"I find it a little bit more hydrating than the L'Oreal one. It also helps target those fine lines and dullness really just by replenishing the moisture. It has a little bit thicker texture but absorbs really quick. It sits really well under your moisturizer or underneath the SPF. Just like with the other one, I like to put moisturizer right on top. The key ingredients are vitamin B5 or panthenol, hyaluronic acid, and niacinamide."
Dermatologist’s Guide to Choosing the Right Serum for Your Skin
"It's particularly effective for sensitive skin as it's hydrating without any irritation. Some of the key ingredients are things like hyaluronic acid, which helps draw moisture to the skin for a plump, hydrated complexion. It also contains vitamin B5, known for its calming and healing properties, and it works to improve skin resilience and barrier function. It also contains Madecassoside, which is derived from Centella asiatica."
✓Mixed
"Some people really love the texture of this, but for me I would say if there's anything negative to say about the serum is that it does for me at least feel a little bit sticky and tacky after it's fully absorbed. The other thing too is it is fragrance, and that's the other thing if people who have sensitive skin or at least sensitive to fragrance this serum may not be the best."
✓Yay
"When I was using that around my eyes, man, it really had a drastic effect in tightening the skin on my eyes. [...] That is a great skin protectant for around your eyes for reducing eyelid irritation. If you're dealing with aerosolized allergens, pollen, molds, or cooking spices that settle on the eyelids, it can help prevent eyelid dermatitis [...] and heal it as well. It's glycerin based, so in contrast to other balms, it is a lot more hydrating and it doesn't go on opaque white."
All 2 takes from Dr Dray
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"When I was using that around my eyes, man, it really had a drastic effect in tightening the skin on my eyes. [...] That is a great skin protectant for around your eyes for reducing eyelid irritation. If you're dealing with aerosolized allergens, pollen, molds, or cooking spices that settle on the eyelids, it can help prevent eyelid dermatitis [...] and heal it as well. It's glycerin based, so in contrast to other balms, it is a lot more hydrating and it doesn't go on opaque white."
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"The La Roche-Posay Hyalu B5 is scented, and I've never really found it to be particularly wonderful."
✓Yay
"I have a list of some of my favorite hydrating serums like the La Roche-Posay Hyalu B5 hyaluronic acid serum"

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

Vitamin E

Vitamin E is an antioxidant, and it is often in a formula to keep the other ingredients stable rather than as the active itself. It pairs well with vitamin C, though on its own the evidence for visible change is limited.

Source: NIH, National Library of Medicine

Frequently asked.

What is La Roche-Posay Hyalu B5 Serum?

A hydrating serum combining hyaluronic acid and panthenol (vitamin B5) designed to plump skin and support the skin barrier by drawing moisture into the complexion.

Is La Roche-Posay Hyalu B5 Serum worth it?

Mostly yes. 4 of the 5 gurus who reviewed it give it their stamp of approval, for a Guru Score of 79%.

What is La Roche-Posay Hyalu B5 Serum's Guru Score?

La Roche-Posay Hyalu B5 Serum holds a Guru Score of 79%. That is our read on how warmly the experts talk about it, based on the verdicts of 5 expert reviewers we have collected. At least one expert has named it a Top Pick in its category.

Who is La Roche-Posay Hyalu B5 Serum best for?

La Roche-Posay Hyalu B5 Serum is generally suited to dry skin and sensitive skin.

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