Index / Hyphen / Advanced Depigmentation Serum
Hyphen

Hyphen Advanced Depigmentation Serum.

About this product

A lightweight serum designed to reduce dark spots and hyperpigmentation, formulated with kojic acid, licorice extract, and other depigmenting actives.

Full ingredients

Purified Water, Ananas Sativus (Pineapple) Fruit Extract, Tranexamic Acid, Glycyrrhiza Glabra (Licorice) Root Extract, Kojic Acid, Phenoxyethanol, Sodium Hyaluronate, Melatonin, Aloe Barbadensis (Aloe Vera) Leaf Extract, Curcuma Longa Turmeric Root Extract, Hydroxyethylcellulose, D-Panthenol, Sodium Metabisulphite, Ethylhexylglycerin, Sodium Gluconate, Citric Acid

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Guru Score

69%

Mixed

Early verdict · Few reviews so far

What the gurus are saying

This serum earns praise for its thoughtful ingredients (licorice extract at an effective dose and heavy airless packaging) yet stability is a real problem. One reviewer found it oxidized and discolored within weeks, becoming irritating on skin, while another praised the formula itself as her favorite depigmentation serum tested so far but flagged that the kojic acid lacks stabilization. The texture and scent are pleasant, but anyone considering it may want to check the batch date carefully and patch-test first, since potency and irritation seem tied to how fresh the product is.
Synthesized from 2 expert reviews · most recent take July 2026

What they liked

  • Kojic acid and tranexamic acid combination
  • Dark glass packaging protects ingredients
  • Subtle fragrance

What they flagged

  • Unstabilized kojic acid
  • Degrades quickly once opened
  • Pineapple extract may irritate sensitive skin

Type

Key actives

Formula notes

Fragrance-freeNo drying alcohol

Where to buy

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What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored
~Yay
"I do like that they've added in licorice extract and it's in the therapeutic index, but they haven't stabilized the kojic acid, that's something I would say. I do like the heavy packaging, I think Hyphen has probably one of the best packaging in India. [...] The smell's actually not bad. This is probably my favorite depigmentation serum so far in what we've looked at."
~Nay
"This product goes bad so fast that I cannot tell you. I tried this product on my arms and certain places where I had acne marks last year for two weeks. When I wanted to reuse it, it had already gone bad. [...] I think this needs to be reformulated and my results in the first two weeks were not impressive honestly on this area because I felt the product was too strong and it was kind of irritating. Despite being an airless pump, it got completely discolored."

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Tranexamic acid

Tranexamic acid has a growing body of clinical evidence for melasma and the stubborn patches of pigment that other ingredients struggle with.

Source: DermNet

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

Frequently asked.

What is Hyphen Advanced Depigmentation Serum?

A lightweight serum designed to reduce dark spots and hyperpigmentation, formulated with kojic acid, licorice extract, and other depigmenting actives.

Is Hyphen Advanced Depigmentation Serum worth it?

The gurus mostly approve it, but with enough reservations to keep it in the middle at a Guru Score of 69%.

What is Hyphen Advanced Depigmentation Serum's Guru Score?

Hyphen Advanced Depigmentation Serum holds a Guru Score of 69%. That is our read on how warmly the experts talk about it, based on the verdicts of 2 expert reviewers we have collected.

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