Epiduo: a Guru Score of 77% from 6 skincare experts

Every take, in full

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

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✓Approved

"Epiduo is adapalene plus benzoyl peroxide combined into one cream instead of two separate products, and that's great for patients with acne because it's a lot easier to stick with one cream than to layer two different creams, so patients are more compliant with it. The combination of adapalene and benzoyl peroxide together can be particularly powerful for acne and can get better results than either alone in some cases, though not everyone needs the combination. If you're already using over-the-counter adapalene for anti-aging, I don't see any reason to switch to Epiduo, because the benzoyl peroxide won't offer any anti-aging benefit and is just more likely to be drying and irritating, plus you have to deal with it bleaching fabrics. But if you're dealing with post-inflammatory hyperpigmentation, the combination can help by getting better control of the acne driving it. Epiduo is also a very good option for ingrown hairs, which are common in the beard area, especially for men with curlier or coiled hair, since those ingrown hairs often turn into inflamed, acne-like bumps that heal with hyperpigmentation. I'm really elated that it's now available over-the-counter, because it simplifies things a lot compared to telling patients to go find their own benzoyl peroxide separately, where they're statistically more likely to accidentally grab the more drying and irritating 10 percent instead of the 2.5 percent."

All 3 takes from Dr Dray

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"Epiduo, if you're not familiar, is [adapalene] plus benzoyl peroxide. Yeah, you can use that indefinitely long term for the treatment of acne, which is what it's indicated for. There's no issue that has been established with long-term consistent use of either ingredient, [adapalene] or benzoyl peroxide. You don't need to take breaks in the summer or spring months. You don't need to take breaks for seasonal reasons from topicals. The topical retinoid, specifically [adapalene] in this case, it doesn't increase your chance of a sunburn. It's actually good for you to be using a topical retinoid in the sunnier months because it helps to protect collagen in your skin to a certain extent by limiting activation of matrix metalloproteinase enzymes that get upregulated with ultraviolet radiation that then destroy your collagen and facilitate wrinkles and premature skin aging. [Adapalene] also has this anti-inflammatory effect that can be beneficial as well."

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"The FDA has approved over-the-counter Epiduo, which combines adapalene and benzoyl peroxide. This is exciting because previously people who used both adapalene and benzoyl peroxide for acne treatment had to buy them separately and layer them together, but now they can get both ingredients in one product."

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"Epiduo is adapalene plus benzoyl peroxide combined into one cream instead of two separate products, and that's great for patients with acne because it's a lot easier to stick with one cream than to layer two different creams, so patients are more compliant with it. The combination of adapalene and benzoyl peroxide together can be particularly powerful for acne and can get better results than either alone in some cases, though not everyone needs the combination. If you're already using over-the-counter adapalene for anti-aging, I don't see any reason to switch to Epiduo, because the benzoyl peroxide won't offer any anti-aging benefit and is just more likely to be drying and irritating, plus you have to deal with it bleaching fabrics. But if you're dealing with post-inflammatory hyperpigmentation, the combination can help by getting better control of the acne driving it. Epiduo is also a very good option for ingrown hairs, which are common in the beard area, especially for men with curlier or coiled hair, since those ingrown hairs often turn into inflamed, acne-like bumps that heal with hyperpigmentation. I'm really elated that it's now available over-the-counter, because it simplifies things a lot compared to telling patients to go find their own benzoyl peroxide separately, where they're statistically more likely to accidentally grab the more drying and irritating 10 percent instead of the 2.5 percent."

208SkinDoc

2.08M subs

✓Approved

"Epiduo was just approved by the FDA for over-the-counter use. This has been prescription only for a long time. It is adapalene, which was also prescription, and then went over the counter. Adapalene or Differin is the brand name. They also make one called Epiduo, and it has benzoyl peroxide with the adapalene. So, a really good acne treatment just went over the counter."

Dr. Mamina

279k subs

✓Approved

"Epiduo is a combination of 0.1% adapalene and 2.5% benzoyl peroxide. FDA did approve the use of Epiduo in kids as young as the age of nine."

Lab Muffin Beauty Science

858k subs

✓Approved

"The stability from these rings also makes it really good for acne because it means you can layer it with benzoyl peroxide and you can also get it in a relatively simple combo formula which is called Epiduo."

Hyram

4.35M subs

✓Approved

"If home remedies and acne treatments aren't working, it's time to see the doctor and he prescribed me Epiduo and it actually works. Epiduo, oh my God, that is incredible."

Cassandra Bankson

2.45M subs

✓Approved

"There is a medication called Epiduo. Epiduo is literally adapalene, which is a form of retinoid, plus benzoyl peroxide, and it works really great for acne. It's a prescription. A doctor or provider might say, hey, we're going to custom blend a retinoid in with benzoyl peroxide to help you get the most out of your skin care. If prescribed by a doctor, go for it."

Common questions

Frequently asked.

What is Epiduo?

A prescription and over-the-counter acne treatment combining 0.1% adapalene (a retinoid) and 2.5% benzoyl peroxide in a single formula.

Is Epiduo worth it?

Yes. All 6 gurus who reviewed it give it their stamp of approval, for a Guru Score of 77%.

What is Epiduo's Guru Score?

Epiduo holds a Guru Score of 77%. That is our read on how warmly the experts talk about it, based on the verdicts of 6 independent expert reviewers we have collected.