Epiduo.

"Epiduo, if you're not familiar, is adapylene plus benzoyl peroxide. Yeah, you can use that indefinitely long term for the treatment of acne, which is what it's indicated for. There's no issue that has been established with long-term consistent use of either ingredient, adapylene or benzoyl peroxide. You don't need to take breaks in the summer or spring months. You don't need to take breaks for seasonal reasons from topicals. The topical retinoid, specifically adapylene in this case, it doesn't increase your chance of a sunburn. It's actually good for you to be using a topical retinoid in the sunnier months because it helps to protect collagen in your skin to a certain extent by limiting activation of matrix metalloproteinase enzymes that get upregulated with ultraviolet radiation that then destroy your collagen and facilitate wrinkles and premature skin aging. Adapylene also has this anti-inflammatory effect that can be beneficial as well."

"The FDA has approved over-the-counter Epiduo, which combines adapalene and benzoyl peroxide. This is exciting because previously people who used both adapalene and benzoyl peroxide for acne treatment had to buy them separately and layer them together, but now they can get both ingredients in one product."