Index / Eli Lilly / Mounjaro
Eli Lilly

Mounjaro.

Eli Lilly Mounjaro

About this product

Mounjaro is an injectable medication containing tirzepatide, a dual GLP-1 and GIP receptor agonist designed to help manage blood sugar levels and support weight management.

Type

Guru Score

65%

Mixed

Early verdict · Few reviews so far
2Gurus
1Approved
0Mixed
1Skip

What the gurus are saying

Tirzepatide works by mimicking two hormones that signal fullness to the brain and slow stomach emptying, keeping the hormone active in the body for about a week rather than minutes, so people feel satisfied longer during meals. One concern raised is that when stopping the medication, the slowed digestion may reverse, potentially triggering a rebound effect as the body readjusts to its normal pace.
Synthesized from 2 expert reviews · most recent take March 2025
Every take, in full

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Approved takes Critical takes Mixed takes Hide sponsored
~Approved
"The newest medication on the market is tirzepatide, so that's Mounjaro or Zepbound. There's a GLP1 agonist component and a GIP, so it has two hormones. These are basically synthetic hormones of GLP1 that have a component in it that prevents the breakdown of it, so the hormone GLP1 is around your body a lot longer. The half-life is about a week, so instead of you releasing this hormone and it being broken down in one to two minutes, the hormone is floating around for a lot longer. It sends signals to our brain where we have receptors and it says, 'Brain, I'm full,' even while you just started eating because it's already around in the body. It also slows down the rate at which the stomach empties, so if it takes a normal stomach four hours to empty, then the food in your stomach may stay in there for five or six hours. It usually delays that by about one hour."
~Skip
"When you're on semaglutide, which is the active ingredient in those weight loss shots, it's a GLP-1 agonist, right, so it makes you feel full. It slows down the pace at which your food travels through your digestive tract. Now if we just all put on our thinking caps for a second and thought about metabolism, there should be some bells going off that when you get off of this, that has slowed down your metabolism because it slowed down the way food moves through your body. You're going to have a rebound effect."
Common questions

Frequently asked.

What is Eli Lilly Mounjaro?

Mounjaro is an injectable medication containing tirzepatide, a dual GLP-1 and GIP receptor agonist designed to help manage blood sugar levels and support weight management.

Is Eli Lilly Mounjaro worth it?

The gurus mostly approve it, but with enough reservations to keep it in the middle at a Guru Score of 65%.

What is Eli Lilly Mounjaro's Guru Score?

Eli Lilly Mounjaro holds a Guru Score of 65%. That is our read on how warmly the experts talk about it, based on the verdicts of 2 independent expert reviewers we have collected.

You might also like

Similar products worth a look.

Other products the same gurus have weighed in on, plus more from this brand and category.

Compare side by side →

This week's top beauty news, in your inbox.

A weekly read of the takes worth catching up on: the raves, the splits, the ones the gurus won't shut up about. Free, no spam, unsubscribe whenever.

Subscribe to the digest