Index / DRMTLGY / Needleless Growth Factor Serum
DRMTLGY

Needleless Growth Factor Serum.

DRMTLGY Needleless Growth Factor Serum
Serums

About this product

A serum formulated with growth factors designed to support skin renewal and improve texture without needles or invasive procedures.

Best for

Mature skin
Serums

The Guru Index verdict

79%

Approved

Approved · 79%
5Reviewers
4Approved
0Mixed
1Skip

What the gurus are saying

Gurus largely praise this serum for its hydrating, plumping, and anti-aging benefits, with particular enthusiasm for its growth factor and peptide content. The recurring strength is that it delivers visible firmness and texture improvement at a lower price point than comparable products. A minority split finds it insufficiently hydrating or effective, with one reviewer seeing no meaningful difference in skin quality.
Synthesized from 5 expert reviews
Every take, in full

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Approved only Skip only Mixed only Hide sponsored
Approved
"This one is a bio-engineered, vegan, biotech powered growth factor serum that's designed to support firmness, texture, and overall skin quality without using any human derived growth factors. It's also clinically proven to outperform the leading human growth factor serum that retails for $295. By far, this is the cheapest option on the list. The key ingredients here are the five times biogrowth factor complex, this versa chirata extract and the palmatyl trapeptide. I am currently using this one and I like it a lot."
Top Pick: growth factor serum
Approved
"This is the dermatology needleless growth factor serum. It's a really nice serum from dermatology and it has multiple different peptides that act as growth factors in the skin. And that is able to stimulate your skin cells, fibroblast growth factor, platelet derived growth factors that can stimulate your collagen and elastin to build. It can speed up your skin cell turnover. If you're looking for growth factors, which I think are a little bit more advanced, meaning you've already mastered your retinoids and you've already mastered some of the more entry-level peptides like metatricxel or copper peptides and you haven't seen great results with them, I think growth factors are really the next step. I think the one from dermatology is a great option for somebody who is looking to introduce because it's not so expensive like the one from Allies of Skin."
Approved
"My favorite skin care item from Dermatology is the Needleless Growth Factor Serum. It's a really nice peptide serum."
Skip
"That is one product that just doesn't work for me. I personally just didn't see that much of a difference in my skin when I used it. And also, it just wasn't quite hydrating enough for me."
All 2 takes from Beyond50Skin
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"That is one product that just doesn't work for me. I personally just didn't see that much of a difference in my skin when I used it. And also, it just wasn't quite hydrating enough for me."
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"I've tried the Needleless Growth Factor Serum and I just didn't find the wild factor that so many of you love. It has niacinamide, it has copper peptides, it has ceramides, and it has hyaluronic acid. For a one-and-one serum, for many of you this could be the answer, but I have very very dry skin and this isn't quite hydrating enough. I also treat different skincare concerns in my treatment step in the morning than just hydration. This is a slightly firming and hydrating type serum, but I need something geared toward anti-pigmentation, soothing, and anti-redness. If you have normal to oily skin type and you are just looking for a bit of hydration, this could be the perfect serum for you, but for me personally I need something a little bit more hydrating."
Approved
"This is another one that you can use every day twice a day. There's a lot of other great ingredients in here to nourish, to hydrate. It does plump up the skin and it's also very hydrating. This is way better in my opinion than the original needleless serum. This has a milkiness to it, whereas the original needleless serum is more like water, but the original one does not have growth factors in it. So if you love growth factors and peptides, this formulation really is worth looking into. But this on its own is 10 out of 10. If you didn't want to pair this up with anything, then just pair this up with a moisturizer and a sunscreen if it's in your morning routine and away you go."
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All 5 takes from Sincerely Miss Ash
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"This is another one that you can use every day twice a day. There's a lot of other great ingredients in here to nourish, to hydrate. It does plump up the skin and it's also very hydrating. This is way better in my opinion than the original needleless serum. This has a milkiness to it, whereas the original needleless serum is more like water, but the original one does not have growth factors in it. So if you love growth factors and peptides, this formulation really is worth looking into. But this on its own is 10 out of 10. If you didn't want to pair this up with anything, then just pair this up with a moisturizer and a sunscreen if it's in your morning routine and away you go."
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"This is really nice and it's also very lightweight on the skin. There's no fragrance. Great for all skin types and this is 10 out of 10."
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"I am very impressed with this formulation. This contains five bioengineered growth factors. Growth factors help to stimulate collagen and it helps with fine lines and wrinkles. It firms the skin, but it also has the ability to heal your skin. So if you have sensitive skin, you have a compromised skin barrier, then this can be a great product to use to keep your skin healthy and repaired. But it's also very hydrating and I find this serum to be quite plumping as well. This really is so good."
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"The DRMTLGY Needleless Growth Factor Serum is probably one of Dermatology's most popular products. It's a great anti-aging serum to soften fine lines and wrinkles, to help firm the skin, to give fullness, and it's an amazing hydrating serum as well. This serum contains several types of ceramides which can help to repair and strengthen your skin barrier, there are peptides in here, there's niacinamide, hyaluronic acid, provitamin B5, and there is a copper ingredient in here as well. I've always seen great results with this. You can bring this down your neck and your chest as well. You can use this every day, twice a day if you wish to, and this is also a great serum to pair up with retinol or tretinoin."
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"This really is a lovely serum for signs of aging to firm the skin and also to hydrate the skin. This is a product that you can use every day twice a day and this is basically your peptide serum. It has a few different peptides but there's also a copper peptide complex in here which is another reason why I love this one so much because I am the biggest fan of copper peptides. I truly believe that this ingredient is really effective it does help to stimulate new collagen just like peptides do but with copper peptides I just feel like I see a bigger difference with my skin in terms of how it looks more firm. Besides the peptides here there is niacinamide and I am one of the biggest fans of this ingredient as it really does help to even out your skin tone and it's a great antioxidant that really helps to prevent transepidermal water loss so it does help to hydrate the skin. It's great for acne prone skin and for those that have oily skin but even if you have dry skin niacinamide can be wonderful to incorporate as it really does help to hydrate and prevent water loss."
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