Dr. Reju-All

Dr. Reju-All Advanced PDRN Rejuvenating Lip Serum.

Name: Dr. Reju-All Advanced PDRN Rejuvenating Lip Serum
Brand: Dr. Reju-All

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Lip

About this product

A lip serum featuring PDRN (polydeoxyribonucleotide) with liposomal, lipid-coated delivery designed to hydrate and support collagen in the lips.

Full ingredients

Polybutene, Pentaerythrityl Tetraethylhexanoate, Cetyl Ethylhexanoate, Hydrogenated Polyisobutene, Tribehenin, Microcrystalline Wax (Cera Microcristallina/Cire Microcristalline), Sorbitan Isostearate, VP/Hexadecene Copolymer, Silica Silylate, Allantoin, Water (Aqua/Eau), Glycyrrhetinic Acid, Tocopheryl Acetate, Butylene Glycol, Pyridoxine Hcl, Adenosine, Cetylpyridinium Chloride, Polyglyceryl-2 Oleate, Hibiscus Sabdariffa Flower Extract, Oryza Sativa (Rice) Bran Oil, Macadamia Ternifolia Seed Oil, Sodium Dna, Pyruvic Acid, Lactic Acid, Candida Bombicola/Glucose/Methyl Rapeseedate Ferment, Acetic Acid

Guru Score

Not verified

Score withheld

No independent takes

All 2 takes here are sponsored by the brand. With no independent take to weigh, there is not enough to publish a verified score. The takes are below, each labeled.

What they liked

Soft applicator that doesn't drag
Fragrance-free, gentle for sensitive lips
Long-lasting hydration

What they flagged

Very glossy finish

What the gurus are saying

The soft, cushioned applicator glides without dragging, though the formula sits glossy on lips until blotted. What sets this serum apart is its gentle formula, which passes even for people with sensitive lips and throats that typically sting from lip products. Gurus found it delivers lasting hydration and plumps the lips without irritation.

Synthesized from 2 expert reviews · most recent take September 2026

Best for

Mature skin

Type

LipDrops & dropper

Key actives

AHAVitamin E

Formula notes

Fragrance-freeNo drying alcohol

Where to buy

Ulta → Amazon → Google →

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What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored

Kelly Driscoll

90k subs

✓Yay

"I'm going to be using the Dr. Rejuvenated Advanced PDRN Rejuvenating Lip Serum. Keeping my lips hydrated, plump, and smooth is definitely a priority for me, and I really love the way that this serum delivers long lasting hydration for my lips."

Sponsored

All 2 takes from Kelly Driscoll

Why Your PDRN Product Might Not Be Working | AD ft. Dr. Reju-All

"This is genuinely the product I didn't know I needed. It's liposomal, lipid coated PDRN with reverse micelle delivery [...] engineered specifically for lip absorption, fragrance free and sensitive lip approved. I have such sensitive lips and throat that most lip products sting, burn or irritate the back of my throat, but this one is sensitive lip, sensitive throat, sensitive everything approved for me."

Everything I Put on My Face at 37 | Full Morning and Night Routine

Doctorly

3.59M subs

✓Yay

"The tip is soft but not grabby, so it's weird to have a cushiony, pillowy, rubbery applicator that also doesn't drag across the skin. [...] I will say though, the one knock on it is that it's very glossy. [...] I do kind of the guy thing, I put it on, wipe it off, and it's fine. [...] This applicator tip is insane, and it's got PDRN in it, which theoretically could help support collagen in the lips."

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Alpha hydroxy acids

Alpha hydroxy acids loosen the bonds holding dead cells at the surface. The evidence supports smoother texture and more even tone over time, and they can leave skin more sensitive to sun.

Source: NIH, National Library of Medicine

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

Vitamin E

Vitamin E is an antioxidant, and it is often in a formula to keep the other ingredients stable rather than as the active itself. It pairs well with vitamin C, though on its own the evidence for visible change is limited.

Source: NIH, National Library of Medicine