Cetaphil Healthy Renew Purified Peptides Night Cream

What the experts use it for.

The concerns the experts tie this product to, in their own words. Paid and founder takes don't count.

Redness2 experts

“This is again formulated especially for redness reactive skin that helps to reduce the appearance of redness, calm and soothe your skin but also help to support your skin barrier.”

Dr. Jenny Liu, watch at 15:10

Irritated or reactive skin2 experts

“At times when our skin gets really irritated, certain products can cause additional burning sensation, and I've had that experience with different types of moisturizers, but never with this one.”

Dr. Jenny Liu, watch at 10:14

Skin barrier support2 experts

“It will help strengthen and soothe the skin barrier with nourishing ingredients.”

Dr. Aleksandra Brown, watch at 22:23

Eczema1 expert

“I love this one because it is the most effective at really repairing dry skin, flaky skin, or eczema prone skin.”

The Budget Dermatologist, watch at 12:48

Flaky dry patches1 expert

“I love this one because it is the most effective at really repairing dry skin, flaky skin, or eczema prone skin.”

The Budget Dermatologist, watch at 12:48

Rough or uneven texture1 expert

“This wrinkle cream is designed to nourish the skin overnight reducing the fine lines and improving skin tone and texture.”

Dr. Aleksandra Brown, watch at 22:23

Fine lines and wrinkles1 expert

“This wrinkle cream is designed to nourish the skin overnight reducing the fine lines and improving skin tone and texture.”

Dr. Aleksandra Brown, watch at 22:23

Loss of firmness1 expert

“This is a super nourishing night cream designed specifically for mature skin to support firmness, hydration, barrier repair while you sleep.”

Dr. Aleksandra Brown, watch at 13:49

Calming retinoid irritation1 expert

“Especially if you're using retinoids and need extra support.”

Dr. Aleksandra Brown, watch at 13:49

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored

Dr. Aleksandra Brown

152k subs

✓Yay

"This is a super nourishing night cream designed specifically for mature skin to support firmness, hydration, barrier repair while you sleep. I love this for skin that feels dry, tight, or less resilient overnight. Especially if you're using retinoids and need extra support. The texture is pretty rich but not heavy. It absorbs really well. Helps skin feel more comfortable and hydrated by the morning. I love it as the final step in an evening routine. It can be used face, neck, and chest."

All 2 takes from Dr. Aleksandra Brown

The Best Drugstore Skincare for Mature Skin, According to a Derm

"This is a super nourishing night cream designed specifically for mature skin to support firmness, hydration, barrier repair while you sleep. I love this for skin that feels dry, tight, or less resilient overnight. Especially if you're using retinoids and need extra support. The texture is pretty rich but not heavy. It absorbs really well. Helps skin feel more comfortable and hydrated by the morning. I love it as the final step in an evening routine. It can be used face, neck, and chest."

Dermatologist's Winter Skincare Routine: AM & PM Steps for Healthy Skin | Dr. Aleksandra Brown

"I love the way this feels on my skin. This wrinkle cream is designed to nourish the skin overnight reducing the fine lines and improving skin tone and texture. It's really perfect for that sensitive skin, provides hydration, it will target the signs of aging, it will tackle the dullness and uneven skin tone for radiant glow by the morning. It will help strengthen and soothe the skin barrier with nourishing ingredients."

Dr. Daniel Sugai

723k subs

✓Yay

"With the moisturizers being so important in your 40s because we start to get drier skin, it's important to get your moisturizer game up, getting really good nourishing moisturizers and consider those with peptides now because peptides are cell signalers and they will tell your skin to make more skin, thicker skin. [...] Cetaphil and Neutrogena are affordable options with peptides in their moisturizers."

Dr. Jenny Liu

324k subs

✓Yay

"We chose it for about $10.99 at Target. This is actually one of my personal favorite drugstore moisturizers. Even though I don't have sensitive skin, it does get sensitized eyes and sensitive that time of the month, and this is one that I've actually been able to use consistently when my skin has not been the healthiest. It does not burn on my skin. I actually love the formulation. I love the texture. And the fact that it doesn't burn on my skin when my skin is sensitive."

All 3 takes from Dr. Jenny Liu

Sensitive Skin routine for less then $100 from a dermatologist | Dr. Jenny Liu

"We chose it for about $10.99 at Target. This is actually one of my personal favorite drugstore moisturizers. Even though I don't have sensitive skin, it does get sensitized eyes and sensitive that time of the month, and this is one that I've actually been able to use consistently when my skin has not been the healthiest. It does not burn on my skin. I actually love the formulation. I love the texture. And the fact that it doesn't burn on my skin when my skin is sensitive."

Dermatologist Ranks Favorite Cetaphil Products | Dr. Jenny Liu

"At times when our skin gets really irritated, certain products can cause additional burning sensation, and I've had that experience with different types of moisturizers, but never with this one. I love it for that reason that it's nourishing but not heavy or occlusive, but very calming and soothing."

Skincare routine for sensitive and rosacea-prone skin by Dermatology | Dr. Jenny Liu

"So the first one is the Cetaphil redness relieving night moisturizer. This is again formulated especially for redness reactive skin that helps to reduce the appearance of redness, calm and soothe your skin but also help to support your skin barrier."

Dr Dray

2.69M subs

✓Yay

"I finished the Cetaphil Healthy Renew night cream love that I have a backup it's like a really nice rich facial moisturizer"

All 8 takes from Dr Dray

My Thoughts On ISDIN Retinal Advanced Serum

"The night cream it's really rich."

Skincare, Makeup, & Chatting 💁🏻‍♀️💄

"I just hopped out of the shower and I'm coming in with the Cetaphil Healthy Renew night cream. The drugstore is really bringing ingredient packages that once were only available in the air quotes medical grade skin care, which is just a marketing term, the more expensive brands."

New Skincare & Trying On Halara Activewear

"This is so lux. I saw a comment though from one of you all that the smell kind of bothers you. It does kind of have a little bit of a cheesy aroma to it. It's fragrance free, so I get what you're saying there, but it doesn't linger, so I guess it doesn't bother me, but I can get why you might find that odd. It's super rich. It's really good as a night cream, especially in the colder winter months. And I really like it on my neck."

SEPTEMBER 2023 SKINCARE FAVORITES

"This particular night cream is so rich. It's great if you've got dry and or sensitive skin because it really helps with moisture retention, plumping, smoothing, and reducing the symptoms of sensitivity like burning, stinging, redness, irritation. If you live somewhere where you get cold winter winds and dry indoor air with the heaters and whatnot and you need and love a very rich, thick, heavy duty night cream, definitely check this out."

Using A Clay Mask For Oily Skin

"I have the Cetaphil Healthy Renew night cream. This is moving into the colder months if you want something real thick, tap into this. I've been super impressed by it. I mean, that consistency is lovely."

DRUGSTORE SKINCARE FOR MATURE SKIN 2023 | Dermatologist

"It has shea butter and it also has Arginine so that's anti-inflammatory. It has panto lactone which is another name for panthenol, panthenol is a really good moisturizing ingredient and can help improve skin elasticity. The Skin Renewing Night Cream is one of their most underrated products in their portfolio. This is so good. As I said, peptides are becoming more accessible. It's not cheap at 25, but it's a really good one."

Skincare In Your Nose | Skincare Vlog

"I finished the Cetaphil Healthy Renew night cream love that I have a backup it's like a really nice rich facial moisturizer"

How to prevent HAIR WAXING FAILS | bumps, breakouts, redness, ingrown hairs, burns| Dr Dray

"Another great option is Cetaphil's redness relieving night moisturizer, and they also make one for the daytime that has a little bit of sunscreen in it. That product also has niacinamide and licorice root."

The Budget Dermatologist

724k subs

✓Yay

"The Cetaphil Skin Renewing Night Cream is one of my all-time favorite night creams. [...] I love this one because it is the most effective at really repairing dry skin, flaky skin, or eczema prone skin. It is more of a balm like texture, so it's kind of even thicker than a cream but it's not an ointment. It's [...] very occlusive on the skin but not greasy or anything like that compared to Vaseline or something. This is an incredible product."

Top Pick: night cream for eczema

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Niacinamide

Niacinamide has evidence behind it for redness, uneven tone and supporting the skin barrier, and it is usually well tolerated even by skin that reacts to most things.

Source: DermNet

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

Vitamin E

Vitamin E is an antioxidant, and it is often in a formula to keep the other ingredients stable rather than as the active itself. It pairs well with vitamin C, though on its own the evidence for visible change is limited.

Source: NIH, National Library of Medicine

Frequently asked.

What is Cetaphil Healthy Renew Purified Peptides Night Cream?

A rich, fragrance-free night cream from Cetaphil, designed to moisturize and support the skin barrier overnight, especially for dry or sensitive skin.

Is Cetaphil Healthy Renew Purified Peptides Night Cream worth it?

Yes. All 5 gurus who reviewed it give it their stamp of approval, for a Guru Score of 90%.

What is Cetaphil Healthy Renew Purified Peptides Night Cream's Guru Score?

Cetaphil Healthy Renew Purified Peptides Night Cream holds a Guru Score of 90%. That is our read on how warmly the experts talk about it, based on the verdicts of 5 expert reviewers we have collected. At least one expert has named it a Top Pick in its category.

Who is Cetaphil Healthy Renew Purified Peptides Night Cream best for?

Cetaphil Healthy Renew Purified Peptides Night Cream is generally suited to dry skin and sensitive skin.

What is Cetaphil Healthy Renew Purified Peptides Night Cream good for, according to the experts?

In their reviews, experts say Cetaphil Healthy Renew Purified Peptides Night Cream is good for redness (2 experts), irritated or reactive skin (2 experts), skin barrier support (2 experts), eczema (1 expert), flaky dry patches (1 expert) and rough or uneven texture (1 expert).

Is Cetaphil Healthy Renew Purified Peptides Night Cream good for redness?

2 experts who reviewed Cetaphil Healthy Renew Purified Peptides Night Cream say it is. Dr. Jenny Liu put it this way: “This is again formulated especially for redness reactive skin that helps to reduce the appearance of redness, calm and soothe your skin but also help to support your skin barrier.”