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Centellian24 Expert Madeca Cream Active Renew PDRN.

Centellian24 Expert Madeca Cream Active Renew PDRN
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Moisturizers
About this product

A rich, soothing moisturizer cream formulated with PDRN (plant-derived DNA), centella asiatica extract, hyaluronic acid and cooling botanicals, designed for post-procedure recovery and sensitive skin.

Full ingredients

Water, Glycerin, Dipropylene Glycol, Caprylic/​Capric Triglyceride, Hydrogenated Poly (C6-14 Olefin), Glyceryl Stearate, Pentaerythrityl Tetraethylhexanoate, Niacinamide, Methyl Trimethicone, Vinyl Dimethicone, Cetearyl Alcohol, Rosa Damascena Flower Water, Polyglyceryl-10 Laurate, Sodium Dna (2,000 Ppm), Madecassic Acid (1,600 Ppm), Asiaticoside, Asiatic Acid, Centella Asiatica Extract, Glutathione, Caffeine, Beta-Sitosterol, Phytosterols, Laminaria Japonica Extract, Aloe Barbadensis Leaf Extract, Dioscorea Japonica Root Extract, Ulmus Davidiana Root Extract, Viola Mandshurica Flower Extract, Sodium Hyaluronate, Dimethylsilanol Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hyaluronic Acid, Potassium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Dimethylsilanol, Sodium Acetylated Hyaluronate, 1,2-Hexanediol, Panthenol, C10-18 Triglycerides

More from Centellian24 4 products · Guru Score 86% →

Guru Score

Not verified

Score withheld

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No independent takes

All 3 takes here are sponsored by the brand. With no independent take to weigh, there is not enough to publish a verified score. The takes are below, each labeled.

What they liked

  • Absorbs quickly without heaviness
  • Calms redness visibly
  • Silky, velvet matte finish

What they flagged

  • Contains essential oils, may irritate sensitive skin

What the gurus are saying

This cream earns consistent praise for its ability to visibly calm redness and soothe irritated skin, with the cooling complex genuinely lowering skin temperature by about six degrees to reduce inflammation. Gurus highlight the elegant balance of the formula (cushiony and hydrating without feeling heavy or greasy) and its rapid absorption, making it especially effective for recovery after intense treatments like microneedling; one expert used it nightly after over-exfoliation and saw rough, stinging skin fully resolved by day five. The light lavender scent from essential oils is worth noting if you're sensitive to those.
Synthesized from 3 expert reviews · most recent take July 2026

Type

MoisturizersCream

Formula notes

Fragrance-freeNo drying alcohol

Where to buy

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What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

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Gothamista
Gothamista
683k subs
✓Yay
"I personally like this more than the other Centellian24 moisturizers, which are also really really good, but this one just stands out a bit more for me. In Korea, Centellian24 is a pharmaceutical grade brand, you see these moisturizers in every single pharmacy. I really love that this cream also has the ability to bring your skin's temperature down by 6 degrees, using an ingredient called beta sterile (I probably mispronounced it) for the cooling effect."
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All 2 takes from Gothamista
Summer Korean Skincare Essentials! Mid-Year Top Picks 2026
"It's very moisturizing and it leaves kind of like a velvet matte finish. It's soothing and calming and it does so visibly. It really calms down any kind of redness. They have a cooler complex which can reduce the skin's temperature by six degrees. They use beta-sterile, [...] a plant ingredient that can instantly cool down the temperature of the skin. [...] This has their 5D PDRN matrix, which includes the salmon DNA. It's in a complex with four other plant-derived PDRNs."
My Heatwave Survival Must-Haves!
"I personally like this more than the other Centellian24 moisturizers, which are also really really good, but this one just stands out a bit more for me. In Korea, Centellian24 is a pharmaceutical grade brand, you see these moisturizers in every single pharmacy. I really love that this cream also has the ability to bring your skin's temperature down by 6 degrees, using an ingredient called beta sterile (I probably mispronounced it) for the cooling effect."
James Welsh
James Welsh
1.58M subs
✓Yay
"I've been enjoying this cream on and off. [...] For me, the real strength of this formula is the combination of ingredients rather than any one ingredient alone. [...] It's cushiony with an elastic feel that wraps the skin without feeling greasy or suffocating."
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Lab Muffin Beauty Science
Lab Muffin Beauty Science
863k subs
✓Yay
"Centellian24 is a really well-known Korean pharmaceutical brand known for solid, reliable, properly formulated and tested products. This contains their standard TECA, which is soothing, plus panthenol, a classic soothing ingredient, and PDRN, five types of it including salmon, rose, centella, heartleaf and marine. It's a recovery product but also has firming effects shown in their clinical testing."
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What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Niacinamide

Niacinamide has evidence behind it for redness, uneven tone and supporting the skin barrier, and it is usually well tolerated even by skin that reacts to most things.

Source: DermNet

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

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