Anua

PDRN Hyaluronic Acid 100 Moisturizing Cream.

Serums

About this product

A lightweight gel-cream moisturizer combining PDRN (salmon DNA extract) and a hyaluronic acid complex, designed to hydrate and soften skin without heaviness.

Full ingredients

Water, Squalane, Glycerin, Niacinamide, Pentylene Glycol, 1,2-Hexanediol, Sodium Dna, Hydrolyzed Collagen, Sodium Hyaluronate, Melia Azadirachta Leaf Extract, Hydrolyzed Hyaluronic Acid, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Hyaluronic Acid, Aloe Barbadensis Flower Extract, Solanum Melongena (Eggplant) Fruit Extract, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Curcuma Longa (Turmeric) Root Extract, Centella Asiatica Leaf Extract, Diphenylsiloxy Phenyl Trimethicone, Pca Dimethicone, Butylene Glycol, Propanediol, Ammonium Acryloyldimethyltaurate/VP Copolymer, Diglycerin, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C12-20 Alkyl Glucoside, Methylpropanediol, Ethylhexylglycerin, Adenosine, Sodium Phytate, Aminomethyl Propanediol, Pvm/Ma Copolymer, Madecassoside, C12-13 Alketh-9, Dimethylsilanol Hyaluronate, Hydrolyzed Sodium Hyaluronate, Asiaticoside, Potassium Hyaluronate

Guru Score

68%

Mixed

Early verdict · Few reviews so far

3Gurus

1Yay

2Mixed

0Nay

What the gurus are saying

This cream earns consistent praise for being weightless and fast-absorbing, leaving skin hydrated without any greasy feel, which makes it especially well-suited as a daytime moisturizer. The formula contains far more hyaluronic acid than PDRN, so think of it as a light hydrating gel rather than a PDRN treatment; those with oily or combination skin may find it works best layered with other products or as part of a routine, whereas it alone may not be enough hydration for drier skin types.

Synthesized from 3 expert reviews · most recent take June 2026

Best for

Dry skin Sensitive skin

Type

SerumsCream

Key actives

Niacinamide Hyaluronic acid Squalane

Formula notes

Fragrance-freeNo drying alcohol

Where to buy

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What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored

CYoung

94k subs

~Mixed

"I recommend this one more for oily combo skin because it's a very light gel type. It comes in a bigger size so it lasts longer, and it works pretty well before makeup too. But in terms of the PDRN ingredient, they put really little in it, there's actually more hyaluronic acid, so you can think of it as just a light hydrating, gel like cream. For my skin, using this alone isn't enough, so I'll give it a B."

Nipun Kapur

408k subs

~Mixed

"The Anua cream is something I have used. It's a great moisturization. It's a great cream from a moisturization perspective. I believe the way it is formulated, it can be used by all skin types, normal, dry, combination, literally everyone can use it. But again, it is just going to moisturize your skin. And the story ends there."

Gothamista

684k subs

~Yay

"I'm going to start with this one from Anua. Their PDRN Hyaluronic Acid 100 Moisturizing Cream. Honestly, I like this mostly because of just how good it makes my skin look. [...] It is so so lightweight. Actually, it's weightless. It's a light creamy gel that absorbs so fast, but at the same time, it feels hydrating on the skin. It leaves a greaseless glow and you can't really even feel anything other than your skin just feels really soft and hydrated. It's like it just sinks in there and does its work. This is almost your perfect daytime moisturizer. [...] Anua uses this salmon DNA PDRN. They've also formulated a 10 type hyaluronic acid complex which is supposed to have the ability to trap moisture within the deeper layers of the epidermis all the way up to the top."

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Niacinamide

Niacinamide has evidence behind it for redness, uneven tone and supporting the skin barrier, and it is usually well tolerated even by skin that reacts to most things.

Source: DermNet

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

Frequently asked.

What is Anua PDRN Hyaluronic Acid 100 Moisturizing Cream?

A lightweight gel-cream moisturizer combining PDRN (salmon DNA extract) and a hyaluronic acid complex, designed to hydrate and soften skin without heaviness.

Is Anua PDRN Hyaluronic Acid 100 Moisturizing Cream worth it?

The gurus mostly approve it, but with enough reservations to keep it in the middle at a Guru Score of 68%.

What is Anua PDRN Hyaluronic Acid 100 Moisturizing Cream's Guru Score?

Anua PDRN Hyaluronic Acid 100 Moisturizing Cream holds a Guru Score of 68%. That is our read on how warmly the experts talk about it, based on the verdicts of 3 expert reviewers we have collected.