Altreno Tretinoin Lotion 0.05%: a Guru Score of 76%

What the experts use it for.

The concerns the experts tie this product to, in their own words. Paid and founder takes don't count.

Calming retinoid irritation3 experts

“Altreno lotion is a newer form of tretinoin, tretinoin in a lotion, and it's a lot less drying and irritating.”

Irritated or reactive skin1 expert

“It does help with some of the irritation, but you can still experience peeling whenever you use your tretinoin regardless of whether you're using like a retinol over the counter or the actual tretinoin.”

Dr. Aleksandra Brown, watch at 14:02

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored

Doctorly

3.59M subs

✓Yay

"I cycle back to Altreno, which is a prescription tretinoin."

Dr Dray

2.69M subs

✓Yay

"Your dermatologist might try to prescribe other topical retinoids in vehicles that help reduce irritation, such as Altreno lotion, which contains hyaluronic acid and collagen. It is often better tolerated, it's a lot more moisturizing, and it's formulated to really address the dryness and sensitivity issues, but there's no guarantee with that."

All 5 takes from Dr Dray

Tretinoin Causes Death & Is Banned?

"We now have a newer form of tretinoin called Altreno lotion, it is in a much more like moisturizing hydrating base, it has hyaluronic acid, it has collagen. People seem to do better with that, but I also have had patients say this is very irritating, I don't like it. So I don't know if a lot of that is just the drug companies hyping up the base. In Altreno lotion it's also significantly more expensive."

5 Skincare Myths That Are Ruining Your Skin

"Altreno lotion, a topical retinoid is formulated with hyaluronic acid and collagen to be more hydrating, more moisturizing, and it is allegedly a lot less drying and irritating."

Can You Mix Azelaic Acid With Anything? Dermatologist Q&A

"Your dermatologist might try to prescribe other topical retinoids in vehicles that help reduce irritation, such as Altreno lotion, which contains hyaluronic acid and collagen. It is often better tolerated, it's a lot more moisturizing, and it's formulated to really address the dryness and sensitivity issues, but there's no guarantee with that."

Tretinoin SKIN THINNING & FAT LOSS | *Response Video* 🤔

"Altreno lotion is a newer form of tretinoin, tretinoin in a lotion, and it's a lot less drying and irritating. It's formulated with hyaluronic acid, so it's safe to use."

Hydrocortisone on Your Face? A Dermatologist Explains the Risks

"Altreno is tretinoin 0.05% in a lotion vehicle instead of a cream. The vehicle contains hyaluronic acid and collagen, which are moisturizing. It's a really nice vehicle. It tends to be expensive though, so heads up if you're paying for this out of pocket."

Dr. Aleksandra Brown

153k subs

✓Yay

"Altreno lotion, this is the 0.05%. It's a little bit newer hydrating formula. Really well tolerated. I do have this prescription. I like it. It spreads really nice."

All 3 takes from Dr. Aleksandra Brown

How a Dermatologist Transitions Her Skincare for Spring & Summer | Dr. Aleksandra Brown

"This is a brand name. I'll tell you, my insurance did not cover this. I paid probably over 100 bucks for this, too. But it lasts a very long time. So, if you're somebody who wants that gel texture, but you don't want to be too irritated with the generic tretinoin, which is tretinoin lotion. It feels like gel. I know it says lotion, but it feels just like gel. Is very nice option, a very good alternative. I apply this directly on top of my serum at bedtime, and then I do moisturizer on top."

Dermatologist's Winter Skincare Routine: AM & PM Steps for Healthy Skin | Dr. Aleksandra Brown

"It does help with some of the irritation, but you can still experience peeling whenever you use your tretinoin regardless of whether you're using like a retinol over the counter or the actual tretinoin. You only want to use like a pea-size amount and cover your entire face. So I like having the toner underneath because it really spreads the cream nice. Sometimes the cream is a little bit harder to spread, and having that hydration underneath helps the spread much, much easier."

Retinol, Retinal, Tretinoin: What’s the Difference?

"Altreno lotion, this is the 0.05%. It's a little bit newer hydrating formula. Really well tolerated. I do have this prescription. I like it. It spreads really nice."

No BS Beauty

89k subs

✓Yay

"I love the Altreno lotion. This is prescription. So, I can't link to it below, but um I just had my regular doctor write out a prescription for it and I had it filled at the pharmacy and just paid um I think I went to Costco for this one. Walgreens was really expensive, but Costco is actually ridiculously cheap. And this one's nice. So, if you have dry skin, this is a nice prescription retinoid that doesn't dry your skin out like a lot of them otherwise the prescription ones can."

All 2 takes from No BS Beauty

Top 50 Best Skincare Products of 2023 💖✔ Part Two - My Favorite Skincare Products of the Year!

"The Altreno Tretinoin Lotion 0.05% is a really hydrating version of tretinoin. I had tried tretinoin three or four years ago and it dried my skin out, and I was convinced I was never going to use it again until this one came out. My skin tolerates this wonderfully. It applies nicely, and it doesn't give me any redness, irritation, or flakiness. It's a winner."

The One Anti-Aging Step That I Won't Ever Skip? 5 Skincare Steps to Never Miss for Anti-Aging

"I love the Altreno lotion. This is prescription. So, I can't link to it below, but um I just had my regular doctor write out a prescription for it and I had it filled at the pharmacy and just paid um I think I went to Costco for this one. Walgreens was really expensive, but Costco is actually ridiculously cheap. And this one's nice. So, if you have dry skin, this is a nice prescription retinoid that doesn't dry your skin out like a lot of them otherwise the prescription ones can."

Lab Muffin Beauty Science

865k subs

✓Yay

"There are some fancier versions like Altreno which has that nicer lotion base it's less irritating"

Darnell Cox | 50+ Healthy Aging Expert

55k subs

✓Yay

"It's called Altreno, A-L-T-R-E-N-O. It is a prescription strength tretinoin that is formulated with other types of ingredients that helps ease the irritation."

Dr Alexis Stephens

582k subs

✓Yay

"It's got glycerin in here, they also have hyaluronic acid as well as a soluble collagen. It just really kicks everything up a notch. I'm using just one pea-sized amount and that pea-sized amount is going to be distributed evenly all over my face. I [...] have now graduated to a prescription strength, but trust me it took me years to get to this point. [...] You absolutely have to wear sun protection in the morning anytime you're using retinol at night time."

Gothamista

683k subs

✓Nay

"The most recent retinoids I've been using are prescription. [...] I was using Altreno, which has the most elegant hydrating jelly texture. I had to stop using that because I felt the formula, unfortunately as beautiful as it was, it's just a little too strong for my skin even after six months."

DermAngelo

968k subs

✓Yay

"[Altreno] Tretinoin Lotion is one of my favorites. One thing that makes this one super gentle is likely the vehicle that it comes in. It's almost gel-like, not truly a lotion. No night routine for me is complete without a retinoid."

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

Frequently asked.

What is Altreno Tretinoin Lotion 0.05%?

Altreno is a prescription tretinoin 0.05% lotion in a hydrating base containing hyaluronic acid and collagen, designed to deliver a topical retinoid with less dryness and irritation.

Is Altreno Tretinoin Lotion 0.05% worth it?

Mostly yes. 8 of the 9 gurus who reviewed it give it their stamp of approval, for a Guru Score of 76%.

What is Altreno Tretinoin Lotion 0.05%'s Guru Score?

Altreno Tretinoin Lotion 0.05% holds a Guru Score of 76%. That is our read on how warmly the experts talk about it, based on the verdicts of 9 expert reviewers we have collected.

Who is Altreno Tretinoin Lotion 0.05% best for?

Altreno Tretinoin Lotion 0.05% is generally suited to dry skin and sensitive skin.

What is Altreno Tretinoin Lotion 0.05% good for, according to the experts?

In their reviews, experts say Altreno Tretinoin Lotion 0.05% is good for calming retinoid irritation (3 experts) and irritated or reactive skin (1 expert).

Is Altreno Tretinoin Lotion 0.05% good for calming retinoid irritation?

3 experts who reviewed Altreno Tretinoin Lotion 0.05% say it is. Dr Dray put it this way: “Altreno lotion is a newer form of tretinoin, tretinoin in a lotion, and it's a lot less drying and irritating.”